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公开(公告)号:US20140287077A1
公开(公告)日:2014-09-25
申请号:US14295022
申请日:2014-06-03
Applicant: AqueSys, Inc.
Inventor: Laszlo O. Romoda , Brian Hamstrom , Partha Chandrakant , Christopher Horvath
IPC: A61F9/007
CPC classification number: A61F9/00781 , A61F9/0017 , A61F2240/001 , B05C3/12 , C23C2/00
Abstract: An intraocular shunt can be manufactured using a system that includes a liquid bath and a wire, which is moved through the bath. When moved through the bath, the wire is coated with a material, such as gelatin. For example, the liquid bath can have a top layer, including water, and a bottom layer, including gelatin. The coated wire passes through an aperture formed in a plate component of the system. The gelatin can be dried on the wire in a humidity-controlled space, thereby forming the shunt.
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公开(公告)号:US11612517B2
公开(公告)日:2023-03-28
申请号:US16679114
申请日:2019-11-08
Applicant: AqueSys, Inc.
Inventor: Christopher Horvath , Laszlo O. Romoda
Abstract: An intraocular shunt can be placed into the eye in an ab externo approach. A clinician may determine an entry area below a corneal limbus of an eye and a target outflow region. Thereafter, the clinician can insert a hollow shaft into the eye at the entry area toward an anterior chamber of the eye, the shaft carrying an intraocular shunt therein. The clinician can position an inflow end of the shunt within the anterior chamber of the eye and, while maintaining the shunt inflow end in the anterior chamber, can remove the shaft from the eye to release the shunt. Finally, the clinician can repositioning an outflow end of the shunt within the target outflow region and verify placement of the outflow end of the shunt within the target outflow region.
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公开(公告)号:US11298264B2
公开(公告)日:2022-04-12
申请号:US16509458
申请日:2019-07-11
Applicant: AqueSys, Inc.
Inventor: Christopher Horvath , Laszlo O. Romoda , Richard A. Lewis
IPC: A61F9/007
Abstract: Glaucoma can be treated by implanting an intraocular shunt in the eye. The implantation can be performed by first determining an entry area below a corneal limbus of an eye. Thereafter, the intraocular shunt can be inserted into eye tissue through the entry area such that an inflow end of the shunt is positioned in the anterior chamber of the eye and an outflow end of the shunt is positioned between layers of Tenon's capsule.
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公开(公告)号:US10940040B2
公开(公告)日:2021-03-09
申请号:US15882984
申请日:2018-01-29
Applicant: AqueSys, Inc.
Inventor: Christopher Horvath , Laszlo O. Romoda
Abstract: Methods are provided for using an intraocular shunt deployment device to deploy an intraocular shunt from the device and into an eye.
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公开(公告)号:US10667947B2
公开(公告)日:2020-06-02
申请号:US15613018
申请日:2017-06-02
Applicant: AqueSys, Inc.
Inventor: Christopher Horvath , Laszlo O. Romoda
Abstract: An ab externo method of placing an intraocular implant into an eye can include advancing a needle, in which the implant is disposed, into the eye through conjunctiva and sclera of the eye. The implant can include a drug deliverable to the eye. The implant can thereafter be released to be anchored in the eye and elute the drug to the eye.
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公开(公告)号:US10653555B2
公开(公告)日:2020-05-19
申请号:US15451274
申请日:2017-03-06
Applicant: AqueSys, Inc.
Inventor: Christopher Horvath , Laszlo O. Romoda , Iqbal K. Ahmed , Brian Scott Hamstrom , Wesley Anne Jung , Vanessa I. Vera , Ronald D. Bache
Abstract: An inserter for treating glaucoma can comprise a housing, a needle, a plunger, a slider component, and a drive component. The drive component is disposed within a cavity of the housing and rotatable within the cavity to result in movement along a longitudinal axis of the inserter to the needle and the plunger upon rotation of the drive component. The slider component is coupled to the housing and slidable along an elongate groove of the drive component such that movement of the slider component along the axis rotates the drive component within the housing.
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公开(公告)号:US10314743B2
公开(公告)日:2019-06-11
申请号:US15454945
申请日:2017-03-09
Applicant: AqueSys, Inc.
Inventor: Laszlo O. Romoda , Brian Hamstrom , Partha Chandrakant , Christopher Horvath
Abstract: An intraocular shunt can be manufactured using a system that includes a liquid bath and a wire, which is moved through the bath. The wire can be moved through a first liquid bath to produce a first tubular layer of drug-infused gelatin. Further, the wire can be moved through a second liquid bath to produce a second tubular layer of drug-free gelatin. The first and second tubular layers can be dried on the wire in a humidity-controlled space, thereby manufacturing a drug-loaded gelatin shunt.
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公开(公告)号:US09980854B2
公开(公告)日:2018-05-29
申请号:US15151393
申请日:2016-05-10
Applicant: AqueSys, Inc.
Inventor: Christopher Horvath , Laszlo O. Romoda , Richard A. Lewis
CPC classification number: A61F9/00781 , A61B17/3417 , A61B17/3468 , A61B2017/3454 , A61F9/007 , A61F9/00736 , A61F2009/00891 , A61M27/002
Abstract: An intraocular shunt can be placed into a human eye using a hollow shaft having a distal tip with a bevel. The hollow shaft can be advanced through the anterior chamber while the hollow shaft holds the intraocular shunt. The distal tip can penetrate the sclera until the bevel is positioned distal to a superficial wall of the sclera. The shunt can be advanced at least partially from the hollow shaft into a drainage space of lower pressure than the anterior chamber. The hollow shaft can be withdrawn from the eye, leaving the shunt extending from the anterior chamber completely through the sclera to the drainage space.
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公开(公告)号:US09877866B2
公开(公告)日:2018-01-30
申请号:US14843887
申请日:2015-09-02
Applicant: AqueSys, Inc.
Inventor: Christopher Horvath , Laszlo O. Romoda
CPC classification number: A61F9/00781
Abstract: Methods are provided for using an intraocular shunt deployment device to deploy an intraocular shunt from the device and into an eye.
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公开(公告)号:US09592154B2
公开(公告)日:2017-03-14
申请号:US14834158
申请日:2015-08-24
Applicant: AqueSys, Inc.
Inventor: Laszlo O. Romoda , Brian Hamstrom , Partha Chandrakant , Christopher Horvath
CPC classification number: A61F9/00781 , A61F9/0017 , A61F2240/001 , B05C3/12 , C23C2/00
Abstract: An intraocular shunt can be manufactured using a system that includes a liquid bath and a wire, which is moved through the bath. When moved through the bath, the wire is coated with a material, such as gelatin. For example, the liquid bath can have a top layer, including water, and a bottom layer, including gelatin. The coated wire passes through an aperture formed in a plate component of the system. The gelatin can be dried on the wire in a humidity-controlled space, thereby forming the shunt.
Abstract translation: 可以使用包括液浴和电线的系统来制造眼内分流器,该系统通过浴液移动。 当通过浴槽移动时,电线用诸如明胶的材料涂覆。 例如,液体浴可以具有包括水在内的顶层和包括明胶在内的底层。 涂覆的线穿过形成在系统的板组件中的孔。 明胶可以在湿度受控的空间中在线材上干燥,从而形成分流器。
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