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1.发明授权公开(公告)号：US11964152B2
公开(公告)日：2024-04-23
申请号：US16404517
申请日：2019-05-06
Applicant: ADVANCED NEUROMODULATION SYSTEMS, INC.
Inventor： Filippo Agnesi , Lalit Venkatesan , Christopher S. L. Crawford
CPC classification number: A61N1/36071 , A61N1/06 , A61N1/36062 , A61N1/36167 , A61N1/37247
Abstract: This application is generally related to identifying or otherwise programming one or more cycling parameters for operation of an implantable pulse generator to provide a neurostimulation therapy to a patient using a non-paresthesia stimulation pattern. In some embodiments, the cycling parameter is selected by measuring physiological signals during trial stimulation. In other embodiments, multiple cycling parameters are identified for use by the patient using a patient controller device.
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公开(公告)号：US11957913B2
公开(公告)日：2024-04-16
申请号：US18143206
申请日：2023-05-04
Applicant: Advanced Neuromodulation Systems, Inc.
Inventor： Simeng Zhang , Hyun-Joo Park , Filippo Agnesi , Yagna Pathak , Erika Ross
CPC classification number: A61N1/36178 , A61N1/0551 , A61N1/36175 , A61N1/36071
Abstract: The present disclosure provides systems and methods for generating burst waveforms. An implantable neurostimulation system includes an implantable stimulation lead including a plurality of contacts, and an implantable pulse generator communicatively coupled to the stimulation lead. The pulse generator is configured to generate a waveform including a burst that includes a leading anodic pulse followed by alternating cathodic pulses and anodic pulses, each cathodic pulse in the burst having a greater amplitude than the previous cathodic pulse.
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公开(公告)号：US20240390682A1
公开(公告)日：2024-11-28
申请号：US18609736
申请日：2024-03-19
Applicant: Advanced Neuromodulation Systems, Inc.
Inventor： Simeng Zhang , Hyun-Joo Park , Filippo Agnesi , Yagna Pathak , Erika Ross
Abstract: The present disclosure provides systems and methods for generating burst waveforms. An implantable neurostimulation system includes an implantable stimulation lead including a plurality of contacts, and an implantable pulse generator communicatively coupled to the stimulation lead. The pulse generator is configured to generate a waveform including a burst that includes a leading anodic pulse followed by alternating cathodic pulses and anodic pulses, each cathodic pulse in the burst having a greater amplitude than the previous cathodic pulse.
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公开(公告)号：US11759643B2
公开(公告)日：2023-09-19
申请号：US17008869
申请日：2020-09-01
Applicant: ADVANCED NEUROMODULATION SYSTEMS, INC.
Inventor： Filippo Agnesi
CPC classification number: A61N1/37247 , A61N1/0534 , A61N1/0551 , A61N1/36067 , A61N1/36167 , A61N1/0476 , A61N1/0509 , A61N1/0512 , A61N1/0514 , A61N1/0524 , A61N1/0531 , A61N1/0553 , A61N1/362 , A61N1/36062 , A61N1/36125 , A61N1/36132 , A61N1/36135 , A61N1/36171 , A61N1/36175 , A61N1/36178 , A61N1/36185 , G16H20/40
Abstract: The systems and methods described herein generally relate to adjusting a neurostimulation (NS) therapy based on drug pharmacokinetics of a patient. The systems and methods deliver an NS therapy to a portion of electrodes of a lead positioned proximate to neural tissue of interest, which is associated with a target region. The NS therapy is defined by stimulation parameters. The systems and methods determine a trigger event indicative of a drug being administered to a patient. The drug is configured to affect at least one of the neural tissue of interest or the target region. The systems and methods adjust one or more of the stimulation parameters based on the PS profile.
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公开(公告)号：US11679264B2
公开(公告)日：2023-06-20
申请号：US17082299
申请日：2020-10-28
Applicant: Advanced Neuromodulation Systems, Inc.
Inventor： Simeng Zhang , Hyun-Joo Park , Filippo Agnesi , Yagna Pathak , Erika Ross
CPC classification number: A61N1/36178 , A61N1/0551 , A61N1/36175 , A61N1/36071
Abstract: The present disclosure provides systems and methods for generating burst waveforms. An implantable neurostimulation system includes an implantable stimulation lead including a plurality of contacts, and an implantable pulse generator communicatively coupled to the stimulation lead. The pulse generator is configured to generate a waveform including a burst that includes a leading anodic pulse followed by alternating cathodic pulses and anodic pulses, each cathodic pulse in the burst having a greater amplitude than the previous cathodic pulse.
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Patent Agency Ranking
公开(公告)号：US20230372717A1
公开(公告)日：2023-11-23
申请号：US18230787
申请日：2023-08-07
Applicant: ADVANCED NEUROMODULATION SYSTEMS, INC.
Inventor： Filippo Agnesi
CPC classification number: A61N1/37247 , A61N1/36067 , A61N1/0551 , A61N1/0534 , A61N1/36167 , A61N1/36185 , A61N1/36175 , A61N1/36135 , A61N1/36132 , A61N1/36125 , A61N1/36062 , A61N1/0512 , A61N1/0509 , A61N1/0514 , A61N1/36171 , A61N1/36178 , A61N1/0553 , A61N1/362
Abstract: The systems and methods described herein generally relate to adjusting a neurostimulation (NS) therapy based on drug pharmacokinetics of a patient. The systems and methods deliver an NS therapy to a portion of electrodes of a lead positioned proximate to neural tissue of interest, which is associated with a target region. The NS therapy is defined by stimulation parameters. The systems and methods determine a trigger event indicative of a drug being administered to a patient. The drug is configured to affect at least one of the neural tissue of interest or the target region. The systems and methods adjust one or more of the stimulation parameters based on the PS profile.
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7.发明申请公开(公告)号：US20250099765A1
公开(公告)日：2025-03-27
申请号：US18644067
申请日：2024-04-23
Applicant: Advanced Neuromodulation Systems, Inc.
Inventor： Filippo Agnesi , Lalit Venkatesan , Christopher S. L. Crawford
Abstract: This application is generally related to identifying or otherwise programming one or more cycling parameters for operation of an implantable pulse generator to provide a neurostimulation therapy to a patient using a non-paresthesia stimulation pattern. In some embodiments, the cycling parameter is selected by measuring physiological signals during trial stimulation. In other embodiments, multiple cycling parameters are identified for use by the patient using a patient controller device.
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公开(公告)号：US20230271014A1
公开(公告)日：2023-08-31
申请号：US18143206
申请日：2023-05-04
Applicant: Advanced Neuromodulation Systems, Inc.
Inventor： Simeng Zhang , Hyun-Joo Park , Filippo Agnesi , Yagna Pathak , Erika Ross
CPC classification number: A61N1/36178 , A61N1/36175 , A61N1/0551 , A61N1/36071
Abstract: The present disclosure provides systems and methods for generating burst waveforms. An implantable neurostimulation system includes an implantable stimulation lead including a plurality of contacts, and an implantable pulse generator communicatively coupled to the stimulation lead. The pulse generator is configured to generate a waveform including a burst that includes a leading anodic pulse followed by alternating cathodic pulses and anodic pulses, each cathodic pulse in the burst having a greater amplitude than the previous cathodic pulse.
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公开(公告)号：US20220072315A1
公开(公告)日：2022-03-10
申请号：US17082299
申请日：2020-10-28
Applicant: Advanced Neuromodulation Systems, Inc.
Inventor： Simeng Zhang , Hyun-Joo Park , Filippo Agnesi , Yagna Pathak , Erika Ross
Abstract: The present disclosure provides systems and methods for generating burst waveforms. An implantable neurostimulation system includes an implantable stimulation lead including a plurality of contacts, and an implantable pulse generator communicatively coupled to the stimulation lead. The pulse generator is configured to generate a waveform including a burst that includes a leading anodic pulse followed by alternating cathodic pulses and anodic pulses, each cathodic pulse in the burst having a greater amplitude than the previous cathodic pulse.
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公开(公告)号：US10792502B2
公开(公告)日：2020-10-06
申请号：US15806690
申请日：2017-11-08
Applicant: ADVANCED NEUROMODULATION SYSTEMS, INC.
Inventor： Filippo Agnesi
Abstract: The systems and methods described herein generally relate to adjusting a neurostimulation (NS) therapy based on drug pharmacokinetics of a patient. The systems and methods deliver an NS therapy to a portion of electrodes of a lead positioned proximate to neural tissue of interest, which is associated with a target region. The NS therapy is defined by stimulation parameters. The systems and methods determine a trigger event indicative of a drug being administered to a patient. The drug is configured to affect at least one of the neural tissue of interest or the target region. The systems and methods adjust one or more of the stimulation parameters based on the PS profile.
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