-
公开(公告)号:US20120122951A1
公开(公告)日:2012-05-17
申请号:US13138787
申请日:2010-03-04
申请人: Rikako Suzuki , Yosuke Tojo , Chieko Mizumoto , Kiyotaka Hasegawa , Yutaka Ashida , Jun-ichi Hosoi , Kiyoshi Sato
发明人: Rikako Suzuki , Yosuke Tojo , Chieko Mizumoto , Kiyotaka Hasegawa , Yutaka Ashida , Jun-ichi Hosoi , Kiyoshi Sato
IPC分类号: A61K31/40 , A61Q19/02 , C07D207/16
CPC分类号: A61K31/401 , A23L33/175 , A23V2002/00 , A61K8/0212 , A61K8/0216 , A61K8/4913 , A61K2800/92 , A61Q19/02 , A23V2200/318
摘要: The development of a skin-whitening agent which has a lower molecular weight, can be synthesized through a fewer steps and can be produced at low cost has been demanded. Thus, it is provided by the present invention a skin-whitening agent including one or more compounds selected from the group consisting of 4-cis-hydroxyproline and its derivative and/or its salt, a skin-whitening composition for external formulation to the skin, a cosmetic composition and a pharmaceutical composition, each of which contains the skin-whitening agent of the invention, and a cosmetic method for whitening the skin, which includes a step of administering one or more compounds selected from the group consisting of 4-cis-hydroxyproline and its derivative and/or its salt. In the skin-whitening agent and the cosmetic method for whitening the skin of the invention, the 4-cis-hydroxyproline may be 4-cis-L-hydroxyproline and/or 4-cis-D-hydroxyproline.
摘要翻译: 需要开发具有较低分子量的皮肤增白剂,可以通过较少的步骤合成并且可以以低成本生产。 因此,本发明提供一种皮肤增白剂,其包含一种或多种选自4-顺式 - 羟基脯氨酸及其衍生物和/或其盐的化合物,用于皮肤外用制剂的皮肤增白组合物 ,化妆品组合物和药物组合物,其含有本发明的皮肤增白剂和美白化妆品的方法,其包括给予一种或多种选自4-顺式 - 羟脯氨酸及其衍生物和/或其盐。 在本发明的皮肤美白剂和美白化妆品的美白方法中,4-顺式 - 羟基脯氨酸可以是4-顺式-L-羟基脯氨酸和/或4-顺式-D-羟基脯氨酸。
-
公开(公告)号:US08586622B2
公开(公告)日:2013-11-19
申请号:US13261241
申请日:2010-05-14
申请人: Yosuke Tojo , Jun-ichi Hosoi , Kayo Matsumoto
发明人: Yosuke Tojo , Jun-ichi Hosoi , Kayo Matsumoto
IPC分类号: A01N43/36
CPC分类号: A21D2/245 , A23C9/1322 , A23G3/34 , A23G3/44 , A23L7/20 , A23L11/09 , A23L27/50 , A23L27/60 , A23L33/175 , A23V2002/00 , A61K8/35 , A61K8/44 , A61K8/4913 , A61K31/198 , A61K31/401 , A61Q19/00 , A61Q19/08 , A23V2200/318 , A23V2250/0604
摘要: Disclosed is a novel composition which has a function of stimulating production of laminin-332. The composition is stable and safe, and can be used routinely. Specifically disclosed is a laminin-332 production stimulating composition which contains one or more compounds selected from the group consisting of D-alanine, D-hydroxyproline, derivatives and/or salts thereof. The composition may be used for the purpose of suppressing and/or improving a skin condition. The skin condition may include, but is not limited to a photoaging, wrinkles, a rough skin, fine wrinkles and a dry skin. The composition may be used for an external preparation for the skin or a food.
摘要翻译: 公开了具有刺激层粘连蛋白-33的产生的功能的新型组合物。 组合物稳定安全,可以常规使用。 具体公开的是含有一种或多种选自D-丙氨酸,D-羟脯氨酸,其衍生物和/或盐的化合物的层粘连蛋白-33生产刺激组合物。 该组合物可以用于抑制和/或改善皮肤状况。 皮肤状况可以包括但不限于光老化,皱纹,粗糙的皮肤,细小的皱纹和干燥的皮肤。 该组合物可用于皮肤或食物的外用制剂。
-
公开(公告)号:US20120184593A1
公开(公告)日:2012-07-19
申请号:US13261241
申请日:2010-05-14
申请人: Yosuke Tojo , Jun-ichi Hosoi , Kayo Matsumoto
发明人: Yosuke Tojo , Jun-ichi Hosoi , Kayo Matsumoto
IPC分类号: A61K31/401 , A61P17/00 , A61K31/198
CPC分类号: A21D2/245 , A23C9/1322 , A23G3/34 , A23G3/44 , A23L7/20 , A23L11/09 , A23L27/50 , A23L27/60 , A23L33/175 , A23V2002/00 , A61K8/35 , A61K8/44 , A61K8/4913 , A61K31/198 , A61K31/401 , A61Q19/00 , A61Q19/08 , A23V2200/318 , A23V2250/0604
摘要: Disclosed is a novel composition which has a function of stimulating production of laminin-332. The composition is stable and safe, and can be used routinely. Specifically disclosed is a laminin-332 production stimulating composition which contains one or more compounds selected from the group consisting of D-alanine, D-hydroxyproline, derivatives and/or salts thereof. The composition may be used for the purpose of suppressing and/or improving a skin condition. The skin condition may include, but is not limited to a photoaging, wrinkles, a rough skin, fine wrinkles and a dry skin. The composition may be used for an external preparation for the skin or a food.
摘要翻译: 公开了具有刺激层粘连蛋白-33的产生的功能的新型组合物。 组合物稳定安全,可以常规使用。 具体公开的是含有一种或多种选自D-丙氨酸,D-羟脯氨酸,其衍生物和/或盐的化合物的层粘连蛋白-33生产刺激组合物。 该组合物可以用于抑制和/或改善皮肤状况。 皮肤状况可以包括但不限于光老化,皱纹,粗糙的皮肤,细小的皱纹和干燥的皮肤。 该组合物可用于皮肤或食物的外用制剂。
-
-