公开(公告)号：US20210128925A1

公开(公告)日：2021-05-06

申请号：US17086127

申请日：2020-10-30

Applicant: Medtronic, Inc.

Inventor： Subham Ghosh ,  Tarek D. Haddad ,  Marc C. Steckler ,  Karen J. Kleckner ,  Elizabeth A. Schotzko

IPC: A61N1/365 ,  A61N1/368 ,  A61N1/37

Abstract: Systems and methods are described herein for evaluation and adjustment cardiac therapy. The systems and methods may initially evaluate a first pacing parameter while other pacing parameters are fixed to, for example, nominal values, and determine an effective setting for the first pacing parameter. Then, a second pacing parameter may be evaluated while the first pacing parameter is fixed to the previously-determined effective setting. Each evaluation may not test every possible setting for the pacing parameters, and instead, may utilize various processes to limit the settings to a subset of settings to test.

公开(公告)号：US10918870B2

公开(公告)日：2021-02-16

申请号：US15914396

申请日：2018-03-07

Applicant: Medtronic, Inc.

Inventor： Subham Ghosh ,  Zhongping Yang

IPC: A61N1/37 ,  A61N1/39 ,  A61N1/372 ,  A61N1/05 ,  A61N1/368 ,  A61B5/00 ,  A61B5/0456 ,  A61B5/0408 ,  A61B5/0428 ,  A61B5/0452

Abstract: A system and method of positioning an atrial pacing lead for delivery of a cardiac pacing therapy that includes sensing electrical activity of tissue of a patient from a plurality of external electrodes and determining a distribution of bi-atrial activation in response to the sensed electrical activity. A target site for delivering the atrial pacing therapy is adjusted based on a change in bi-atrial dyssynchrony that is determined in response to the determined distribution of bi-atrial activation, and placement of the atrial pacing lead for delivery of the atrial pacing therapy is determined in response to the adjusting.

公开(公告)号：US10881862B2

公开(公告)日：2021-01-05

申请号：US15975258

申请日：2018-05-09

Applicant: Medtronic, Inc.

Inventor： Subham Ghosh

IPC: A61N1/368 ,  A61N1/365 ,  A61N1/39 ,  A61N1/375 ,  A61N1/05 ,  A61N1/37 ,  A61N1/362

Abstract: Methods and/or devices may be configured to estimate right ventricular-timings from left ventricular (LV) sensing times for adaptive cardiac therapy using DDD/VDD LV pacing without using a right ventricular (RV) lead. One embodiment employs a subcutaneous device (SD) in a patient and a leadless pacing device (LPD) coupled to a patient's heart. Heart activity including atrial and ventricular events are sensed from the patient's heart using the SD. Left ventricular events (LVS) are sensed using the LPD. The SD is used to determine whether cardiac resynchronization pacing therapy (CRT pacing) is appropriate based upon the heart activity sensed by the SD. The SD is further configured to determine timing of CRT pacing pulses for delivery to cardiac tissue through the LPD.

公开(公告)号：US20200306546A1

公开(公告)日：2020-10-01

申请号：US16370203

申请日：2019-03-29

Applicant: Medtronic, Inc.

Inventor： Subham Ghosh

IPC: A61N1/37 ,  A61B5/0408 ,  A61B5/042

Abstract: Systems, methods, and devices are described herein for determining cardiac conduction system capture of ventricle from atrium (VfA) therapy. VfA therapy may be delivered at a plurality of different A-V delays while electrical activity of the patient is monitored. The electrical activity may then be utilized to determine whether the cardiac conduction system of the patient has been captured by the VfA therapy.

公开(公告)号：US10786167B2

公开(公告)日：2020-09-29

申请号：US15853160

申请日：2017-12-22

Applicant: Medtronic, Inc.

Inventor： Subham Ghosh

IPC: A61B5/04 ,  A61B5/0408 ,  A61N1/365 ,  A61B5/00 ,  A61N1/37 ,  A61B5/0468 ,  A61N1/372 ,  A61N1/362

Abstract: The exemplary systems and methods may be configured for use in the determination of ectopic beat-compensated electrical heterogeneity information. Electrical activity can be monitored by a plurality of external electrodes. Ectopic beat information can be detected. Ectopic beat-compensated electrical heterogeneity information can be generated based on the monitored electrical activity and the detected ectopic beat information.

公开(公告)号：US20200289829A1

公开(公告)日：2020-09-17

申请号：US16793193

申请日：2020-02-18

Applicant: Medtronic, Inc.

Inventor： Subham Ghosh

IPC: A61N1/365 ,  A61N1/362 ,  A61N1/368 ,  A61N1/37 ,  A61N1/39

Abstract: An implantable medical device includes a plurality of electrodes to detect electrical activity, a motion detector to detect mechanical activity, and a controller to determine at least one electromechanical interval based on at least one of electrical activity and mechanical activity. The activity detected may be in response to delivering a pacing pulse according to an atrioventricular (AV) pacing interval using the second electrode. The electromechanical interval may be used to adjust the AV pacing interval. The electromechanical interval may be used to determine whether cardiac therapy is acceptable or whether atrial or ventricular remodeling is successful.

公开(公告)号：US10596383B2

公开(公告)日：2020-03-24

申请号：US15944050

申请日：2018-04-03

Applicant: Medtronic, Inc.

Inventor： Subham Ghosh

IPC: A61N1/368 ,  A61N1/375 ,  A61N1/37 ,  A61N1/365 ,  A61N1/362 ,  A61N1/39 ,  A61N1/05 ,  A61N1/372

Abstract: A method and system that includes an implantable cardioverter defibrillator (ICD) determining signal characteristics of a cardiac signal within a signal evaluation window positioned along a first portion of a cardiac cycle and determining whether a P-wave occurs within the signal evaluation window associated with the first portion of the cardiac cycle. The signal evaluation window is adjusted to be positioned along a second portion of the cardiac cycle in response to the P-wave not occurring within the signal evaluation window and signal characteristics of the cardiac signal are determined within the adjusted signal evaluation window. A determination is made as to whether a P-wave occurs in response to the signal characteristics determined within the adjusted signal evaluation window, and the ICD delivers a trigger signal to a leadless pacing device instructing delivery of ventricular pacing therapy by the leadless pacing device whenever a P-wave is determined to occur.

公开(公告)号：US10512781B2

公开(公告)日：2019-12-24

申请号：US15989927

申请日：2018-05-25

Applicant: Medtronic, Inc.

Inventor： Robert W. Stadler ,  Subham Ghosh

IPC: A61N1/37 ,  A61B5/046 ,  A61N1/362 ,  A61N1/368

Abstract: The present disclosure relates to cardiac evoked response detection and, more particularly, reducing polarization effects in order to detect an evoked response following delivery of a stimulation pulse. An implantable medical device (IMD) is configured to deliver a ventricular pacing pulse. A signal is sensed in response to the ventricular pacing stimulus. A window is placed over the sensed signal to obtain a set of data from the signal after a paced event. The set of data extracted from the sensed signal comprises a maximum amplitude, a maximum time associated with the maximum amplitude, a minimum amplitude, and a minimum time associated with the minimum amplitude. Responsive to processing the extracted data, the window is delayed to avoid polarization effects. A determination is then made as to whether the ventricular pacing stimulus is capturing the paced ventricle in response to determining whether the maximum time is greater than the minimum time.

公开(公告)号：US20190290905A1

公开(公告)日：2019-09-26

申请号：US16362015

申请日：2019-03-22

Applicant: Medtronic, Inc.

Inventor： Zhongping Yang ,  Subham Ghosh

IPC: A61N1/362 ,  A61B5/042 ,  A61N1/05 ,  A61N1/365 ,  A61N1/39 ,  A61N1/375

Abstract: VfA cardiac therapy uses an implantable medical device or system. The implantable medical device includes a tissue-piercing electrode implanted in the basal and/or septal region of the left ventricular myocardium of the patient's heart from the triangle of Koch region of the right atrium through the right atrial endocardium and central fibrous body. The device may include a right atrial electrode, a right atrial motion detector, or both. The device may be implanted completely within the patient's heart or may use one or more leads to implant electrodes in the patient's heart. The device may be used to provide cardiac therapy, including single or multiple chamber pacing, atrioventricular synchronous pacing, asynchronous pacing, triggered pacing, cardiac resynchronization pacing, or tachycardia-related therapy. A separate medical device may be used to provide some functionality for cardiac therapy, such as sensing, pacing, or shock therapy.

公开(公告)号：US10368766B2

公开(公告)日：2019-08-06

申请号：US15095661

申请日：2016-04-11

Applicant: Medtronic, Inc.

Inventor： Jeffrey Gillberg ,  Subham Ghosh

IPC: A61B5/0408 ,  A61B5/04 ,  A61B5/00

Abstract: Various embodiments of a bioelectric sensor device for sensing bioelectric data from a human body are disclosed. The device can include a flexible substrate, a plurality of sensors arranged in a sensor array on a sensor array portion of the substrate, an electrically conductive network located on the substrate, and a plurality of lines of weakness formed in the sensor array portion of the substrate. In one or more embodiments, each line of weakness is configured to enhance separation of the sensor array portion of the substrate along a separation line that extends between at least two sensors of the plurality of sensors. The device can also include a left reference electrode proximate a distal end of a left reference electrode arm of the substrate and a right reference electrode proximate a distal end of a right reference electrode arm of the substrate.