摘要:
The present invention provides a method of screening for compounds which affect the processing of EphA4 by γ-secretase, comprising the following steps: (i) contacting a first biological composition containing γ-secretase or a biologically active fragment thereof with a second biological composition containing EphA4 in the presence and absence of a candidate compound; (ii) measuring the cleavage of the EphA4 in the presence and absence of the candidate compound; (iii) selecting those candidate compounds which affect the cleavage of the EphA4 by γ-secretase; and (iv) identifying the candidate compounds selected in step (iii) as compounds which affect the processing of EphA4 by γ-secretase.
摘要:
A toroidal type continuously variable transmission has an input shaft to which a rotation torque is input, an input side disk and an output side disk that are concentrically and rotatably supported by the input shaft in a state that an inner peripheral surface of the input side disk opposes to an inner peripheral surface of the output side disk, a power roller held between the input side disk and the output side disk and a hydraulic loading device applying predetermined pressing force so that the power roller is pressed between the input and output side disks. Fine grooves are formed on at least a radially inner part of the inner peripheral surface of the input side disk and at least radially outer part of the inner peripheral surface of the output side disk, respectively.
摘要:
A continuously variable transmission apparatus, has: an input shaft; a toroidal-type continuously variable transmission; a first rotation transmission shaft; a first planetary-gear-type transmission; a second planetary-gear-type transmission; a second rotation transmission shaft; an output shaft; a first power transmission mechanism; a second power transmission mechanism; and a switching mechanism, wherein, in a state where the power transmission through the first power transmission mechanism is allowed and the power transmission through the second power transmission mechanism is cut off, in accordance with the control of the transmission ratio of the toroidal-type continuously variable transmission, the output shaft be stopped while leaving the input shaft rotating.
摘要:
A continuously variable transmission apparatus includes a toroidal continuously variable transmission, a planetary gear transmission and a clutch apparatus that connects the toroidal continuously variable transmission and the planetary gear transmission. The clutch apparatus includes: a low speed clutch a high speed clutch and a controller. The controller controls the transmission ratio of the toroidal continuously variable transmission so that rotational speeds of members connected via the clutch apparatus equals with each other, and then disengages the one of the low speed clutch and the high speed clutch after engaging the other, whereby an instance of simultaneously transmitting the power by the two clutches is set during a time period until disconnecting the other clutch after starting to transmit the power by the one clutch.
摘要:
A continuously variable transmission apparatus includes: an input shaft, an output shaft, a toroidal continuously variable transmission, a gear-type differential unit including a plurality of gears, and a controller. The controller calculates a torque actually passing through the toroidal continuously variable transmission to obtain a deviation of the torque from a target value and adjusts a transmission ratio of the toroidal continuously variable transmission to eliminate the deviation. The controller stops the adjustment of the transmission ratio when the torque is not stable.
摘要:
A toroidal-type continuously variable transmission according to the present invention includes an input shaft, an input disk and an output disk, plural power rollers, a power roller bearing, an oil passage, and a mesh filter. The input and output disks are supported mutually concentrically with said input shaft and mutually independently rotatably. The plural power rollers are sandwiched between said input disk and said output disks. The power roller bearing rotatably supports said power rollers. The oil passage for leading lubricating oil to said power roller bearing. The mesh filter is provided in said oil passage. Accordingly, the toroidal-type continuously variable transmission can prevent an occurrence of biting-in of foreign substances at a power roller bearing, to thereby increase the life of the power roller bearing.
摘要:
A power driving device comprises a fluid coupling operated by an engine, a wet-type friction clutch disposed between said fluid coupling and a transmission, and a fluid operation means for circulating the operation fluid through said fluid coupling and for feeding the operation fluid to the wet-type friction clutch. In the pump housing of the fluid operation means, there is disposed a hydraulic pump that works as a source of hydraulic pressure, there are formed passages for communicating said hydraulic pump with said fluid coupling and with said wet-type friction clutch, and there are disposed a relief valve for adjusting the pressure of the operation fluid blown out from the hydraulic pump, a control valve for changing over the passage communicated with the fluid coupling and a control valve for changing over the passage communicated with the wet-type friction clutch.
摘要:
Provided is a method for efficiently producing iron carbide depending on a particle size of an iron-containing material or the progress of reaction. In a fluidized bed reactor 7, a coarse iron ore is fluidized in blocks 8a to 8e, a fine iron ore is fluidized in blocks 9a to 9d, and a flow rate of a reaction gas supplied to the blocks for the fine iron ore is regulated by a flow regulating valve 11.
摘要:
Powdered ore is fed into fluidized bed reactor 1 after preheating by hot blast in preheating furnace 2. Iron oxide particles are recovered from an exhaust gas of the preheating furnace 2 by dust catcher 3, and the iron oxide particles are reduced to iron in reducing furnace 4. The reduced iron particles are added into the flow path of fluidized bed reactor 1 to catalyze the reaction producing iron carbide.
摘要:
This toroidal continuous variable transmission detects a deviation of the spool valve from its neutral position and performs a feedback control to prevent the transmission ratio from converging on other than the target transmission ratio or the speed change sequence from being started again. Further, the toroidal continuous variable transmission performs control so that as the actual transmission ratio approaches the target transmission ratio, the transmission speed decreases in order to prevent an overshoot of the speed change control. When the difference between the actual transmission ratio and the target transmission ratio is smaller than a specified value, the output signals to the solenoid valves are controlled so that the pressure difference between the pilot pressures acting on the ends of the spool valves is proportional to the difference between the actual transmission ratio and the target transmission ratio. When the difference between the actual transmission ratio and the target transmission ratio exceeds the specified value, the target transmission speed is set according to the difference and the output signals to the solenoid valves are controlled so that the pressure difference between the pilot pressures acting on the ends of the spools is proportional to the difference between the actual transmission speed and the target transmission speed.