公开(公告)号：US20110029186A1

公开(公告)日：2011-02-03

申请号：US12935997

申请日：2009-04-02

申请人： Tomoyasu Ishikawa

发明人： Tomoyasu Ishikawa

IPC分类号： G06F7/00

CPC分类号： G07C5/0808

摘要： A failure diagnostic information generating apparatus includes a repair information acquiring unit that acquires repair information indicating the content of repair or replacement conducted for a vehicle malfunction or a cause of the malfunction; an malfunction-time vehicle information acquiring unit that acquires malfunction-time vehicle information indicating a vehicle state detected when the malfunction occurs; an instruction information generating unit that generates instruction information, usable for future repair or replacement, on the basis of the repair information and the malfunction-time vehicle information; and a recurrence information acquiring unit that acquires recurrence information indicating whether the malfunction has recurred after the repair or replacement. It is determined, using the recurrence information, whether the malfunction has recurred after the repair or replacement. On the basis of the determination result, the instruction information generating unit determines whether to generate instruction information or whether to use generated instruction information for future repair or replacement.

摘要翻译： 故障诊断信息生成装置包括维修信息取得部，其获取表示对于车辆故障进行的维修或更换的内容的修理信息或故障的原因; 故障时车辆信息获取单元，其获取指示在发生故障时检测到的车辆状态的故障时车辆信息; 指令信息生成单元，其基于修理信息和故障时间车辆信息生成可用于将来的维修或更换的指示信息; 以及重发信息获取单元，其获取指示在所述修复或更换之后所述故障是否复发的复发信息。 使用复发信息确定维修或更换后故障是否复发。 根据判定结果，指示信息生成部判断是否生成指示信息，或者是否使用生成的指示信息来进行将来的修理或替换。

公开(公告)号：US20100216788A1

公开(公告)日：2010-08-26

申请号：US12095543

申请日：2006-12-01

申请人： Tomoyasu Ishikawa ,  Kazuhiro Miwa ,  Masaki Seto ,  Hiroshi Banno ,  Youichi Kawakita

发明人： Tomoyasu Ishikawa ,  Kazuhiro Miwa ,  Masaki Seto ,  Hiroshi Banno ,  Youichi Kawakita

IPC分类号： A61K31/5377 ,  C07D487/04 ,  A61K31/519 ,  C07D413/14 ,  A61P35/00

CPC分类号： C07D487/04

摘要： The present invention provides a compound represented by the formula: wherein R1a is a hydrogen atom, R2a is a C1-6 alkyl group substituted by a group represented by —NR6a—CO—(CH2)n—SO2— optionally halogenated C1-4 alkyl wherein n is an integer of 1 to 4, R6a is a hydrogen atom or a C1-4 alkyl group, and —(CH2)n— is optionally substituted by C1-4 alkyl, R3a is a hydrogen atom or a C1-6 alkyl group, R4a is a halogen atom or a C1-6 alkyl group, R5a is a halogen atom or a C1-6 alkyl group, and Xa is a hydrogen atom or a halogen atom, or a salt thereof. The compound of the present invention has a superior tyrosine kinase inhibitory action, is highly safe, and is sufficiently satisfactory as a pharmaceutical product.

摘要翻译： 本发明提供由下式表示的化合物：其中R1a是氢原子，R2a是被-NR6a-CO-（CH2）n-SO2-代表的基团取代的C1-6烷基，任选被卤代的C 1-4烷基 其中n为1〜4的整数，R6a为氢原子或C1-4烷基， - （CH2）n-为C1-4烷基，R3a为氢原子或C1-6烷基 基团，R 4a是卤素原子或C 1-6烷基，R 5a是卤素原子或C 1-6烷基，X a是氢原子或卤素原子或其盐。 本发明的化合物具有优异的酪氨酸激酶抑制作用，是高度安全的，并且作为药物产品足够令人满意。

公开(公告)号：US20090066494A1

公开(公告)日：2009-03-12

申请号：US12208681

申请日：2008-09-11

申请人： Tomoyasu Ishikawa

发明人： Tomoyasu Ishikawa

IPC分类号： B60Q1/00

CPC分类号： G01S7/529 ,  G01S7/52004

摘要： A failure information detection device that detects abnormality of a vehicle-mounted device that is mounted in a vehicle has: an attachment detection portion that detects whether a first component part has been attached to the vehicle; an abnormality detection portion that detects abnormality of a second component part that is disposed on the first component part; and an abnormality information discernment portion that discerns that abnormality information regarding the abnormality is not based on a failure of the vehicle-mounted device if the attachment detection portion detects that the first component part has not been attached to the vehicle.

摘要翻译： 一种检测安装在车辆中的车载装置的异常的故障信息检测装置具有：检测第一部件是否已经安装在车辆上的附件检测部; 异常检测部，其检测配置在所述第一部件上的第二部件的异常; 以及异常信息识别部，其在所述附着检测部检测到所述第一部件未附接到所述车辆的情况下，识别出所述异常的异常信息不是基于所述车载装置的故障。

公开(公告)号：US07419973B2

公开(公告)日：2008-09-02

申请号：US11063715

申请日：2005-02-23

申请人： Tomoyasu Ishikawa ,  Shohei Hashiguchi ,  Yuji Iizawa

发明人： Tomoyasu Ishikawa ,  Shohei Hashiguchi ,  Yuji Iizawa

IPC分类号： A61K31/546 ,  A61P31/04 ,  C07F9/6561

CPC分类号： A61K31/675 ,  C07F9/65613

摘要： A cephem compound (particularly its crystal) represented by the formula [I], wherein X is CH3COOH, CH3CH2COOH or CH3CN, and n is 0 to 5, is useful as an antibacterial agent (particularly anti-MRSA agent) and shows superior quality such as high solid stability, possible long-term stable preservation and the like.

摘要翻译： 由式[I]表示的头孢烯化合物（特别是其结晶），其中X是CH 3 COOH，CH 3 CH 2 COOH或 CH 3 CN，n为0〜5，可用作抗菌剂（特别是抗MRSA剂），并且具有优异的质量，例如高固体稳定性，可能的长期稳定保存等 。

公开(公告)号：US06417175B1

公开(公告)日：2002-07-09

申请号：US09555949

申请日：2000-06-06

申请人： Tomoyasu Ishikawa ,  Shohei Hashiguchi ,  Yuji Iizawa

发明人： Tomoyasu Ishikawa ,  Shohei Hashiguchi ,  Yuji Iizawa

IPC分类号： C07D96561

CPC分类号： C07F9/65613 ,  C07D501/00

摘要： A novel cephem compound of the formula: wherein R1 is a phosphono group or a group convertible to a phosphono group; R2 is a hydrogen atom or a group having a linkage through a carbon atom; each of Q and X is a nitrogen atom or CH; Y is S, O or CH2; n is 0 or 1; one of R3 and R4 is a pyridinium group which may be substituted and the other is a hydrogen atom or hydrocarbon group which may be substituted, or R3 and R4 taken together may form a quaternalized nitrogen-containing heterocyclic ring which may be substituted, or its ester or its salt, which has a superior anti-bacterial activity, stability, absorbability, etc., a production thereof and a pharmaceutical composition containing it, is provided.

摘要翻译： 一种下式的新型头孢烯化合物：其中R1是膦酰基或可转换成膦酰基的基团; R2是氢原子或具有通过碳原子连接的基团; Q和X各自为氮原子或CH; Y是S，O或CH2; n为0或1; R3和R4之一是可以被取代的吡啶鎓基，另一个是可被取代的氢原子或烃基，或者R 3和R 4可以一起形成可被取代的季铵化的含氮杂环，或其 酯或其盐，其具有优异的抗细菌活性，稳定性，吸收性等，其生产和含有它的药物组合物。

公开(公告)号：US08219280B2

公开(公告)日：2012-07-10

申请号：US12741547

申请日：2008-12-04

申请人： Tomoyasu Ishikawa

发明人： Tomoyasu Ishikawa

IPC分类号： G01M17/00 ,  B60K1/00

CPC分类号： G07C5/085

摘要： A vehicle information storage apparatus capable of storing necessary information dataset helpful for diagnosis. The vehicle information storage apparatus includes a status information acquiring unit acquiring a dataset of status information items of a vehicle; and a controlling unit determining a time point when the malfunction started based on the dataset of status information items acquired by the status information acquiring unit, and further determines the malfunction-cause-investigation information data to be used for investigating the cause of the malfunction from among the dataset of status information items acquired by the status information acquiring unit based on the specified time point when the malfunction started, and stores the determined malfunction-cause-investigation information data in a prescribed storage medium.

摘要翻译： 一种能够存储有助于诊断的必要信息数据集的车辆信息存储装置。 车辆信息存储装置包括：状态信息获取单元，获取车辆的状态信息项的数据集; 以及控制单元，基于由状态信息获取单元获取的状态信息项的数据集来确定故障开始的时间点，并且还确定用于调查故障原因的故障原因调查信息数据 在状态信息获取单元基于所述故障开始时的指定时间点获取的状态信息项的数据集中，并将所确定的故障原因调查信息数据存储在规定的存储介质中。

公开(公告)号：US08178543B2

公开(公告)日：2012-05-15

申请号：US12172631

申请日：2008-07-14

申请人： Tomoyasu Ishikawa ,  Hiroshi Banno ,  Masaki Seto

发明人： Tomoyasu Ishikawa ,  Hiroshi Banno ,  Masaki Seto

IPC分类号： C07D487/04 ,  A61K31/519 ,  A61P35/00

CPC分类号： C07D487/04 ,  C07D487/16

摘要： The present invention relates to a compound represented by the formula: wherein W is C(R1) or N, each A is an optionally substituted aryl group or a heteroaryl group, X1 is —NR3—Y1—, —O—, —S—, —SO—, —SO2— or —CHR3— wherein R3 is a hydrogen atom or an optionally substituted aliphatic hydrocarbon group, or R3 is optionally bonded to A to form an optionally substituted ring structure, R1 is a hydrogen atom or an optionally substituted group bonded via a carbon atom, a nitrogen atom or an oxygen atom, R2 is a hydrogen atom or optionally substituted group bonded via a carbon atom or a sulfur atom, or R1 and R2, or R2 and R3 are optionally bonded to form an optionally substituted ring structure, or a salt thereof, and a tyrosine kinase inhibitor or an agent for the prophylaxis or treatment of cancer, which contains this compound or a prodrug thereof.

摘要翻译： 本发明涉及由下式表示的化合物：其中W是C（R 1）或N，每个A是任选取代的芳基或杂芳基，X 1是-NR 3 -Y 1 - ， - O - ， - ，-SO-，-SO 2 - 或-CHR 3 - ，其中R 3是氢原子或任选取代的脂族烃基，或R 3任选地键合到A上以形成任选取代的环结构，R 1是氢原子或任选被取代的 通过碳原子，氮原子或氧原子键合的基团，R 2是氢原子或经由碳原子或硫原子键合的任选取代的基团，或R 1和R 2，或R 2和R 3可任选地键合形成任选地 取代的环结构或其盐，以及含有该化合物或其前药的酪氨酸激酶抑制剂或用于预防或治疗癌症的药剂。

公开(公告)号：US08116934B2

公开(公告)日：2012-02-14

申请号：US12467476

申请日：2009-05-18

申请人： Tomoyasu Ishikawa

发明人： Tomoyasu Ishikawa

IPC分类号： G06F19/00

CPC分类号： G07C5/008

摘要： A vehicle failure analysis system for a vehicle equipped with a plurality of control systems, each of which includes one or more components, includes: a faulty system identification unit that identifies a faulty control system from among the plurality of control systems; and a faulty component identification unit that identifies a faulty component from among the one or more components which are constituents of the identified control system.

摘要翻译： 一种配备有多个控制系统的车辆的车辆故障分析系统，每个控制系统包括一个或多个组件，包括：错误的系统识别单元，其从多个控制系统中识别故障控制系统; 以及故障组件识别单元，其从所述一个或多个组件中识别故障组件，所述组件是所识别的控制系统的组成部分。

公开(公告)号：US20100268415A1

公开(公告)日：2010-10-21

申请号：US12741547

申请日：2008-12-04

申请人： Tomoyasu Ishikawa

发明人： Tomoyasu Ishikawa

IPC分类号： G07C5/08

CPC分类号： G07C5/085

摘要： A vehicle information storage apparatus capable of storing necessary information dataset helpful for diagnosis. The vehicle information storage apparatus includes a status information acquiring unit acquiring a dataset of status information items of a vehicle; and a controlling unit determining a time point when the malfunction started based on the dataset of status information items acquired by the status information acquiring unit, and further determines the malfunction-cause-investigation information data to be used for investigating the cause of the malfunction from among the dataset of status information items acquired by the status information acquiring unit based on the specified time point when the malfunction started, and stores the determined malfunction-cause-investigation information data in a prescribed storage medium.

摘要翻译： 一种能够存储有助于诊断的必要信息数据集的车辆信息存储装置。 车辆信息存储装置包括：状态信息获取单元，获取车辆的状态信息项的数据集; 以及控制单元，基于由状态信息获取单元获取的状态信息项的数据集来确定故障开始的时间点，并且还确定用于调查故障原因的故障原因调查信息数据 在状态信息获取单元基于所述故障开始时的指定时间点获取的状态信息项的数据集中，并将所确定的故障原因调查信息数据存储在规定的存储介质中。

公开(公告)号：US20100004238A1

公开(公告)日：2010-01-07

申请号：US12518596

申请日：2007-12-11

申请人： Tomoyasu Ishikawa ,  Hiroshi Banno ,  Youichi Kawakita ,  Tomohiro Ohashi ,  Osamu Kurasawa

发明人： Tomoyasu Ishikawa ,  Hiroshi Banno ,  Youichi Kawakita ,  Tomohiro Ohashi ,  Osamu Kurasawa

IPC分类号： A61K31/5377 ,  C07D487/04 ,  A61K31/519 ,  A61K31/4985

CPC分类号： C07D487/04

摘要： The present invention provides a fused heterocyclic compound having a tyrosine kinase inhibitory action, which is represented by the formula: wherein R1 is a hydrogen atom, a halogen atom, or an optionally substituted group bonded via a carbon atom, a nitrogen atom or an oxygen atom; R2 is a hydrogen atom, or an optionally substituted group bonded via a carbon atom or a sulfur atom, or R1 and R2, or R2 and R3 are optionally bonded to each other to form an optionally substituted ring structure; R3 is a hydrogen atom or an optionally substituted aliphatic hydrocarbon group, or R3 is optionally bonded to the carbon atom on ring A to form an optionally substituted ring structure; ring A is an optionally substituted benzene ring; and ring B is (i) an optionally substituted fused ring, or (ii) a pyridine ring having optionally substituted carbamoyl (the pyridine ring is optionally further substituted).

摘要翻译： 本发明提供具有酪氨酸激酶抑制作用的稠合杂环化合物，其由下式表示：其中R1是氢原子，卤原子或经由碳原子，氮原子或氧键键合的任意取代的基团 原子; R2是氢原子，或通过碳原子或硫原子键合的任选取代的基团，或者R 1和R 2，或R 2和R 3相互结合形成任选取代的环结构; R3是氢原子或任选取代的脂族烃基，或R3任选地键合到环A上的碳原子上以形成任选取代的环结构; 环A是任选取代的苯环; 和环B是（i）任选取代的稠合环，或（ii）具有任选取代的氨基甲酰基的吡啶环（吡啶环任选进一步被取代）。