公开(公告)号：US20080294032A1

公开(公告)日：2008-11-27

申请号：US10573242

申请日：2004-09-23

申请人： Richard Levenson ,  Paul J. Cronin ,  Kirk William Gossage ,  Clifford C. Hoyt

发明人： Richard Levenson ,  Paul J. Cronin ,  Kirk William Gossage ,  Clifford C. Hoyt

IPC分类号： A61B6/00

CPC分类号： G01N33/5091 ,  A61B5/0059 ,  A61B2562/0242 ,  B82Y5/00 ,  B82Y10/00 ,  G01J3/32 ,  G01J3/4406 ,  G01J3/453 ,  G01N21/6428 ,  G01N21/6456

摘要： The invention features a method including: (i) providing spectrally resolved information about light coming from different spatial locations in a sample comprising deep tissue in response to an illumination of the sample, wherein the light includes contributions from different components in the sample; (ii) decomposing the spectrally resolved information for each of at least some of the different spatial locations into contributions from spectral estimates associated with at least some of the components in the sample; and (iii) constructing a deep tissue image of the sample based on the decomposition to preferentially show a selected one of the components.

摘要翻译： 本发明的特征在于一种方法，包括：（i）响应于样品的照明，提供关于来自包含深层组织的样品中的不同空间位置的光的光谱解析信息，其中所述光包括来自样品中不同组分的贡献; （ii）将所述不同空间位置中的至少一些中的每一个的所述光谱解析信息分解为与所述样本中的至少一些组件相关联的频谱估计的贡献; 和（iii）基于分解构建样品的深层组织图像，以优先显示所选择的组分之一。

公开(公告)号：US20090257640A1

公开(公告)日：2009-10-15

申请号：US12401430

申请日：2009-03-10

申请人： Kirk William Gossage ,  Tyna A. Hope

发明人： Kirk William Gossage ,  Tyna A. Hope

IPC分类号： G06K9/00

CPC分类号： G06K9/0014 ,  G06K9/4642 ,  G06T7/11 ,  G06T2207/10056 ,  G06T2207/30024

摘要： Methods disclosed herein include: (a) determining positions of a plurality of cells based on one or more images of the cells; (b) for at least some of the plurality of cells, generating a matrix that includes two-dimensional information about positions of neighboring cells, and determining one or more numerical features based on the information in the matrix; and (c) classifying the at least some of the plurality of cells as belonging to at least one of multiple classes based on the numerical features.

摘要翻译： 本文公开的方法包括：（a）基于小区的一个或多个图像来确定多个小区的位置; （b）对于所述多个小区中的至少一些小区，生成包括关于相邻小区的位置的二维信息的矩阵，以及基于所述矩阵中的信息来确定一个或多个数字特征; 以及（c）基于所述数值特征将所述多个小区中的至少一些小区归类为属于多个类别中的至少一个。

公开(公告)号：US08103081B2

公开(公告)日：2012-01-24

申请号：US12401430

申请日：2009-03-10

申请人： Kirk William Gossage ,  Tyna A. Hope

发明人： Kirk William Gossage ,  Tyna A. Hope

IPC分类号： G06K9/00

CPC分类号： G06K9/0014 ,  G06K9/4642 ,  G06T7/11 ,  G06T2207/10056 ,  G06T2207/30024

摘要： Methods disclosed herein include: (a) determining positions of a plurality of cells based on one or more images of the cells; (b) for at least some of the plurality of cells, generating a matrix that includes two-dimensional information about positions of neighboring cells, and determining one or more numerical features based on the information in the matrix; and (c) classifying the at least some of the plurality of cells as belonging to at least one of multiple classes based on the numerical features.

摘要翻译： 本文公开的方法包括：（a）基于小区的一个或多个图像来确定多个小区的位置; （b）对于所述多个小区中的至少一些小区，生成包括关于相邻小区的位置的二维信息的矩阵，以及基于所述矩阵中的信息来确定一个或多个数字特征; 以及（c）基于所述数值特征将所述多个小区中的至少一些小区归类为属于多个类别中的至少一个。