公开(公告)号：US11187709B2

公开(公告)日：2021-11-30

申请号：US16671242

申请日：2019-11-01

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Sascha Antoni ,  Christian Vogl

IPC: G01N33/82 ,  C07C401/00

Abstract: A reagent composition for releasing vitamin D compounds bound to vitamin D-binding protein and an in vitro method for the detection of a vitamin D compound in which the vitamin D compound is released from vitamin D-binding protein by the use of this reagent composition as well as the reagent mixture obtained in this manner. Also disclosed is the use of the reagent compositions to release vitamin D compounds as well as a kit for detecting a vitamin D compound.

公开(公告)号：US20200072854A1

公开(公告)日：2020-03-05

申请号：US16671242

申请日：2019-11-01

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Sascha Antoni ,  Christian Vogl

IPC: G01N33/82 ,  C07C401/00

Abstract: A reagent composition for releasing vitamin D compounds bound to vitamin D-binding protein and an in vitro method for the detection of a vitamin D compound in which the vitamin D compound is released from vitamin D-binding protein by the use of this reagent composition as well as the reagent mixture obtained in this manner. Also disclosed is the use of the reagent compositions to release vitamin D compounds as well as a kit for detecting a vitamin D compound.

公开(公告)号：US20170363649A1

公开(公告)日：2017-12-21

申请号：US15693903

申请日：2017-09-01

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Sascha Antoni ,  Christian Vogl

IPC: G01N33/82 ,  C07C401/00

CPC classification number: G01N33/82 ,  C07C401/00 ,  Y10T436/203332

Abstract: A reagent composition for releasing vitamin D compounds bound to vitamin D-binding protein and an in vitro method for the detection of a vitamin D compound in which the vitamin D compound is released from vitamin D-binding protein by the use of this reagent composition as well as the reagent mixture obtained in this manner. Also disclosed is the use of the reagent compositions to release vitamin D compounds as well as a kit for detecting a vitamin D compound.

公开(公告)号：US20150226753A1

公开(公告)日：2015-08-13

申请号：US14693985

申请日：2015-04-23

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Sascha Antoni ,  Christian Vogl

IPC: G01N33/82

CPC classification number: G01N33/82 ,  G01N2440/00 ,  Y10T436/203332

Abstract: A reagent composition for releasing vitamin D compounds bound to vitamin D-binding protein, an in vitro method for the detection of a vitamin D compound in which the vitamin D compound is released from vitamin D-binding protein by the use of this reagent composition and the reagent mixture obtained in this manner. The use of the disclosed reagent composition to release vitamin D compounds as well as a kit for detecting a vitamin D compound which contains the reagent composition for releasing vitamin D compounds in addition to common detecting reagents.

Abstract translation: 一种用于释放与维生素D结合蛋白结合的维生素D化合物的试剂组合物，用于检测其中维生素D化合物通过使用该试剂组合物从维生素D结合蛋白中释放的维生素D化合物的体外方法，以及 以这种方式获得的试剂混合物。 使用所公开的试剂组合物来释放维生素D化合物以及用于检测维生素D化合物的试剂盒，所述试剂盒除了常见的检测试剂之外还含有用于释放维生素D化合物的试剂组合物。