公开(公告)号：US08649585B2

公开(公告)日：2014-02-11

申请号：US13295416

申请日：2011-11-14

Applicant: Hui Xue ,  Saurabh Shah ,  Christoph Guetter ,  Marie-Pierre Jolly ,  Sven Zuehlsdorff ,  Jens Guehring

Inventor： Hui Xue ,  Saurabh Shah ,  Christoph Guetter ,  Marie-Pierre Jolly ,  Sven Zuehlsdorff ,  Jens Guehring

IPC: G06K9/00

CPC classification number: G06T5/50 ,  G06T5/002 ,  G06T2207/10016 ,  G06T2207/10088 ,  G06T2207/20221 ,  G06T2207/30048

Abstract: A method and system for retrospective image combination for free-breathing magnetic resonance (MR) images is disclose. A free-breathing cardiac MR image acquisition including a plurality of frames is received. A key frame is selected of the plurality of frames. A deformation field for each frame to register each frame with the key frame. A weight is determined for each pixel in each frame based on the deformation field for each frame under a minimum total deformation constraint. A combination image is then generated as a weighted average of the frames using the weight determined for each pixel in each frame.

Abstract translation: 公开了用于自由呼吸磁共振（MR）图像的回顾性图像组合的方法和系统。 接收包括多个帧的自由呼吸心脏MR图像采集。 选择多个帧中的关键帧。 每个帧的变形场用关键帧来记录每个帧。 基于每个帧在最小总变形约束下的变形场，为每个帧中的每个像素确定权重。 然后，使用为每个帧中的每个像素确定的权重，生成组合图像作为帧的加权平均。

公开(公告)号：US20130278259A1

公开(公告)日：2013-10-24

申请号：US13866328

申请日：2013-04-19

Applicant: Andreas Greiser ,  Peter Schmitt ,  Hui Xue

Inventor： Andreas Greiser ,  Peter Schmitt ,  Hui Xue

IPC: G01R33/50

CPC classification number: G01R33/50 ,  G01R33/56 ,  G01R33/56509

Abstract: In a method for a rapid determination of spatially resolved magnetic resonance relaxation parameters in an area of examination, a preparation pulse is radiated into the area of examination. During the relaxation of the longitudinal magnetization, spatially encoded magnetic resonance signals are acquired at a minimum of two different points in time using a fast magnetic resonance sequence. At each inversion time, an image data record is reconstructed from the magnetic resonance signals, which are elastically registered to each other. From the recorded image data records, values of magnetic resonance relaxation parameters are spatially accurately determined.

Abstract translation: 在用于在检查区域中快速确定空间分辨的磁共振松弛参数的方法中，准备脉冲被辐射到检查区域中。 在松弛纵向磁化期间，使用快速磁共振序列在至少两个不同的时间点获取空间编码的磁共振信号。 在每个反转时间，从彼此弹性对准的磁共振信号重建图像数据记录。 从记录的图像数据记录中，磁共振松弛参数的值在空间上被精确地确定。

公开(公告)号：US20120189183A1

公开(公告)日：2012-07-26

申请号：US13237198

申请日：2011-09-20

Applicant: Hui Xue ,  Saurabh Shah ,  Jens Gühring ,  Andreas Greiser ,  Christophe Chefd'hotel ,  Christoph Guetter ,  Marie-Pierre Jolly ,  Sven Zuehlsdorff

Inventor： Hui Xue ,  Saurabh Shah ,  Jens Gühring ,  Andreas Greiser ,  Christophe Chefd'hotel ,  Christoph Guetter ,  Marie-Pierre Jolly ,  Sven Zuehlsdorff

IPC: G06K9/40 ,  G06K9/00

CPC classification number: G06T5/50 ,  G01R33/448 ,  G01R33/56509 ,  G06T7/30 ,  G06T2207/10088 ,  G06T2207/20201 ,  G06T2207/30048

Abstract: A method for performing motion compensation in a series of magnetic resonance (MR) images includes acquiring a set of MR image frames spanning different points along an MR recovery curve. A motion-free synthetic image is generated for each of the acquired MR image frames using prior knowledge pertaining to an MR recovery curve. Each of the acquired MR images is registered to its corresponding generated synthetic images. Motion within each of the acquired MR image is corrected based on its corresponding generated synthetic image that has been registered thereto.

Abstract translation: 用于在一系列磁共振（MR）图像中执行运动补偿的方法包括获取沿着MR恢复曲线横跨不同点的一组MR图像帧。 使用与MR恢复曲线相关的先前知识，为每个所获取的MR图像帧生成无运动合成图像。 所获取的MR图像中的每一个被注册到其对应的生成的合成图像。 基于其对应的生成的已经被注册的合成图像来校正所获取的MR图像的每一个内的运动。

公开(公告)号：US20120177269A1

公开(公告)日：2012-07-12

申请号：US13234694

申请日：2011-09-16

Applicant: Xiaoguang Lu ,  Jens Gühring ,  Hui Xue ,  Marie-Pierre Jolly ,  Christoph Guetter ,  Bogdan Georgescu ,  Sven Zuehlsdorff ,  Arne Littmann

Inventor： Xiaoguang Lu ,  Jens Gühring ,  Hui Xue ,  Marie-Pierre Jolly ,  Christoph Guetter ,  Bogdan Georgescu ,  Sven Zuehlsdorff ,  Arne Littmann

IPC: G06K9/00

CPC classification number: G06K9/4609 ,  G06K2209/051 ,  G06T7/11 ,  G06T7/143 ,  G06T7/194 ,  G06T2207/10088 ,  G06T2207/20164 ,  G06T2207/30048

Abstract: A method including receiving an image sequence, wherein the image sequence includes a plurality of two-dimensional (2D) image frames of an organ arranged in a time sequence; constructing a three-dimensional (3D) volume by stacking a plurality of the 2D image frames in time order; detecting a best bounding box for a target of interest in the 3D volume, wherein the best bounding box is specified by a plurality of parameters including spatial and temporal information contained in the 3D volume; and determining the target of interest from the best bounding box.

Abstract translation: 一种包括接收图像序列的方法，其中所述图像序列包括以时间顺序排列的器官的多个二维（2D）图像帧; 通过以时间顺序堆叠多个2D图像帧来构造三维（3D）体积; 检测所述3D体积中感兴趣的目标的最佳边界框，其中所述最佳边界框由包括在所述3D体积中的空间和时间信息的多个参数指定; 并从最佳边界框确定感兴趣的目标。

公开(公告)号：US20120076380A1

公开(公告)日：2012-03-29

申请号：US13210497

申请日：2011-08-16

Applicant: Jens Gühring ,  Marie-Pierre Jolly ,  Hui Xue

Inventor： Jens Gühring ,  Marie-Pierre Jolly ,  Hui Xue

IPC: G06K9/00

CPC classification number: G01R33/56316 ,  A61B5/0263 ,  A61B5/055 ,  G01R33/5608

Abstract: A method for correcting the background phase in magnetic resonance phase contrast flow images includes providing a time series of velocity encoded magnetic resonance images of a patient, where the time series of velocity encoded images comprises for each time point a phase contrast image where a pixel intensity is proportional to a flow velocity, measuring a change of intensity for each pixel over the time series of phase contrast images, identifying pixels with a low measure of temporal change as stationary pixels, and calculating a correction field for the stationary pixels, where the correction field represents a background phase to be subtracted from the phase contrast image.

Abstract translation: 用于校正磁共振相位对比流图像中的背景相位的方法包括提供患者的速度编码的磁共振图像的时间序列，其中速度编码图像的时间序列包括每个时间点的像素强度 与流速成比例，测量在相位对比图像的时间序列上的每个像素的强度变化，将以时间变化的低度量度的像素识别为静止像素，以及计算用于静止像素的校正场，其中校正 场表示从相位差图像中减去的背景相位。

公开(公告)号：US08897519B2

公开(公告)日：2014-11-25

申请号：US13210497

申请日：2011-08-16

Applicant: Jens Gühring ,  Marie-Pierre Jolly ,  Hui Xue

Inventor： Jens Gühring ,  Marie-Pierre Jolly ,  Hui Xue

IPC: G06K9/00 ,  G01R33/563 ,  A61B5/026 ,  A61B5/055 ,  G01R33/56

CPC classification number: G01R33/56316 ,  A61B5/0263 ,  A61B5/055 ,  G01R33/5608

Abstract: A method for correcting the background phase in magnetic resonance phase contrast flow images includes providing a time series of velocity encoded magnetic resonance images of a patient, where the time series of velocity encoded images comprises for each time point a phase contrast image where a pixel intensity is proportional to a flow velocity, measuring a change of intensity for each pixel over the time series of phase contrast images, identifying pixels with a low measure of temporal change as stationary pixels, and calculating a correction field for the stationary pixels, where the correction field represents a background phase to be subtracted from the phase contrast image.

Abstract translation: 用于校正磁共振相位对比流图像中的背景相位的方法包括提供患者的速度编码的磁共振图像的时间序列，其中速度编码图像的时间序列包括每个时间点的像素强度 与流速成比例，测量在相位对比图像的时间序列上的每个像素的强度变化，将以时间变化的低度量度的像素识别为静止像素，以及计算用于静止像素的校正场，其中校正 场表示从相位差图像中减去的背景相位。

公开(公告)号：US08848990B2

公开(公告)日：2014-09-30

申请号：US13237198

申请日：2011-09-20

Applicant: Hui Xue ,  Saurabh Shah ,  Jens Gühring ,  Andreas Greiser ,  Christophe Chefd'hotel ,  Christoph Guetter ,  Marie-Pierre Jolly ,  Sven Zuehlsdorff

Inventor： Hui Xue ,  Saurabh Shah ,  Jens Gühring ,  Andreas Greiser ,  Christophe Chefd'hotel ,  Christoph Guetter ,  Marie-Pierre Jolly ,  Sven Zuehlsdorff

IPC: G06K9/00 ,  G06T5/50 ,  G06T7/00 ,  G01R33/44 ,  G01R33/565

CPC classification number: G06T5/50 ,  G01R33/448 ,  G01R33/56509 ,  G06T7/30 ,  G06T2207/10088 ,  G06T2207/20201 ,  G06T2207/30048

Abstract: A method for performing motion compensation in a series of magnetic resonance (MR) images includes acquiring a set of MR image frames spanning different points along an MR recovery curve. A motion-free synthetic image is generated for each of the acquired MR image frames using prior knowledge pertaining to an MR recovery curve. Each of the acquired MR images is registered to its corresponding generated synthetic images. Motion within each of the acquired MR image is corrected based on its corresponding generated synthetic image that has been registered thereto.

Abstract translation: 用于在一系列磁共振（MR）图像中执行运动补偿的方法包括获取沿着MR恢复曲线横跨不同点的一组MR图像帧。 使用与MR恢复曲线相关的先前知识，为每个所获取的MR图像帧生成无运动合成图像。 所获取的MR图像中的每一个被注册到其对应的生成的合成图像。 基于其对应的生成的已经被注册的合成图像来校正所获取的MR图像的每一个内的运动。

公开(公告)号：US08811699B2

公开(公告)日：2014-08-19

申请号：US13234694

申请日：2011-09-16

Applicant: Xiaoguang Lu ,  Jens Gühring ,  Hui Xue ,  Marie-Pierre Jolly ,  Christoph Guetter ,  Bogdan Georgescu ,  Sven Zuehlsdorff ,  Arne Littmann

Inventor： Xiaoguang Lu ,  Jens Gühring ,  Hui Xue ,  Marie-Pierre Jolly ,  Christoph Guetter ,  Bogdan Georgescu ,  Sven Zuehlsdorff ,  Arne Littmann

IPC: G06K9/00

CPC classification number: G06K9/4609 ,  G06K2209/051 ,  G06T7/11 ,  G06T7/143 ,  G06T7/194 ,  G06T2207/10088 ,  G06T2207/20164 ,  G06T2207/30048

Abstract: A method including receiving an image sequence, wherein the image sequence includes a plurality of two-dimensional (2D) image frames of an organ arranged in a time sequence; constructing a three-dimensional (3D) volume by stacking a plurality of the 2D image frames in time order; detecting a best bounding box for a target of interest in the 3D volume, wherein the best bounding box is specified by a plurality of parameters including spatial and temporal information contained in the 3D volume; and determining the target of interest from the best bounding box.

Abstract translation: 一种包括接收图像序列的方法，其中所述图像序列包括以时间顺序排列的器官的多个二维（2D）图像帧; 通过以时间顺序堆叠多个2D图像帧来构造三维（3D）体积; 检测所述3D体积中感兴趣的目标的最佳边界框，其中所述最佳边界框由包括在所述3D体积中的空间和时间信息的多个参数指定; 并从最佳边界框确定感兴趣的目标。

公开(公告)号：US08792699B2

公开(公告)日：2014-07-29

申请号：US13239530

申请日：2011-09-22

Applicant: Christoph Guetter ,  Jens Gühring ,  Marie-Pierre Jolly ,  Xiaoguang Lu ,  Hui Xue ,  Jeremy Collins ,  Peter Weale

Inventor： Christoph Guetter ,  Jens Gühring ,  Marie-Pierre Jolly ,  Xiaoguang Lu ,  Hui Xue ,  Jeremy Collins ,  Peter Weale

IPC: G06K9/00

CPC classification number: G01R33/56316

Abstract: A method for clinical parameter derivation and adaptive flow acquisition within a sequence of magnetic resonance images includes commencing an acquisition of a sequence of images. One or more landmarks are automatically detected from within one or more images of the sequence of images. The detected one or more landmarks are propagated across subsequent images of the sequence of images. A plane is fitted to the propagation of landmarks. The positions of landmarks or alternatively the position of the fitted plane within the sequence of images is used for derivation of clinical parameters such as tissue velocities and/or performing adaptive flow acquisitions to measure blood flow properties.

Abstract translation: 在磁共振图像序列内的临床参数推导和自适应流采集的方法包括开始获取图像序列。 在图像序列的一个或多个图像内自动检测一个或多个地标。 检测到的一个或多个地标在图像序列的后续图像中传播。 一个平面适合于地标的传播。 地标的位置或替代地，图像序列内的拟合平面的位置用于推导诸如组织速度的临床参数和/或执行自适应流采集以测量血流特性。

公开(公告)号：US08578754B2

公开(公告)日：2013-11-12

申请号：US13010795

申请日：2011-01-21

Applicant: Jinchuan Zhang ,  Ying Tang ,  Xuan Tang ,  Zhonglin Song ,  Dejian Zhai ,  Hui Xue

Inventor： Jinchuan Zhang ,  Ying Tang ,  Xuan Tang ,  Zhonglin Song ,  Dejian Zhai ,  Hui Xue

IPC: G01N33/18 ,  G01N1/22 ,  G01N1/12

CPC classification number: G01N7/16 ,  G01N33/225

Abstract: The present invention relates to an adsorbed gas content measuring instrument and its testing method. The instrument comprises sealed cylinders, gas collecting graduated canisters and a test box, wherein the sealed cylinders are provided with valves, the gas collecting graduated canisters are equipped with drain hole adjustment valves and vent hole switching valves fit for the valve ports, and there is a heating element and a temperature controller in the test box. The method is mainly as follows: put gas-contained samples and saturated brine into the sealed cylinder, seal the cylinder, feed water in the test box and heat the box, place the sealed cylinder into the water bath of the test box, introduce saturated brine into the gas collecting graduated canister, connect the canister and cylinder, open the drain hole of the gas collecting graduated canister, record the liquid level of the graduated canister and cut off the connection after the test. The present invention has a compact structure, small volume, good gas tightness, accurate measurement, uniform heating and simple testing operation, is easy to move and carry, and suitable for field application. It can be specially used for collecting and measuring various gases, especially small-volume gas, thus it is more practical in applications.

Abstract translation: 本发明涉及吸附气体含量测量仪及其测试方法。 该仪器包括密封圆筒，气体收集分级罐和试验箱，其中密封圆柱体设有阀，气体收集分级罐配有排水孔调节阀和适合阀口的排气孔切换阀， 加热元件和温度控制器在测试箱中。 方法主要如下：将含气样品和饱和盐水放入密封圆筒中，密封圆筒，将试验箱内的水送入箱中，加热箱体，将密封圆筒放入试验箱的水浴中，引入饱和 盐水进入气体收集分级罐，连接罐和气瓶，打开集气分级罐的排水孔，记录分级罐的液位，并在试验后切断连接。 本发明结构紧凑，体积小，气密性好，测量准确，加热均匀，测试操作简单，易于移动携带，适用于现场应用。 它可以专门用于收集和测量各种气体，特别是小体积的气体，因此在应用中更为实用。