Apparatus and method for detecting array substrate
    21.
    发明授权
    Apparatus and method for detecting array substrate 有权
    阵列基板检测装置及方法

    公开(公告)号:US08451445B2

    公开(公告)日:2013-05-28

    申请号:US12907416

    申请日:2010-10-19

    CPC classification number: G09G3/006 G02F2001/136254 G09G3/3611

    Abstract: An apparatus for detecting an array substrate comprises: a transparent carrier for supporting an array substrate to be detected thereon; a light source disposed on one side of the transparent carrier; and a modulator disposed on the other side in parallel with the transparent carrier. The modulator comprises a liquid crystal layer and two transparent substrate layers disposed on both sides of the liquid crystal layer, and one transparent substrate layer away from the transparent carrier is a first transparent conductive substrate layer, and a second polarizer is disposed thereon. A first polarizer is disposed between the light source and the transparent carrier, so that the light emitted from the light source is transmitted through the first polarizer to the transparent carrier. A light receiver receives the light emitted from the light source and then transmitted through the transparent carrier, the array substrate and the modulator.

    Abstract translation: 一种用于检测阵列基板的装置,包括:用于支撑待检测阵列基板的透明载体; 设置在透明载体的一侧的光源; 以及与透明载体平行设置在另一侧的调制器。 调制器包括液晶层和设置在液晶层两侧的两个透明基板层,离开透明载体的一个透明基板层是第一透明导电基板层,并且第二偏光片设置在其上。 第一偏振器设置在光源和透明载体之间,使得从光源发射的光通过第一偏振器透射到透明载体。 光接收器接收从光源发射的光,然后透过透明载体,阵列基片和调制器。

    DETERMINING VARIANTS IN GENOME OF A HETEROGENEOUS SAMPLE
    22.
    发明申请
    DETERMINING VARIANTS IN GENOME OF A HETEROGENEOUS SAMPLE 审中-公开
    确定异构样品基因组中的变量

    公开(公告)号:US20130110407A1

    公开(公告)日:2013-05-02

    申请号:US13621716

    申请日:2012-09-17

    CPC classification number: G16B40/00 G16B30/00

    Abstract: After DNA fragments are sequenced and mapped to a reference, various hypotheses for the sequences in a variant region can be scored to find which sequence hypotheses are more likely. A hypothesis can include a specific variable fraction for the plurality of alleles that comprise the sequence hypothesis in the region. A likelihood of each hypothesis can be determined using a probability that accounts for the fraction of the alleles specified in the respective sequence hypothesis. Thus, other hypotheses besides standard homozygous and equal heterozygous (i.e., one chromosome with A and one with B in a cell) can be explored by explicitly including the variable fractions of the alleles as a parameter in the optimization. Also, a variant score can be determined for a variant relative to a reference. The variant score can be used to determine a variant calibrated score indicating a likelihood that the variant call is correct.

    Abstract translation: 对DNA片段进行测序并映射到参考文献后,可以对变体区域中的序列进行各种假设,以确定哪些序列假设更有可能。 假设可以包括在该区域中构成序列假设的多个等位基因的特定可变部分。 每个假设的可能性可以使用考虑各个序列假设中规定的等位基因部分的概率来确定。 因此,除了标准纯合和等同杂合(即,具有A和一个在细胞中具有B的一个染色体)之外的其他假设可以通过在优化中明确地包括等位基因的可变部分作为参数来探索。 此外,可以针对相对于参考的变体确定变体得分。 变体得分可用于确定变体校准分数,指示变体调用正确的可能性。

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