公开(公告)号：US20210137412A1

公开(公告)日：2021-05-13

申请号：US17097421

申请日：2020-11-13

Applicant: California Institute of Technology

Inventor： Saransh Sharma ,  Mikhail Shapiro ,  Azita Emami

IPC: A61B5/07 ,  A61B5/00 ,  A61B5/05

Abstract: A method for in-vivo monitoring of a target internal volume of a mammal that includes: (a) placing the target internal volume proximal to a three-dimensional magnetic field generator; (b) generating first, second, and third magnetic field gradients along respective first, second, and third axes that are mutually orthogonal; (c) measuring first, second, and third magnetic fields with a three-dimensional magnetic sensor disposed in an ingestible capsule, the ingestible capsule disposed in the target internal volume; (d) with a controller in electrical communication with the three-dimensional magnetic sensor, generating a magnetic sensor output signal that encodes a measurement of the first, second, and third magnetic fields; (e) broadcasting the magnetic sensor output signal from an antenna disposed in the ingestible capsule, and (f) receiving the magnetic sensor output signal with a receiver. The received magnetic field data can be used to determine the three-dimensional position of the ingestible capsule.

公开(公告)号：US09915641B2

公开(公告)日：2018-03-13

申请号：US14561114

申请日：2014-12-04

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Mikhail Shapiro ,  Azita Emami ,  Manuel Alejandro Monge Osorio

IPC: G01N33/46 ,  G01N33/483 ,  G01R17/00 ,  G01R33/07 ,  A61B5/00 ,  A61B5/04 ,  A61B5/07 ,  A61B5/05 ,  H04B1/40 ,  G01R33/12

CPC classification number: G01N33/483 ,  A61B5/0522 ,  A61B5/073 ,  G01R33/077 ,  G01R33/1269 ,  G01R33/1284 ,  H04B1/40

Abstract: Methods and apparatuses for sensing biological functions are disclosed. Sensors can be implanted in an organ, such as the brain, and a magnetic field gradient applied to the biological tissue. The field causes the sensors to have different resonant frequencies allowing their spatial localization. The sensors can harvest power from the external coils to be able to retransmit data.