公开(公告)号：US07087628B2

公开(公告)日：2006-08-08

申请号：US10264997

申请日：2002-10-04

申请人： Zhihua Sui ,  Mark Macielag ,  James Lanter

发明人： Zhihua Sui ,  Mark Macielag ,  James Lanter

IPC分类号： A61K31/4439 ,  C07D401/12

CPC分类号： C07D401/12 ,  A61K31/38 ,  A61K31/415 ,  A61K31/435 ,  A61K31/44 ,  A61K31/47 ,  C07D409/14 ,  C07D471/04

摘要： This invention relates to a series of N-heterocyclyl hydrazides of Formula I, and pharmaceutical compositions containing them. The compounds of the invention have neurotrophic activity and are useful in the treatment and prevention of neuronal disorders such as Parkinson's disease, Alzheimer's disease, stroke, multiple sclerosis, amyotrophic lateral sclerosis diabetic neuropathy and Bell's palsy.

公开(公告)号：US20060063819A1

公开(公告)日：2006-03-23

申请号：US11223187

申请日：2005-09-09

申请人： James Lanter ,  Zhihua Sui

发明人： James Lanter ,  Zhihua Sui

IPC分类号： C07D233/70 ,  A61K31/4166

CPC分类号： C07D233/34

摘要： The present invention is directed to novel imidazolidin-2-one derivatives having a structure according to Formula I wherein a, b, R1, R2, R3, and R4 are as defined above, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.

摘要翻译： 本发明涉及具有式I结构的新的咪唑烷-2-酮衍生物

公开(公告)号：US20050245485A1

公开(公告)日：2005-11-03

申请号：US11096664

申请日：2005-04-01

申请人： James Lanter ,  Zhihua Sui ,  James Fiordeliso ,  Weiqin Jiang ,  Xuqing Zhang

发明人： James Lanter ,  Zhihua Sui ,  James Fiordeliso ,  Weiqin Jiang ,  Xuqing Zhang

IPC分类号： A61K31/343 ,  A61K31/381 ,  A61K31/405 ,  A61K31/695 ,  C07D401/04 ,  C07D409/04

CPC分类号： C07D209/12 ,  C07D401/04 ,  C07D409/04

摘要： The present invention is directed to novel indole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.

摘要翻译： 本发明涉及新的吲哚衍生物，含有它们的药物组合物及其用于治疗由雄激素受体调节的病症和状况。