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公开(公告)号：US06613045B1
公开(公告)日：2003-09-02
申请号：US09495667
申请日：2000-02-01
IPC分类号： A61B1804
CPC分类号： A61B18/08 , A61B18/1492 , A61B2017/22051 , A61B2017/22097 , A61B2018/00083 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00285 , A61B2018/00404 , A61B2018/00488 , A61B2018/00755 , A61B2018/00797 , A61B2018/00875 , A61B2018/1253 , A61B2018/126 , A61B2018/1465 , A61B2018/1497
摘要： A catheter delivers an electrode within a vein for a minimally invasive treatment of varicose veins and venous insufficiency using RF energy. The catheter is introduced into a patient and positioned within the section of the vein to be treated. The electrode radiates high frequency energy towards the vein, and the surrounding venous tissue becomes heated and begins to shrink. The catheter includes a controllable member for limiting the amount of shrinkage of the vein to the diameter of the member. The electrode remains active until there has been sufficient shrinkage of the vein. The extent of shrinkage of the vein may be detected by fluoroscopy. After treating one section of the vein, the catheter and the electrode can be repositioned intraluminally within the vein to treat different sections of the vein until all desired venous sections and valves are repaired and rendered functionally competent.
摘要翻译： 导管在静脉内输送电极，以便使用RF能量进行静脉曲张和静脉功能不全的微创治疗。 将导管引入患者并定位在待治疗的静脉的部分内。 电极向静脉辐射高频能量，周围的静脉组织变热并开始收缩。 导管包括可控制的构件，用于限制静脉的收缩量与构件的直径。 电极保持活动，直到静脉充分收缩。 静脉收缩的程度可以通过荧光透视法检测。 在治疗静脉的一部分后，导管和电极可以在静脉内腔内重新定位，以处理静脉的不同部分，直到所有期望的静脉部分和瓣膜被修复并且具有功能上的能力。
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22.发明授权Expandable catheter having improved electrode design, and method for applying energy 失效具有改进的电极设计的可扩展导管和施加能量的方法公开(公告)号：US06638273B1
公开(公告)日：2003-10-28
申请号：US09724248
申请日：2000-11-27
申请人： Brian E. Farley , Grace Y. Schulz , Dawn A. Henderson , Mark P. Parker , Arthur W. Zikorus , Gary H. Miller , Jay S. Daulton , Douglas Portnow
发明人： Brian E. Farley , Grace Y. Schulz , Dawn A. Henderson , Mark P. Parker , Arthur W. Zikorus , Gary H. Miller , Jay S. Daulton , Douglas Portnow
IPC分类号： A61B1804
CPC分类号： A61B18/1492 , A61B17/00008 , A61B2017/22051 , A61B2017/22097 , A61B2018/00011 , A61B2018/00029 , A61B2018/00083 , A61B2018/00154 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00285 , A61B2018/00404 , A61B2018/00488 , A61B2018/00702 , A61B2018/00744 , A61B2018/00755 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00875 , A61B2018/1253 , A61B2018/126 , A61B2018/1465 , A61B2018/1497
摘要： A catheter having expandable electrodes for applying energy to a hollow anatomical structure such as a vein. When used on a vein, the catheter is useful for a minimally invasive treatment of venous insufficiency. The catheter includes conductive end rings to which the electrodes are attached, for mechanically connecting and electrically tying electrodes together to provide for a single wire electrical connection points, for transmitting energy while more evenly spacing the electrodes. Expandable arms are formed of electrically conductive material and insulated along their length except for an intermediate section that functions as the electrode. The arms are tapered to allow more room for wiring and to reduce the possibility of shorting between the ends of the arms. The catheter further includes thermocouples in the electrodes for measuring temperatures on the outer surface of the electrode. Slots are formed in the arms for mounting the thermocouples. The temperature at the hollow anatomical structure is monitored and if a rapid, large temperature decrease of short duration is noted, the power is maintained constant as a fluid flush has been detected.
摘要翻译： 具有用于向诸如静脉的中空解剖结构施加能量的可扩张电极的导管。 当静脉使用时，导管可用于静脉功能不全的微创治疗。 导管包括导电端环，电极附接到该导电端环，用于将电极机械连接并电连接在一起，以提供单线电连接点，用于在更均匀地间隔电极的同时发射能量。 可扩展臂由导电材料形成并且沿其长度绝缘，除了用作电极的中间部分之外。 臂是锥形的，以允许更多的布线空间并且减少在臂的端部之间短路的可能性。 该导管还包括用于测量电极外表面上的温度的电极中的热电偶。 插槽形成在用于安装热电偶的臂中。 监测中空解剖结构的温度，如果注意到持续时间短的快速，大的温度降低，则检测到流体冲洗时，功率保持恒定。
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公开(公告)号：US6036687A
公开(公告)日：2000-03-14
申请号：US610911
申请日：1996-03-05
CPC分类号： A61B18/08 , A61B18/1492 , A61B2017/22051 , A61B2017/22097 , A61B2018/00083 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00285 , A61B2018/00404 , A61B2018/00488 , A61B2018/00755 , A61B2018/00797 , A61B2018/00875 , A61B2018/1253 , A61B2018/126 , A61B2018/1465 , A61B2018/1497
摘要： A catheter delivers an electrode within a vein for a minimally invasive treatment of varicose veins and venous insufficiency using RF energy. The catheter is introduced into a patient and positioned within the section of the vein to be treated. The electrode radiates high frequency energy towards the vein, and the surrounding venous tissue becomes heated and begins to shrink. The catheter includes a controllable member for limiting the amount of shrinkage of the vein to the diameter of the member. The electrode remains active until there has been sufficient shrinkage of the vein. The extent of shrinkage of the vein may be detected by fluoroscopy. After treating one section of the vein, the catheter and the electrode can be repositioned intraluminally within the vein to treat different sections of the vein until all desired venous sections and valves are repaired and rendered functionally competent.
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公开(公告)号：US06361496B1
公开(公告)日：2002-03-26
申请号：US09322326
申请日：1999-05-28
IPC分类号： A61B800
CPC分类号： A61B17/135 , A61B8/04 , A61B17/1325
摘要： A pressure tourniquet having a window transparent to ultrasound is wrapped around a leg or another anatomical structure containing veins. An ultrasound transducer is placed in contact with the window of the tourniquet. The window is adjacent the anatomical structure and the transducer probes a dilated vein with ultrasound. The transducer can measure the size of the vein and detect reflux. A pneumatic bladder on the tourniquet is inflated to apply pressure to the anatomical structure so that the vein is compressed by the tissue of the surrounding anatomical structure. As pressure from the tourniquet reduces the diameter of the vein, competency of the vein valve can be temporarily restored to indicate the proper reduced diameter required to restore venous function. An electrode catheter is introduced into the vein to apply energy for durably molding the vein to the reduced diameter.
摘要翻译： 具有对超声波透明的窗口的压力止血带缠绕在包含静脉的腿部或另外的解剖结构上。 将超声换能器放置成与止血带的窗口接触。 窗口与解剖结构相邻，传感器用超声波探测扩张的静脉。 传感器可以测量静脉的大小并检测回流。 止血带上的充气气囊被充气以向解剖结构施加压力，使得静脉被周围解剖结构的组织压缩。 由于止血带的压力降低了静脉的直径，静脉瓣的能力可以暂时恢复，以指示恢复静脉功能所需的适当减小的直径。 将电极导管引入静脉以施加能量以持久地模制静脉直径减小。
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公开(公告)号：US6152899A
公开(公告)日：2000-11-28
申请号：US895850
申请日：1997-07-17
申请人： Brian E. Farley , Grace Y. Schulz , Dawn A. Henderson , Mark P. Parker , Arthur W. Zikorus , Gary H. Miller , Jay S. Daulton , Douglas Portnow
发明人： Brian E. Farley , Grace Y. Schulz , Dawn A. Henderson , Mark P. Parker , Arthur W. Zikorus , Gary H. Miller , Jay S. Daulton , Douglas Portnow
CPC分类号： A61B18/1492 , A61B17/00008 , A61B2017/22051 , A61B2017/22097 , A61B2018/00011 , A61B2018/00029 , A61B2018/00083 , A61B2018/00154 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00285 , A61B2018/00404 , A61B2018/00488 , A61B2018/00702 , A61B2018/00744 , A61B2018/00755 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00875 , A61B2018/1253 , A61B2018/126 , A61B2018/1465 , A61B2018/1497
摘要： A catheter having expandable electrodes for applying energy to a hollow anatomical structure such as a vein. When used on a vein, the catheter is useful for a minimally invasive treatment of venous insufficiency. The catheter includes conductive end rings to which the electrodes are attached, for mechanically connecting and electrically tying electrodes together to provide for a single wire electrical connection points, for transmitting energy while more evenly spacing the electrodes. Expandable arms are formed of electrically conductive material and insulated along their length except for an intermediate section that functions as the electrode. The arms are tapered to allow more room for wiring and to reduce the possibility of shorting between the ends of the arms. The catheter further includes thermocouples in the electrodes for measuring temperatures on the outer surface of the electrode. Slots are formed in the arms for mounting the thermocouples. The temperature at the hollow anatomical structure is monitored and if a rapid, large temperature decrease of short duration is noted, the power is maintained constant as a fluid flush has been detected.
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公开(公告)号：US6165172A
公开(公告)日：2000-12-26
申请号：US958766
申请日：1997-10-26
申请人： Brian E. Farley , Dawn A. Henderson , Christopher S. Jones , Mark P. Parker , Joseph M. Tartaglia
发明人： Brian E. Farley , Dawn A. Henderson , Christopher S. Jones , Mark P. Parker , Joseph M. Tartaglia
CPC分类号： A61B18/1492 , A61B2017/00084 , A61B2017/22038 , A61B2017/22051 , A61B2018/00214 , A61B2018/0022 , A61B2018/00404 , A61B2018/124 , A61B2018/1253 , A61B2018/126 , A61B2018/1475 , A61B2090/3782 , A61B2218/002
摘要： A catheter includes a plurality of primary leads to deliver energy for ligating a hollow anatomical structure. Each of the primary leads includes an electrode located at the working end of the catheter. Separation is maintained between the primary leads such that each primary lead can individually receive power of selected polarity. The primary leads are constructed to expand outwardly to place the electrodes into apposition with a hollow anatomical structure. High frequency energy can be applied from the leads to create a heating effect in the surrounding tissue of the anatomical structure. The diameter of the hollow anatomical structure is reduced by the heating effect, and the electrodes of the primary leads are moved closer to one another. Where the hollow anatomical structure is a vein, energy is applied until the diameter of the vein is reduced to the point where the vein is occluded. In one embodiment, a balloon is inflated to occlude the structure before the application of energy. Where the structure is a vein, the inflated balloon obstructs blood flow and facilitates the infusion of saline, medication, or a high-impedance fluid to the vein in order to reduce the occurrence of coagulation and to improve the heating of the vein by the catheter. The catheter can include a lumen to accommodate a guide wire or to allow fluid delivery.
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公开(公告)号：US07041098B2
公开(公告)日：2006-05-09
申请号：US10162057
申请日：2002-06-03
申请人： Brian E. Farley , Dawn A. Henderson , Christopher S. Jones , Mark P. Parker , Joseph M. Tartaglia
发明人： Brian E. Farley , Dawn A. Henderson , Christopher S. Jones , Mark P. Parker , Joseph M. Tartaglia
IPC分类号： A61B18/18
CPC分类号： A61B18/1492 , A61B2017/22038 , A61B2017/22051 , A61B2017/22067 , A61B2018/00214 , A61B2018/0022 , A61B2018/00404 , A61B2018/00488 , A61B2018/00589 , A61B2018/00898 , A61B2018/124 , A61B2018/1253 , A61B2018/126 , A61B2090/3782 , A61B2218/002
摘要： A catheter includes a plurality of primary leads to deliver energy for ligating a hollow anatomical structure. Each of the primary leads includes an electrode located at the working end of the catheter. Separation is maintained between the primary leads such that each primary lead can individually receive power of selected polarity. The primary leads are constructed to expand outwardly to place the electrodes into apposition with a hollow anatomical structure. High frequency energy can be applied from the leads to create a heating effect in the surrounding tissue of the anatomical structure. The diameter of the hollow anatomical structure is reduced by the heating effect, and the electrodes of the primary leads are moved closer to one another. Where the hollow anatomical structure is a vein, energy is applied until the diameter of the vein is reduced to the point where the vein is occluded. In one embodiment, a balloon is inflated to occlude the structure before the application of energy. Where the structure is a vein, the inflated balloon obstructs blood flow and facilitates the infusion of saline, medication, or a high-impedance fluid to the vein in order to reduce the occurrence of coagulation and to improve the heating of the vein by the catheter. The catheter can include a lumen to accommodate a guide wire or to allow fluid delivery.
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公开(公告)号：US06398780B1
公开(公告)日：2002-06-04
申请号：US09497099
申请日：2000-02-03
申请人： Brian E. Farley , Dawn A. Henderson , Christopher S. Jones , Mark P. Parker , Joseph M. Tartaglia
发明人： Brian E. Farley , Dawn A. Henderson , Christopher S. Jones , Mark P. Parker , Joseph M. Tartaglia
IPC分类号： A61B1739
CPC分类号： A61B18/1492 , A61B2017/22038 , A61B2017/22051 , A61B2017/22067 , A61B2018/00214 , A61B2018/0022 , A61B2018/00404 , A61B2018/00488 , A61B2018/00589 , A61B2018/00898 , A61B2018/124 , A61B2018/1253 , A61B2018/126 , A61B2090/3782 , A61B2218/002
摘要： A catheter includes a plurality of primary leads to deliver energy for ligating a hollow anatomical structure. Each of the primary leads includes an electrode located at the working end of the catheter. Separation is maintained between the primary leads such that each primary lead can individually receive power of selected polarity. The primary leads are constructed to expand outwardly to place the electrodes into apposition with a hollow anatomical structure. High frequency energy can be applied from the leads to create a heating effect in the surrounding tissue of the anatomical structure. The diameter of the hollow anatomical structure is reduced by the heating effect, and the electrodes of the primary leads are moved closer to one another. Where the hollow anatomical structure is a vein, energy is applied until the diameter of the vein is reduced to the point where the vein is occluded. In one embodiment, a balloon is inflated to occlude the structure before the application of energy. Where the structure is a vein, the inflated balloon obstructs blood flow and facilitates the infusion of saline, medication, or a high-impedance fluid to the vein in order to reduce the occurrence of coagulation and to improve the heating of the vein by the catheter. The catheter can include a lumen to accommodate a guide wire or to allow fluid delivery.
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公开(公告)号：US06689126B1
公开(公告)日：2004-02-10
申请号：US09497278
申请日：2000-02-03
申请人： Brian E. Farley , Dawn A. Henderson , Christopher S. Jones , Mark P. Parker , Joseph M. Tartaglia
发明人： Brian E. Farley , Dawn A. Henderson , Christopher S. Jones , Mark P. Parker , Joseph M. Tartaglia
IPC分类号： A61B1804
CPC分类号： A61B18/1492 , A61B2017/22038 , A61B2017/22051 , A61B2017/22067 , A61B2018/00214 , A61B2018/0022 , A61B2018/00404 , A61B2018/00488 , A61B2018/00589 , A61B2018/00898 , A61B2018/124 , A61B2018/1253 , A61B2018/126 , A61B2090/3782 , A61B2218/002
摘要： A catheter includes a plurality of primary leads to deliver energy for ligating a hollow anatomical structure. Each of the primary leads includes an electrode located at the working end of the catheter. Separation is maintained between the primary leads such that each primary lead can individually receive power of selected polarity. The primary leads are constructed to expand outwardly to place the electrodes into apposition with a hollow anatomical structure. High frequency energy can be applied from the leads to create a heating effect in the surrounding tissue of the anatomical structure. The diameter of the hollow anatomical structure is reduced by the heating effect, and the electrodes of the primary leads are moved closer to one another. Where the hollow anatomical structure is a vein, energy is applied until the diameter of the vein is reduced to the point where the vein is occluded. In one embodiment, a balloon is inflated to occlude the structure before the application of energy. Where the structure is a vein, the inflated balloon obstructs blood flow and facilitates the infusion of saline, medication, or a high-impedance fluid to the vein in order to reduce the occurrence of coagulation and to improve the heating of the vein by the catheter. The catheter can include a lumen to accommodate a guide wire or to allow fluid delivery.
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公开(公告)号：US07976536B2
公开(公告)日：2011-07-12
申请号：US11280778
申请日：2005-11-16
IPC分类号： A61B18/18
CPC分类号： A61B18/1492 , A61B17/00008 , A61B2017/22051 , A61B2017/22097 , A61B2018/00011 , A61B2018/00029 , A61B2018/00083 , A61B2018/00154 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00285 , A61B2018/00404 , A61B2018/00488 , A61B2018/00702 , A61B2018/00744 , A61B2018/00755 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00875 , A61B2018/1253 , A61B2018/126 , A61B2018/1465 , A61B2018/1497
摘要： A catheter introduces electrodes in a vein for a minimally invasive treatment of venous insufficiency by the application of energy to cause selective heating of the vein. The catheter is positioned within the vein to be treated, and the electrodes on the catheter are moved toward one side of the vein. RF energy is applied in a directional manner from the electrodes at the working end of the catheter to cause localized heating and corresponding shrinkage of the adjacent venous tissue, which may include commissures, leaflets and ostia. Fluoroscopy or ultrasound may be used to detect shrinkage of the vein. After treating one section of the vein, the catheter can be repositioned to place the electrodes to treat different sections of the vein until all desired venous valves are repaired and rendered functionally competent.
摘要翻译： 导管通过施加能量来引起静脉的选择性加热，将电极引入静脉中用于微创治疗静脉功能不全。 将导管定位在待治疗的静脉内，导管上的电极向静脉的一侧移动。 射频能量以定向方式从导管的工作端处的电极施加以引起相邻静脉组织的局部加热和相应的收缩，其可以包括连合，小叶和口。 荧光透视或超声可用于检测静脉的收缩。 在治疗静脉的一部分之后，可以重新定位导管以放置电极来治疗静脉的不同部分，直到所有期望的静脉瓣被修复并且具有功能上的能力。
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