公开(公告)号：US10676842B2

公开(公告)日：2020-06-09

申请号：US16670340

申请日：2019-10-31

Applicant: Inscripta, Inc.

Inventor： Stephen Federowicz ,  Deanna Church ,  Michael Graige

IPC: C12N15/10 ,  C40B50/06 ,  C40B70/00 ,  C40B40/02 ,  C40B20/04 ,  C12N15/90 ,  C12N15/85 ,  C12N9/22 ,  C07K14/74 ,  C07K16/28 ,  C40B40/10 ,  C40B30/04 ,  C12N15/81

Abstract: The present disclosure provides instrumentation and automated methods for creating cell surface display libraries, where the cells of the library display engineered peptides on their cell surfaces for identification of antigens that bind to T-cell receptors. The engineered peptides may be putative antigens or binding regions of the T-cell receptors.

公开(公告)号：US20190323147A1

公开(公告)日：2019-10-24

申请号：US16392605

申请日：2019-04-23

Applicant: Inscripta, Inc.

Inventor： Stephen Federowicz ,  Deanna Church ,  Michael Graige

IPC: C40B50/06 ,  C12N9/22 ,  C07K16/28 ,  C40B40/10 ,  C40B30/04

Abstract: The present disclosure provides instrumentation and automated methods for creating cell surface display libraries, where the cells of the library display engineered peptides on their cell surfaces for identification of antigens that bind to T-cell receptors. The engineered peptides may be putative antigens or binding regions of the T-cell receptors.