公开(公告)号：US20170100345A1

公开(公告)日：2017-04-13

申请号：US15309190

申请日：2015-05-06

Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

Inventor： Antoni RIBAS ,  Helena ESCUIN-ORDINAS

IPC: A61K9/70 ,  A61K31/519 ,  A61K31/437 ,  A61K9/00 ,  A61K45/06

CPC classification number: A61K9/7023 ,  A61K9/0014 ,  A61K9/06 ,  A61K9/12 ,  A61K31/404 ,  A61K31/437 ,  A61K31/506 ,  A61K31/519 ,  A61K45/06 ,  A61K2300/00

Abstract: Methods for treating a wound are provided herein. Such methods include a step of contacting the wound with an effective amount of a BRAF inhibitor. In some aspects, BRAF inhibitors may be part of a pharmaceutical composition. In such case, the pharmaceutical composition may include an effective amount of a BRAF inhibitor and a pharmaceutically acceptable carrier. In certain aspects, the pharmaceutical composition is a topical agent comprising an ointment, cream liquid, gel, hydrogel, or a spray. Further, in some embodiments, a BRAF inhibitor or a pharmaceutical composition thereof may be part of wound dressing for use in treating a wound. In this case, the wound dressing may be impregnated or coated with the BRAF inhibitor or pharmaceutical composition thereof.