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公开(公告)号：US11938059B2
公开(公告)日：2024-03-26
申请号：US16854908
申请日：2020-04-22
申请人： AqueSys, Inc.
发明人： Christopher Horvath , Laszlo O. Romoda , Iqbal K. Ahmed , Brian Scott Hamstrom , Wesley Anne Jung , Vanessa I. Vera , Ronald D. Bache
CPC分类号： A61F9/00781 , A61B90/02 , A61F9/0008 , A61F9/0017 , A61M5/3286 , A61M27/002 , A61M2210/0612
摘要： An inserter for treating glaucoma can comprise a housing, a needle, a plunger, a slider component, and a drive component. The drive component is disposed within a cavity of the housing and rotatable within the cavity to result in movement along a longitudinal axis of the inserter to the needle and the plunger upon rotation of the drive component. The slider component is coupled to the housing and slidable along an elongate groove of the drive component such that movement of the slider component along the axis rotates the drive component within the housing.
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公开(公告)号：US10470927B2
公开(公告)日：2019-11-12
申请号：US15172090
申请日：2016-06-02
申请人： AqueSys, Inc.
摘要： Placing an intraocular shunt ab externo into an eye can include inserting the shunt into the eye and either before and/or after insertion, ballooning a target outflow region of the eye to permit an outflow end of the shunt to be enveloped within the ballooned target outflow region. An injector docking device can optionally be used to guide insertion of the needle and shunt into the eye.
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公开(公告)号：US10195078B2
公开(公告)日：2019-02-05
申请号：US15156168
申请日：2016-05-16
申请人： AqueSys, Inc.
发明人： Christopher Horvath , Laszlo O. Romoda , Brian Hamstrom , Ronald D. Bache , Guenther Grabner , Herbert A. Reitsamer
摘要： Methods and devices for adjusting or configuring the flow rate of an intraocular shunt are provided whereby hypotony can be avoided by increasing the flow rate through the device. In some embodiments, the device is a shunt that can have a first flow that can be modified to a second flow by modifying the shunt, such as by cutting the shunt. Additionally, one or more dissolvable portions can be present to provide an initial flow restriction and subsequent increase in flow over time.
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公开(公告)号：US10080682B2
公开(公告)日：2018-09-25
申请号：US15158368
申请日：2016-05-18
申请人： AqueSys, Inc.
CPC分类号： A61F9/00781 , A61F9/0017 , A61F9/007 , A61L27/222 , A61L27/34 , A61L27/54 , A61L2430/16 , A61M37/0069
摘要： Glaucoma can be treated by implanting an intraocular shunt into an eye. The eye has an anterior chamber and sclera. A shunt can be placed into the eye to establish fluid communication from the anterior chamber of the eye through the sclera, and a pharmaceutical or biological agent can be administered to the eye.
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公开(公告)号：US09883969B2
公开(公告)日：2018-02-06
申请号：US15005954
申请日：2016-01-25
申请人： AqueSys, Inc.
CPC分类号： A61F9/00781 , A61F2/82 , A61F9/0017 , A61F9/007 , A61F9/00736 , A61F9/00763 , A61F2009/00861 , A61F2009/00865 , A61F2009/00872 , A61M27/002 , A61M2210/0612
摘要： Glaucoma can be treated by implanting an intraocular shunt into an eye. The eye has an anterior chamber and sclera. A shunt can be placed into the eye to establish fluid communication from the anterior chamber of the eye through the sclera.
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公开(公告)号：US09192516B2
公开(公告)日：2015-11-24
申请号：US14191340
申请日：2014-02-26
申请人： AqueSys, Inc.
CPC分类号： A61F9/00781
摘要： Methods are provided for using an intraocular shunt deployment device to deploy an intraocular shunt from the device and into an eye.
摘要翻译： 提供了使用眼内分路部署装置从装置部署眼内分流并进入眼睛的方法。
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公开(公告)号：US09095413B2
公开(公告)日：2015-08-04
申请号：US14295022
申请日：2014-06-03
申请人： AqueSys, Inc.
CPC分类号： A61F9/00781 , A61F9/0017 , A61F2240/001 , B05C3/12 , C23C2/00
摘要： An intraocular shunt can be manufactured using a system that includes a liquid bath and a wire, which is moved through the bath. When moved through the bath, the wire is coated with a material, such as gelatin. For example, the liquid bath can have a top layer, including water, and a bottom layer, including gelatin. The coated wire passes through an aperture formed in a plate component of the system. The gelatin can be dried on the wire in a humidity-controlled space, thereby forming the shunt.
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公开(公告)号：US09017276B2
公开(公告)日：2015-04-28
申请号：US13952543
申请日：2013-07-26
申请人： AqueSys, Inc.
CPC分类号： A61F9/00781 , A61B17/3417 , A61B17/3468 , A61B2017/3454 , A61F9/007 , A61F9/00736 , A61F2009/00891 , A61M27/002
摘要： The present invention generally relates to intraocular shunts, and in particular, to intraocular shunts configured to form a drainage pathway between the anterior chamber and the intra-Tenon's space.
摘要翻译： 本发明一般涉及眼内分流术，尤其涉及眼内分流装置，其被配置成在前房和内腔内部之间形成排水通路。
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公开(公告)号：US20140243730A1
公开(公告)日：2014-08-28
申请号：US13778873
申请日：2013-02-27
申请人： AqueSys, Inc.
发明人： Christopher Horvath
IPC分类号： A61F9/007
CPC分类号： A61F9/00781 , A61F9/00 , A61F9/007
摘要： The present invention generally relates to devices and methods of implanting an intraocular shunt into an eye. In certain aspects, methods of the invention involve creating an opening in the sclera, and positioning a shunt in the anterior chamber of the eye such that the shunt terminates via the opening in the intra-scleral space, thereby facilitating fluid flow through both the opening and the intra-scleral space.
摘要翻译： 本发明一般涉及将眼内分流植入眼睛的装置和方法。 在某些方面，本发明的方法涉及在巩膜中产生开口，并且将分流器定位在眼睛的前房中，使得分路通过巩膜内空间中的开口终止，从而便于流体流过两个开口 和巩膜内空间。
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公开(公告)号：US20240197531A1
公开(公告)日：2024-06-20
申请号：US18494154
申请日：2023-10-25
申请人： AqueSys, Inc.
CPC分类号： A61F9/00781 , A61B17/3415 , A61B17/3468 , A61B17/3417 , A61F9/0008 , A61F9/0017 , A61F9/007 , A61M27/002
摘要： Glaucoma can be treated by implanting an intraocular shunt into the eye. Such procedures can employ various deployment devices, shunts, and implantation techniques. A method of treating glaucoma can be performed by a clinician, in which a hollow needle is inserted into an eye through the sclera. The hollow needle can carry an intraocular shunt. Once inserted and properly positioned, the clinician can release the shunt from the needle such that the shunt conducts fluid away from the anterior chamber of the eye.
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