公开(公告)号：US09902830B2

公开(公告)日：2018-02-27

申请号：US15235283

申请日：2016-08-12

Applicant: Alltech, Inc.

Inventor： Alexandros Yiannikouris ,  Thirupathi R. Yerramreddy ,  Joshua J. Martinez ,  Jeffrey R. Withers

IPC: C08J9/26 ,  C07D311/78 ,  C07D311/16 ,  B01J20/26 ,  C08F222/10

CPC classification number: C08J9/26 ,  B01J20/268 ,  C07D311/16 ,  C07D311/78 ,  C08F222/1006 ,  C08F2222/1013 ,  C08J2201/0422 ,  C08J2335/02 ,  C08F220/06

Abstract: Molecularly imprinted polymers (MIPs) are materials exhibiting molecular recognition of a target molecule. MIPs are synthesized in the presence of an aflatoxin template, a mimic to the targeted molecule, used as an imprint that is further washed away with suitable solvent after completion of the polymerization process, leaving a cavity in the polymer of the same stereochemistry, functionality and morphology to the template. When the MIP encounters an aflatoxin, the molecule is bound in the cavity with a receptor-like affinity.

公开(公告)号：US09672331B2

公开(公告)日：2017-06-06

申请号：US14109926

申请日：2013-12-17

Applicant: Alltech, Inc.

Inventor： Kyle McKinney ,  Allyson Lovell ,  Benjamin Henry ,  Patrick Becker ,  Rebecca A. Timmons

IPC: G01N33/48 ,  G01N33/50 ,  G06F19/00 ,  G01N21/359 ,  A23K10/14 ,  A23K50/75 ,  A23K50/30 ,  G01N21/68

CPC classification number: G06F19/704 ,  A23K10/14 ,  A23K50/30 ,  A23K50/75 ,  G01N21/359 ,  G01N21/68 ,  G01N2201/129 ,  G06F19/00 ,  G06F19/703 ,  G06F19/707 ,  G16H50/50

Abstract: The present application provides systems and methods for analyzing animal feeds and for adjusting animal feeds to improve the digestibility of animal feed components. Digestibility of animal feed can be determined by performing in vitro digestion of the feed and analyzing concentrations of residual components in the digested feed by NIR spectroscopy. Animal feed compositions can be adjusted to improve digestibility of components in the feed. The systems and methods of the present application can be used to determine the effect of an additive on the digestibility of feed.

公开(公告)号：US20160347923A1

公开(公告)日：2016-12-01

申请号：US15235283

申请日：2016-08-12

Applicant: Alltech, Inc.

Inventor： Alexandros Yiannikouris ,  Thirupathi R. Yerramreddy ,  Joshua J. Martinez ,  Jeffrey R. Withers

IPC: C08J9/26 ,  B01J20/26 ,  C08F222/10

CPC classification number: C08J9/26 ,  B01J20/268 ,  C07D311/16 ,  C07D311/78 ,  C08F222/1006 ,  C08F2222/1013 ,  C08J2201/0422 ,  C08J2335/02 ,  C08F220/06

Abstract: Molecularly imprinted polymers (MIPs) are materials exhibiting molecular recognition of a target molecule. MIPs are synthesized in the presence of an aflatoxin template, a mimic to the targeted molecule, used as an imprint that is further washed away with suitable solvent after completion of the polymerization process, leaving a cavity in the polymer of the same stereochemistry, functionality and morphology to the template. When the MIP encounters an aflatoxin, the molecule is bound in the cavity with a receptor-like affinity.

Abstract translation: 分子印迹聚合物（MIP）是表现出目标分子的分子识别的材料。 在黄曲霉毒素模板的存在下合成MIP，模拟靶向分子，用作印记，在聚合过程完成后，用合适的溶剂进一步洗去，留下在相同立体化学，官能度的聚合物中的空腔， 形态到模板。 当MIP遇到黄曲霉毒素时，分子以类似受体的亲和力结合在腔中。