公开(公告)号：US20220202491A1

公开(公告)日：2022-06-30

申请号：US17135022

申请日：2020-12-28

Applicant: ADVANCED NEUROMODULATION SYSTEMS, INC.

Inventor： Yagna Pathak ,  Simeng Zhang ,  Dehan Zhu ,  Anahita Kyani ,  Hyun-Joo Park ,  Erika Ross

IPC: A61B34/10 ,  G06K9/32 ,  G06K9/62 ,  G06T7/70 ,  G06T7/00 ,  A61B6/03 ,  A61B6/00 ,  A61B5/055 ,  G06N3/08 ,  G16H30/40

Abstract: A system and method for facilitating DBS electrode trajectory planning using a machine learning (ML)-based feature identification scheme configured to identify and distinguish between various regions of interest (ROIs) and regions of avoidance (ROAs) in a patient's brain scan image. In one arrangement, standard orientation image slices as well as re-sliced images in non-standard orientations are provided in a labeled input dataset for training a CNN/ANN for distinguishing between ROIs and ROAs. Upon identification of the ROIs and ROAs in the patient's brain scan image, an optimal trajectory for implanting a DBS lead may be determined relative to a particular ROI while avoiding any ROAs.

公开(公告)号：US20220193423A1

公开(公告)日：2022-06-23

申请号：US17214513

申请日：2021-03-26

Applicant: Advanced Neuromodulation Systems, Inc.

Inventor： Syed Askari-Raza Baqar ,  Robert Jones

IPC: A61N1/375 ,  H01R13/52 ,  H01R13/627

Abstract: An implantable pulse generator includes a housing component containing electrical circuitry for generating electrical pulses and a header component connected to the housing component. The header component is adapted to connect to one or more stimulation leads for applying the electrical pulses to the tissue of the patient. The header includes a locking member for an electrical terminal of the implantable pulse generator. The locking member includes a head, an elongate body portion adjacent the head and has a proximal section with a first diameter and a distal section having a second diameter. A transition section is between the proximal section and the distal section. The transition section smoothly transitions from the first diameter to the second diameter. The elongate body portion is configured to provide an interference fit to the electrical terminal in a locked position and hold the electrical terminal in place.

公开(公告)号：US20220088376A1

公开(公告)日：2022-03-24

申请号：US17541531

申请日：2021-12-03

Applicant: ADVANCED NEUROMODULATION SYSTEMS, INC.

Inventor： Jodi T. Dubuclet ,  Cory Brinkman

IPC: A61N1/05

Abstract: Stimulation lead includes an elongated lead body having distal and proximal ends and wire conductors extending therebetween. The stimulation lead also includes a lead paddle having a multi-dimensional array of electrodes positioned along a contact side of the lead paddle. The electrodes are electrically coupled to the wire conductors. The lead paddle includes a paddle body and a conductor organizer disposed within the paddle body. The conductor organizer has multiple channels extending along the lead paddle. The channels receive the wire conductors and retain the wire conductors in a designated arrangement with respect to the lead paddle. The conductor organizer has openings to the channels. The wire conductors extend through the openings and are terminated to the respective electrodes.

公开(公告)号：US20220072315A1

公开(公告)日：2022-03-10

申请号：US17082299

申请日：2020-10-28

Applicant: Advanced Neuromodulation Systems, Inc.

Inventor： Simeng Zhang ,  Hyun-Joo Park ,  Filippo Agnesi ,  Yagna Pathak ,  Erika Ross

IPC: A61N1/36 ,  A61N1/05

Abstract: The present disclosure provides systems and methods for generating burst waveforms. An implantable neurostimulation system includes an implantable stimulation lead including a plurality of contacts, and an implantable pulse generator communicatively coupled to the stimulation lead. The pulse generator is configured to generate a waveform including a burst that includes a leading anodic pulse followed by alternating cathodic pulses and anodic pulses, each cathodic pulse in the burst having a greater amplitude than the previous cathodic pulse.

公开(公告)号：US20210402192A1

公开(公告)日：2021-12-30

申请号：US17447272

申请日：2021-09-09

Applicant: ADVANCED NEUROMODULATION SYSTEMS, INC.

Inventor： Daran DeShazo ,  Steven Boor ,  Vidhi Desai

IPC: A61N1/372 ,  A61N1/36 ,  A61N1/05

Abstract: Embodiments are directed to an implantable medical device comprising therapeutic stimulation circuitry for controlling delivery of a medical therapy to a patient, the therapeutic stimulation circuitry having at least one lead having electrodes for delivering the medical therapy, The implantable medical device further comprises measurement circuitry for determining characteristics of the at least one lead, a processor for controlling the IMD according to executable code, and memory for storing data and executable code, wherein the executable code comprises instructions for causing the processor to receive a plurality of voltage measurements associated with the electrodes, and calculate values for an impedance model of the electrode/tissue interface.

公开(公告)号：US20210370077A1

公开(公告)日：2021-12-02

申请号：US17399167

申请日：2021-08-11

Applicant: Advanced Neuromodulation Systems, Inc.

Inventor： Christopher S. L. CRAWFORD

IPC: A61N1/372

Abstract: In one embodiment, an implantable medical device (IMD) comprises: therapeutic circuitry for controlling delivery of a medical therapy to a patient; a processor for controlling the IMD according to executable code; wireless communication circuitry for conducting wireless communications; and memory for storing data and executable code, wherein the executable comprises code for causing the processor to (1) communicate with an external programming device to define therapeutic settings for operation of the IMD, (2) perform validation operations on one or more instances of therapeutic settings by determining whether a respective instance of therapeutic settings is accompanied by permanent validation data or temporary validation data, wherein the validation operations comprise analyzing temporary validation data against at least one key of a plurality of cryptographic keys stored by the IMD.

公开(公告)号：US11173311B2

公开(公告)日：2021-11-16

申请号：US16179716

申请日：2018-11-02

Applicant: Advanced Neuromodulation Systems, Inc

Inventor： Christopher S. L. Crawford

IPC: A61N1/372 ,  G16H20/40 ,  G16H20/17 ,  A61N1/36 ,  A61N1/362 ,  A61N1/02 ,  A61M5/142 ,  A61M5/172 ,  A61N1/05

Abstract: In one embodiment, a method of programming an implantable medical device (IMD) to provide therapeutic operations for a patient, comprises: conducting a first communication session between the IMD with an external programming device when network connectivity for a remote server for medical device management is not available for the external programming device; receiving programming data by the IMD from the external programming device to provide therapeutic operations according to at least one instance of settings data during the first communication session, wherein the at least one instance of settings data is validated by a temporary key; conducting a second communication session between the IMD with an external device when network connectivity to the remote server for medical device management is available for the external device; and replacing validation data signed using the temporary key with the received validation data.

公开(公告)号：US20210339016A1

公开(公告)日：2021-11-04

申请号：US16864317

申请日：2020-05-01

Applicant: Advanced Neuromodulation Systems, Inc.

Inventor： Matthew K. Dion

IPC: A61N1/05

Abstract: In one embodiment, a system for stimulating the dorsal root ganglion of a patient comprises an elongate flexible implantable stimulation lead adapted to apply the stimulation pulses to the dorsal root ganglion of the patient, wherein the distal end comprises at least one electrode. A first segment and a second segment of the anchor are configured to transition between a collapsed configuration and deployed configuration. A central channel in the first segment and the second segment allows the anchor to be advanced along the stimulation lead from a proximal end toward the distal end while in the collapsed configuration. The central channel of each segment grips onto the stimulation lead in the deployed configuration so that the segment does not move from a deployed position on the stimulation lead. The first segment and the second segment may be deployed on opposite sides of foraminal ligament to anchor the stimulation lead.

公开(公告)号：US11135439B2

公开(公告)日：2021-10-05

申请号：US16370357

申请日：2019-03-29

Applicant: ADVANCED NEUROMODULATION SYSTEMS, INC.

Inventor： Daran DeShazo ,  Steven Boor ,  Vidhi Desai

IPC: A61N1/372 ,  A61N1/36 ,  A61N1/05

Abstract: Embodiments are directed to an implantable medical device comprising therapeutic stimulation circuitry for controlling delivery of a medical therapy to a patient, the therapeutic stimulation circuitry having at least one lead having electrodes for delivering the medical therapy. The implantable medical device further comprises measurement circuitry for determining characteristics of the at least one lead, a processor for controlling the IMD according to executable code, and memory for storing data and executable code, wherein the executable code comprises instructions for causing the processor to receive a plurality of voltage measurements associated with the electrodes, and calculate values for an impedance model of the electrode/tissue interface.

公开(公告)号：US11135434B2

公开(公告)日：2021-10-05

申请号：US16433975

申请日：2019-06-06

Applicant: ADVANCED NEUROMODULATION SYSTEMS, INC.

Inventor： Steven Boor

IPC: A61N1/37 ,  A61N1/372 ,  A61N1/39 ,  A61N1/02

Abstract: The present disclosure provides systems and methods for protection circuitry for an implantable pulse generator (IPG) of a neurostimulation system. The protection circuitry is coupled to an IPG ground, a plurality of electrodes, and an IPG case, and operable to protect IPG stimulation and sensing circuitry from damage during electrostatic discharge and cardiac defibrillation, and to mitigate unintended stimulation during electromagnetic interference. The protection circuitry includes an IPG ground connection, a plurality of protection Zener diodes, wherein one of the protection Zener diodes is electrically coupled between the IPG case and a float Zener diode, and wherein the remaining protection Zener diodes are electrically coupled between the plurality of electrodes and the float Zener diode, and the float Zener diode electrically coupled between the plurality of protection Zener diodes and the IPG ground.