Artemisinins in the clinical and veterinary management of kinetoplastid infections
    11.
    发明申请
    Artemisinins in the clinical and veterinary management of kinetoplastid infections 失效
    青蒿素在动物原核生物感染的临床和兽医管理中的应用

    公开(公告)号:US20080152729A1

    公开(公告)日:2008-06-26

    申请号:US11644494

    申请日:2006-12-21

    CPC classification number: A61K31/366 A61K31/357 A61K36/282

    Abstract: The invention relates to the treatment of kintoplastid infections by administering a pharmaceutical composition containing an extract from the plant Artemisia annua. The invention also relates to isolated, semi-synthetic and synthetic artemisinins that show improved efficacy in treating kinetoplastid infections. This invention also relates to a method of treating kintoplastid infections with artelinic acid and artemisinins and where Artelinic acid is administered orally.

    Abstract translation: 本发明涉及通过施用含有来自艾蒿植物的提取物的药物组合物来治疗激素质感染。 本发明还涉及分离的,半合成的和合成的青蒿素,其在治疗动粒细胞感染中显示出改进的功效。 本发明还涉及一种用阿魏酸和青蒿素治疗激素质感染的方法,其中口服阿片ic酸。

    Step assembly for vehicles
    12.
    发明授权
    Step assembly for vehicles 失效
    车辆步进组装

    公开(公告)号:US5199731A

    公开(公告)日:1993-04-06

    申请号:US799435

    申请日:1991-11-26

    Inventor: Samuel K. Martin

    CPC classification number: B60R3/02

    Abstract: A step assembly (438) includes two step supporting members (444) which have proximal ends pivotally attached to the underside of a mounting bracket (440). The step supporting members (444) support a plurality of rungs (445). A step plate (446) is attached in cantilevered manner to each of the rungs (445) whereby a rear one of the step supporting members (444) is intermediate the step plate (446) and the front step supporting member. A transmission assembly is provided for causing distal ends of the step supporting members to contact the ground (G) and thereby acquire an extended, angularly inclined position. In one embodiment, the transmission assembly includes an actuator (470). In another embodiment, the transmission assembly includes a motor and cable assembly (472).

    Abstract translation: 台阶组件(438)包括两个台阶支撑构件(444),其具有枢转地附接到安装支架(440)的下侧的近端。 台阶支撑构件(444)支撑多个梯级(445)。 台阶板(446)以悬臂方式连接到每个梯级(445),由此台阶支撑构件(444)中的后一个在台阶板(446)和前台阶支撑构件之间。 提供了一种变速组件,用于使台阶支撑构件的远端接触地面(G),从而获得延伸的有角度倾斜的位置。 在一个实施例中,传动组件包括致动器(470)。 在另一个实施例中,变速器组件包括马达和缆索组件(472)。

    Antimalarial compositions and methods
    13.
    发明授权
    Antimalarial compositions and methods 失效
    抗疟药组合物和方法

    公开(公告)号:US4897403A

    公开(公告)日:1990-01-30

    申请号:US936677

    申请日:1986-11-18

    CPC classification number: A61K31/47 Y10S514/895

    Abstract: An antimalarial composition contains as the active ingredient a mixture of chemical compound effective in reversing the resistance of cancer cells to chemotherapy drugs and at least one antimalarial agent. A method for treating malaria in mammals comprises administering a composition containing the active ingredient. A method for reducing the resistance of a malarial parasite to an antimalarial agent comprises administering a composition containing the active ingredient.

    Abstract translation: 抗疟药组合物含有有效地逆转癌细胞对化疗药物和至少一种抗疟剂的抗性的化合物的混合物作为活性成分。 用于治疗哺乳动物疟疾的方法包括施用含有活性成分的组合物。 一种降低疟疾寄生虫对抗疟药的抗性的方法包括给予含有活性成分的组合物。

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