公开(公告)号：US07087631B2

公开(公告)日：2006-08-08

申请号：US10620619

申请日：2003-07-17

申请人： Alex Nivorozhkin ,  John Van Duzer ,  Garry Southan ,  Siya Ram ,  Qi Zeng

发明人： Alex Nivorozhkin ,  John Van Duzer ,  Garry Southan ,  Siya Ram ,  Qi Zeng

IPC分类号： A61K31/41 ,  C07D257/04

CPC分类号： C07D257/04 ,  C07D401/10 ,  C07D401/12 ,  C07D403/12 ,  C07D405/04 ,  C07D405/12 ,  C07D409/12 ,  C07D417/12

摘要： The present invention relates to 5-Aryltetrazole Compounds, compositions comprising an effective amount of a 5-Aryltetrazole Compound, and methods for treating an inflammation disease, a reperfusion disease, or hyperuricemia in an animal in need thereof comprising administering to the animal an effective amount of a 5-Aryltetrazole compound.

摘要翻译： 本发明涉及5-芳基四唑化合物，包含有效量的5-芳基四唑化合物的组合物，以及用于治疗有需要的动物中炎性疾病，再灌注疾病或高尿酸血症的方法，其包括向所述动物施用有效量 的5-芳基四唑化合物。

公开(公告)号：US11098024B2

公开(公告)日：2021-08-24

申请号：US16741741

申请日：2020-01-13

申请人： Alex Nivorozhkin

发明人： Alex Nivorozhkin

IPC分类号： C07D311/80 ,  B01J8/02 ,  B01J8/00 ,  B01J31/10 ,  B01J21/08 ,  B01J27/12 ,  B01J29/08 ,  B01J29/85 ,  B01J35/02 ,  A61M11/04 ,  A24F40/40 ,  B01J29/40

摘要： The present invention is directed to methods of producing THC from CBD utilizing non-harsh methodology and resulting in substantially increased yields, as well as devices built upon these novel methods. The methods and devices are material efficient, and in certain embodiments, solvent-free. In particular, in certain embodiments, these methods and related devices are suitable for commercial production of THC from CBD. Furthermore, in certain embodiments, the present invention provides methods of producing THC from CBD in manner that affords tunability to select the ratio of THC-8 to THC-9.

公开(公告)号：US20050159418A1

公开(公告)日：2005-07-21

申请号：US11030416

申请日：2005-01-06

申请人： Alex Nivorozhkin ,  John Van Duzer ,  Garry Southan ,  Siya Ram ,  Qi Zeng

发明人： Alex Nivorozhkin ,  John Van Duzer ,  Garry Southan ,  Siya Ram ,  Qi Zeng

IPC分类号： A61K31/41 ,  A61K31/427 ,  A61K31/4439 ,  A61K31/496 ,  A61K31/5377 ,  A61P1/00 ,  A61P1/02 ,  A61P1/04 ,  A61P3/10 ,  A61P9/00 ,  A61P11/06 ,  A61P13/12 ,  A61P17/06 ,  A61P19/02 ,  A61P19/06 ,  A61P25/28 ,  A61P27/00 ,  A61P29/00 ,  A61P37/06 ,  A61P43/00 ,  C07D257/04 ,  C07D401/10 ,  C07D401/12 ,  C07D403/12 ,  C07D405/04 ,  C07D405/12 ,  C07D409/12 ,  C07D417/12 ,  A61K31/454 ,  C07D413/02 ,  C07D43/02

CPC分类号： C07D257/04 ,  C07D401/10 ,  C07D401/12 ,  C07D403/12 ,  C07D405/04 ,  C07D405/12 ,  C07D409/12 ,  C07D417/12

摘要： The present invention relates to 5-Aryltetrazole Compounds, compositions comprising an effective amount of a a 5-Aryltetrazole Compound, and methods for treating an inflammation disease, a reperfusion disease, or hyperuricemia in an animal in need thereof comprising administering to the animal an effective amount of a 5-Aryltetrazole compound.

摘要翻译： 本发明涉及5-芳基四唑化合物，包含有效量的5-芳基四唑化合物的组合物，以及用于治疗有需要的动物的炎症疾病，再灌注疾病或高尿酸血症的方法，其包括向所述动物施用有效量 的5-芳基四唑化合物。

公开(公告)号：US20210363125A1

公开(公告)日：2021-11-25

申请号：US17397457

申请日：2021-08-09

申请人： Alex Nivorozhkin

发明人： Alex Nivorozhkin

IPC分类号： C07D311/80 ,  B01J8/02 ,  B01J8/00 ,  B01J31/10 ,  B01J21/08 ,  B01J27/12 ,  B01J29/08 ,  B01J29/85 ,  B01J35/02 ,  A61M11/04 ,  A24F40/40 ,  B01J29/40

摘要： The present invention is directed to methods of producing THC from CBD utilizing non-harsh methodology and resulting in substantially increased yields, as well as devices built upon these novel methods. The methods and devices are material efficient, and in certain embodiments, solvent-free. In particular, in certain embodiments, these methods and related devices are suitable for commercial production of THC from CBD. Furthermore, in certain embodiments, the present invention provides methods of producing THC from CBD in manner that affords tunability to select the ratio of THC-8 to THC-9.

公开(公告)号：US20200223814A1

公开(公告)日：2020-07-16

申请号：US16741741

申请日：2020-01-13

申请人： Alex Nivorozhkin

发明人： Alex Nivorozhkin

IPC分类号： C07D311/80 ,  B01J8/02 ,  B01J8/00 ,  B01J31/10 ,  B01J21/08 ,  B01J27/12 ,  B01J29/40 ,  B01J29/08 ,  B01J29/85 ,  B01J35/02 ,  A61M11/04 ,  A24F40/40

摘要： The present invention is directed to methods of producing THC from CBD utilizing non-harsh methodology and resulting in substantially increased yields, as well as devices built upon these novel methods. The methods and devices are material efficient, and in certain embodiments, solvent-free. In particular, in certain embodiments, these methods and related devices are suitable for commercial production of THC from CBD. Furthermore, in certain embodiments, the present invention provides methods of producing THC from CBD in manner that affords tunability to select the ratio of THC-8 to THC-9.

公开(公告)号：US07078423B2

公开(公告)日：2006-07-18

申请号：US10197609

申请日：2002-07-18

申请人： Alex Nivorozhkin ,  John Van Duzer ,  Andrew Salzman ,  Garry Southan ,  Siya Ram ,  Qi Zeng ,  Csaba Szabo

发明人： Alex Nivorozhkin ,  John Van Duzer ,  Andrew Salzman ,  Garry Southan ,  Siya Ram ,  Qi Zeng ,  Csaba Szabo

IPC分类号： A61K31/41 ,  C07D257/04

CPC分类号： C07D257/04 ,  C07D401/10 ,  C07D401/12 ,  C07D403/12 ,  C07D405/04 ,  C07D405/12 ,  C07D409/12 ,  C07D417/12

摘要： The present invention relates to 5-Aryltetrazole compounds, compositions comprising a 5-Aryltetrazole compound, and methods for treating an inflammation disease, a reperfusion disease, hyperuricemia, gout, or tumor-lysis syndrome in an animal in need thereof comprising administering to the animal an effective amount of a 5-Aryltetrazole compound.

摘要翻译： 本发明涉及5-芳基四唑化合物，包含5-芳基四唑化合物的组合物，以及在有需要的动物中治疗炎症疾病，再灌注疾病，高尿酸血症，痛风或肿瘤溶解综合征的方法，其包括向所述动物施用 有效量的5-芳基四唑化合物。