公开(公告)号：US09643882B2

公开(公告)日：2017-05-09

申请号：US14263653

申请日：2014-04-28

Applicant: SCHOTT AG

Inventor： Stephan Tratzky ,  Christof Kass ,  Rainer Eichholz ,  Peter Nass

IPC: C03C3/091 ,  C03C3/093 ,  C03C4/20 ,  C03C3/11 ,  C03C3/118 ,  A61J1/00 ,  A61J1/06

CPC classification number: C03C3/093 ,  A61J1/00 ,  A61J1/065 ,  C03C3/091 ,  C03C3/11 ,  C03C3/118 ,  C03C4/20

Abstract: Borosilicate glasses, preferably for use in the pharmaceutical sector, are provided. The borosilicate glasses are outstandingly suitable for the use as pharmaceutical primary packaging, such as phials or ampoules, since the aqueous or water-containing medicaments kept in the containers do not attack the glass significantly, and so the glass releases no, or only few, ions. The borosilicate glasses have the following composition in % by weight or consist thereof: SiO271-77; B2O39-12; Al2O35.5-8; Na2O6-8; K2O0.1-0.9; Li2O0-0.3; CaO0-1.5; BaO0-1; F0-0.3; Cl-0-0.3; and MgO + CaO + BaO + SrO 0-2.

公开(公告)号：US20170029319A1

公开(公告)日：2017-02-02

申请号：US15224433

申请日：2016-07-29

Applicant: SCHOTT AG

Inventor： Christof Kass ,  Stephan Tratzky ,  Reinhard Männl ,  Rainer Eichholz

IPC: C03C3/091 ,  A61K9/08 ,  A61J1/00 ,  C03C4/20

CPC classification number: C03C3/091 ,  A61J1/00 ,  A61K9/08 ,  C03C3/11 ,  C03C4/20 ,  C03C2204/00

Abstract: A zirconium-free neutral glass is provided that finds use in the pharmaceutical sector. The glass has a combination of alkali metal oxides of sodium, potassium and optionally lithium, and a controlled amount of aluminium oxide, which provides a zirconium-free and low-boron neutral glass having good hydrolytic stability, good acid and alkali stability and good devitrification properties. The glass includes the following components in % by weight: SiO2 72-82, B2O3  3-8, Al2O3  5-8, Na2O2.5-5.5, K2O3.6-8.4, Li2O  0-0.7, MgO  0-0.7, CaO  0-0.4, and TiO2  0-5, wherein Li2O + Na2O + K2O6.8-14.6, and K2O/Na2O ratio0.7-3.4.

公开(公告)号：US20160130170A1

公开(公告)日：2016-05-12

申请号：US15000072

申请日：2016-01-19

Applicant: SCHOTT AG

Inventor： Reinhard Maennl ,  Stephan Tratzky ,  Franz Jaeger

IPC: C03B23/09 ,  B65D1/09 ,  C03B21/06

CPC classification number: C03B23/092 ,  B65D1/09 ,  C03B21/06 ,  C03B23/049 ,  C03B23/11

Abstract: A method for producing glass vials, in particular pharmaceutical vials or pharmaceutical ampoules, from a glass tube is provided, the method including the following steps: (a) rotating the glass tube about a longitudinal axis thereof; (b) locally heating the glass tube from one side by means of at least one burner to at least the softening temperature of the glass; (c) reducing the diameter by pressing at least one forming body laterally against the heated region; and (d) separating the glass tube by means of a burner. A glass vial produced in such a way releases a reduced amount of alkali in accordance with ISO 4802 and has a decreased delamination tendency. Furthermore, in the hot-formed peripheral region, the alkali content is only slightly reduced when compared with the alkali content in the glass interior.

Abstract translation: 提供了一种从玻璃管制造玻璃小瓶，特别是药瓶或药用安瓿的方法，该方法包括以下步骤：（a）围绕其纵轴旋转玻璃管; （b）通过至少一个燃烧器将玻璃管从一侧局部加热至至少玻璃的软化温度; （c）通过将至少一个成形体横向压靠在加热区域上来减小直径; 和（d）借助燃烧器分离玻璃管。 以这种方式生产的玻璃小瓶根据ISO 4802释放减少量的碱，并且具有降低的分层趋势。 此外，在热成形周边区域中，与玻璃内部的碱含量相比，碱含量仅略微降低。