Abstract:
The invention relates to the treatment of kintoplastid infections by administering a pharmaceutical composition containing an extract from the plant Artemisia annua. The invention also relates to isolated, semi-synthetic and synthetic artemisinins that show improved efficacy in treating kinetoplastid infections. This invention also relates to a method of treating kintoplastid infections with artelinic acid and artemisinins and where Artelinic acid is administered orally.
Abstract:
A step assembly (438) includes two step supporting members (444) which have proximal ends pivotally attached to the underside of a mounting bracket (440). The step supporting members (444) support a plurality of rungs (445). A step plate (446) is attached in cantilevered manner to each of the rungs (445) whereby a rear one of the step supporting members (444) is intermediate the step plate (446) and the front step supporting member. A transmission assembly is provided for causing distal ends of the step supporting members to contact the ground (G) and thereby acquire an extended, angularly inclined position. In one embodiment, the transmission assembly includes an actuator (470). In another embodiment, the transmission assembly includes a motor and cable assembly (472).
Abstract:
An antimalarial composition contains as the active ingredient a mixture of chemical compound effective in reversing the resistance of cancer cells to chemotherapy drugs and at least one antimalarial agent. A method for treating malaria in mammals comprises administering a composition containing the active ingredient. A method for reducing the resistance of a malarial parasite to an antimalarial agent comprises administering a composition containing the active ingredient.