公开(公告)号：US20170218347A1

公开(公告)日：2017-08-03

申请号：US15515303

申请日：2015-10-07

Applicant: SYNGENTA PARTICIPATIONS AG

Inventor： Denis GRIBKOV

IPC: C12N9/10 ,  C12P19/44

CPC classification number: C12N9/1085 ,  C07C45/63 ,  C07C201/08 ,  C12P19/44 ,  C07C205/45 ,  C07C49/80

Abstract: The invention relates to a process for the preparation of a compound of formula I (I), wherein R1 is hydrogen, fluoro or chloro; which process comprises a) reacting a compound of formula II (II), wherein R1 is hydrogen, fluoro or chloro; with a nitration agent to the compound of formula (III), wherein R1 is hydrogen, fluoro or chloro; and b) reacting the compound of formula III with chlorine gas at temperature from 180° C. to 250° C. to the compound of formula I.