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公开(公告)号:US20110066230A1
公开(公告)日:2011-03-17
申请号:US12562010
申请日:2009-09-17
申请人: Andrew Schally , Jozsef Varga , Marta Zarandi , Ren Zhi Cai , Norman L. Block
发明人: Andrew Schally , Jozsef Varga , Marta Zarandi , Ren Zhi Cai , Norman L. Block
CPC分类号: A61K9/0019 , A61K38/00 , C07K14/60
摘要: Novel fluorinated synthetic analogs of hGH-RH(1-30)NH2 that inhibit the release of growth hormone from the pituitary in mammals as well as inhibit the proliferation of human cancers through a direct effect on the cancer cells, and to therapeutic compositions containing these novel peptides and their use.
摘要翻译: hGH-RH(1-30)NH2的新型氟化合成类似物,其抑制哺乳动物垂体中生长激素的释放,并且通过对癌细胞的直接作用抑制人类癌症的增殖,以及含有这些的治疗组合物 新型肽及其用途。
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公开(公告)号:US07452865B2
公开(公告)日:2008-11-18
申请号:US10566776
申请日:2004-07-26
申请人: Andrew V. Schally , Jozsef Varga , Marta Zarandi , Ren Zhi Cai
发明人: Andrew V. Schally , Jozsef Varga , Marta Zarandi , Ren Zhi Cai
摘要: There is provided a novel series of synthetic antagonistic analogs of hGH-RH(1-29)NH2. These analogs inhibit the activity of endogenous hGH-RH on the pituitary GH-RH receptors, and therefore prevent the release of growth hormone. The analogs also inhibit the proliferation of human cancers through a direct effect on the cancer cells. The higher inhibitory potencies of the new analogs, as compared to previously described ones, results from replacement of various amino acids.
摘要翻译: 提供了一系列hGH-RH(1-29)NH 2的合成拮抗类似物。 这些类似物抑制内源性hGH-RH对垂体GH-RH受体的活性,因此防止生长激素的释放。 类似物还通过对癌细胞的直接作用来抑制人类癌症的增殖。 与之前描述的相比,新类似物的更高的抑制效力来自各种氨基酸的替换。
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公开(公告)号:US20070283022A1
公开(公告)日:2007-12-06
申请号:US11486844
申请日:2006-07-14
申请人: Zsolt Rajko , Gabor Jaro , Andras Szeman , Jozsef Varga
发明人: Zsolt Rajko , Gabor Jaro , Andras Szeman , Jozsef Varga
IPC分类号: G06F15/16
摘要: A method of allocating one of a plurality of call state control functions to a subscriber, the method comprising: sending registration requests to the plurality of call state control functions; storing information regarding the availability of the call state control functions in response to unsuccessful registration requests; and determining a call state control function for the subscriber in dependence on said stored information.
摘要翻译: 一种向用户分配多个呼叫状态控制功能之一的方法,该方法包括:向多个呼叫状态控制功能发送注册请求; 响应于不成功的注册请求存储关于呼叫状态控制功能的可用性的信息; 以及根据所述存储的信息确定用户的呼叫状态控制功能。
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公开(公告)号:US20070186101A1
公开(公告)日:2007-08-09
申请号:US11593077
申请日:2006-11-06
申请人: Zsolt Rajko , Jozsef Varga
发明人: Zsolt Rajko , Jozsef Varga
IPC分类号: H04L9/00
CPC分类号: H04L63/123 , H04L63/0823 , H04L67/14 , H04L67/147
摘要: A network element for handling a trusted relationship in an IP multimedia subsystem, the network element includes a receiving unit for receiving a message from another entity, wherein the message includes a header. The network element also includes a determining for determining that an entity from which the message is received is a predefined trusted entity. The header of the message includes information for identifying whether or not the entity from which the message is received is a predefined trusted entity. The network element also includes a processing unit for using contents of the header, from the entity that is determined to be a predefined trusted entity, for applications implemented by the network element.
摘要翻译: 一种用于处理IP多媒体子系统中的信任关系的网络元件,所述网络单元包括用于从另一实体接收消息的接收单元,其中所述消息包括报头。 网络元件还包括用于确定从其接收消息的实体是预定义的可信实体的确定。 消息的报头包括用于识别接收到消息的实体是否是预定义的可信实体的信息。 该网络元件还包括一个处理单元,用于对由网络元件实现的应用使用从被确定为预定义的可信实体的实体中使用报头的内容。
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公开(公告)号:US20070043876A1
公开(公告)日:2007-02-22
申请号:US11292753
申请日:2005-12-01
申请人: Jozsef Varga , Son Phan-Anh , Gyorgy Wolfner
发明人: Jozsef Varga , Son Phan-Anh , Gyorgy Wolfner
IPC分类号: G06F15/16
CPC分类号: H04L29/12537 , H04L29/06027 , H04L29/12471 , H04L29/125 , H04L61/2553 , H04L61/2564 , H04L61/2578 , H04L65/1006
摘要: The present invention relates to a method, system, session control device and computer program product for maintaining a binding relationship in an address translation function (20) used for providing a translation between a first address used for addressing a device (10) from inside a data network and a second address used for addressing the device (10) from outside the data network. At a predetermined timing, a dedicated signaling message having at least an unknown portion not defined in the data network is generated, e.g. at a session control device (30), and transmitted to the device so as to initiate transmission of a predetermined response message via the address translation function (20). Thereby, the response message can easily be discriminated and does not require any substantial processing.
摘要翻译: 本发明涉及一种用于在地址转换功能(20)中维持绑定关系的方法,系统,会话控制装置和计算机程序产品,所述地址转换功能用于在用于从设备(10)的内部寻址 数据网络和用于从数据网络外部寻址设备(10)的第二地址。 在预定的定时,产生具有至少未在数据网络中定义的未知部分的专用信令消息,例如, 在会话控制设备(30)处,并且被发送到设备,以便经由地址转换功能(20)发起预定响应消息的发送。 因此,可以容易地区分响应消息,并且不需要任何实质的处理。
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公开(公告)号:US5390526A
公开(公告)日:1995-02-21
申请号:US150661
申请日:1993-11-09
申请人: Gyorgy Balazs , Sandor Cebely , Jeno Jadi, deceased , Janos Kusz , Andras Monus , Lajos Nagy , Jozsef Varga
发明人: Gyorgy Balazs , Sandor Cebely , Jeno Jadi, deceased , Janos Kusz , Andras Monus , Lajos Nagy , Jozsef Varga
摘要: A double profile drawing tool includes a mandrel having a profile drawing die formed therein with first and second portions extending in opposite directions, associated therewith. The mandrel is disposed in a supported surrounding manner within a structure including a housing body and an embedding component. The embedding component is securely fixed within the housing body by way of a support plate which is joined to the housing body in a shrink fit manner. The structure formed by the housing body, support plate, with the mandrel and embedding component contained therein, is then securely mounted within a U-shaped outer housing member. First and second tapered openings are formed on opposite sides and along the longitudinal axis of the double profile drawing tool, such tapered openings providing communication to the first and second portions of the profile drawing die from opposite directions. The double profile drawing tool can be reversed for operation in an opposite direction once it has been determined that one portion of the profile drawing die has been worn. In either direction of operation, the mandrel is positively supported so as to prevent movement and to insure that a substantial portion of loading forces are directed away from the profile drawing die.
摘要翻译: 双轮廓拉伸工具包括具有形成在其中的与其相反的相反方向延伸的第一和第二部分的轮廓拉伸模头的心轴。 心轴以支撑的周围方式设置在包括壳体和嵌入部件的结构内。 嵌入部件通过支撑板牢固地固定在壳体内,该支撑板以收缩配合的方式接合到壳体。 然后将壳体,支撑板,其中容纳有心轴和嵌入部件的结构形成的结构牢固地安装在U形外壳体内。 第一和第二锥形开口形成在双轮廓拉伸工具的相对侧和纵向轴线上,这样的锥形开口提供与轮廓拉伸模具的第一和第二部分相反的方向的连通。 一旦已经确定轮廓拉伸模具的一部分已经被磨损,双轮廓拉伸工具可以反转以在相反的方向上操作。 在任何一个操作方向上,心轴被可靠地支撑,以防止移动并且确保大部分的加载力被引导离开轮廓拉拔模具。
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公开(公告)号:US08850012B2
公开(公告)日:2014-09-30
申请号:US11889991
申请日:2007-08-17
申请人: Robert Ropolyi , Jozsef Varga
发明人: Robert Ropolyi , Jozsef Varga
IPC分类号: G06F15/16
CPC分类号: H04L65/1016 , H04L12/14 , H04L65/1006
摘要: A network node, such as a network control node like a CSCF or an application server, executing forking forward only the first successful response message arriving from a forking branch, which enables the charging function in the forking node and in nodes in the backward direction from this point to apply charges only for the “winning” branch. By including a special Reason header sent in a BYE request of “unused” successfully contacted branches, charging function in nodes in the forward direction from the forking point are allowed to suppress charges for such unused branches. This is applicable both for online and offline charging methods as defined, for example, by 3GPP.
摘要翻译: 网络节点,诸如像CSCF或应用服务器的网络控制节点,仅执行从分支分支到达的第一成功响应消息,从而能够在叉形节点和后向方向上的节点中进行计费功能 这一点只适用于“胜利”分支。 通过在BYE请求中包含“未使用”成功接通的分支发送的特殊原因报头,允许从分支点向正方向的节点中的计费功能抑制这些未使用分支的收费。 这适用于例如3GPP定义的在线和离线计费方法。
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公开(公告)号:US08306199B2
公开(公告)日:2012-11-06
申请号:US11907781
申请日:2007-10-17
申请人: Robert Ropolyi , Jozsef Varga
发明人: Robert Ropolyi , Jozsef Varga
CPC分类号: H04M15/00
摘要: An accounting function in a network between originating and terminating networks is disclosed. A transit network node is provided with an appropriate indication regarding its role in inter-operator accounting, for example if it should act as an intermediary node or not. A transit network node configured to function in an appropriate manner to function in an intermediary role in the inter-operator accounting is also disclosed. The intermediary role can be optional.
摘要翻译: 公开了在始发和终端网络之间的网络中的计费功能。 向运输网络节点提供关于其在运营商间会计中的作用的适当指示,例如,如果它应当充当中间节点。 还公开了一种被配置为以适当的方式在运营商间会计中发挥中间作用的运输网络节点。 中介角色可以是可选的。
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公开(公告)号:US20120218920A1
公开(公告)日:2012-08-30
申请号:US13509319
申请日:2010-10-04
申请人: Jozsef Varga , Andras Szeman , Andras Pasztor
发明人: Jozsef Varga , Andras Szeman , Andras Pasztor
CPC分类号: H04W4/22 , H04L65/1016 , H04L65/1069 , H04W4/90 , H04W76/50
摘要: The invention relates to an apparatus, method and a computer program product for establishing a request for a session by an application server, determining by an emergency related local service function that the session includes an emergency session, wherein the emergency related local service function is co-located at the application server, and, transmitting the request for the session to an emergency call state control function of the internet protocol multimedia subsystem based on the determination.
摘要翻译: 本发明涉及一种用于由应用服务器建立会话请求的装置,方法和计算机程序产品,通过紧急相关的本地服务功能确定该会话包括紧急会话,其中紧急相关的本地服务功能是co 定位在应用服务器处,并且基于该确定,将会话请求发送到因特网协议多媒体子系统的紧急呼叫状态控制功能。
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公开(公告)号:US08227421B2
公开(公告)日:2012-07-24
申请号:US12562010
申请日:2009-09-17
申请人: Andrew Schally , Jozsef Varga , Marta Zarandi , Ren Zhi Cai
发明人: Andrew Schally , Jozsef Varga , Marta Zarandi , Ren Zhi Cai
CPC分类号: A61K9/0019 , A61K38/00 , C07K14/60
摘要: Novel fluorinated synthetic analogs of hGH-RH(1-30)NH2 that inhibit the release of growth hormone from the pituitary in mammals as well as inhibit the proliferation of human cancers through a direct effect on the cancer cells, and to therapeutic compositions containing these novel peptides and their use.
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