-
公开(公告)号：US08017783B2
公开(公告)日：2011-09-13
申请号：US11899181
申请日：2007-09-05
申请人： Mathai Mammen , Yu-Hua Ji , YongQi Mu , Craig Husfeld , Li Li
发明人： Mathai Mammen , Yu-Hua Ji , YongQi Mu , Craig Husfeld , Li Li
IPC分类号： C07D401/12
CPC分类号： C07D211/62 , A61K9/124 , A61K9/1623 , A61K9/1652 , A61K31/4545 , A61K45/06 , C07D401/12
摘要： This invention provides compounds of formula I: wherein a, b, c, d, m, n, p, s, t, W, Ar1, R1, R2, R3, R4, R6, R7, and R8 are as defined in the specification. The compounds of formula I are muscarinic receptor antagonists. The invention also provides pharmaceutical compositions containing such compounds, processes and intermediates for preparing such compounds and methods of using such compounds to treat pulmonary disorders.
-
公开(公告)号：US07851632B2
公开(公告)日：2010-12-14
申请号：US11880048
申请日：2007-07-19
申请人： Mathai Mammen , Yu-Hua Ji , YongQi Mu , Craig Husfeld , Li Li
发明人： Mathai Mammen , Yu-Hua Ji , YongQi Mu , Craig Husfeld , Li Li
IPC分类号： A61K31/05 , C07D411/08
CPC分类号： C07D211/46 , C07D401/12 , C07D405/12 , C07D409/12
摘要： This invention provides compounds of formula I: wherein a, b, c, m, p, s, t, W, Ar1, X1, R1, R2, R3, R4, R6, and R7 are as defined in the specification. The compounds of formula I are muscarinic receptor antagonists. The invention also provides pharmaceutical compositions containing such compounds, processes and intermediates for preparing such compounds and methods of using such compounds to treat pulmonary disorders.
摘要翻译： 本发明提供式I化合物：其中a，b，c，m，p，s，t，W，Ar1，X1，R1，R2，R3，R4，R6和R7如说明书中所定义。 式I化合物是毒蕈碱受体拮抗剂。 本发明还提供含有这些化合物的药物组合物，用于制备这些化合物的方法和中间体以及使用这些化合物治疗肺部疾病的方法。
-
公开(公告)号：US07288657B2
公开(公告)日：2007-10-30
申请号：US11077433
申请日：2005-03-10
申请人： Mathai Mammen , Yu-Hua Ji , YongQi Mu , Craig Husfeld , Li Li
发明人： Mathai Mammen , Yu-Hua Ji , YongQi Mu , Craig Husfeld , Li Li
IPC分类号： C07D211/00 , C07D405/00 , C07D409/00
CPC分类号： C07D211/62 , A61K9/124 , A61K9/1623 , A61K9/1652 , A61K31/4545 , A61K45/06 , C07D401/12
摘要： This invention provides compounds of formula I: wherein a, b, c, d, m, n, p, s, t, W, Ar1, R1, R2, R3, R4, R6, R7, and R8 are as defined in the specification. The compounds of formula I are muscarinic receptor antagonists. The invention also provides pharmaceutical compositions containing such compounds, processes and intermediates for preparing such compounds and methods of using such compounds to treat pulmonary disorders.
摘要翻译： 本发明提供式I化合物：其中a，b，c，d，m，n，p，s，t，W，Ar 1，R 1，R R 2，R 3，R 4，R 6，R 7和/或R 4， R 8如本说明书中所定义。 式I的化合物是毒蕈碱受体拮抗剂。 本发明还提供含有这些化合物的药物组合物，用于制备这些化合物的方法和中间体以及使用这些化合物治疗肺部疾病的方法。
-
公开(公告)号：US20050203138A1
公开(公告)日：2005-09-15
申请号：US11076796
申请日：2005-03-10
申请人： Mathai Mammen , Yu-Hua Ji , YongQi Mu , Craig Husfeld , Li Li
发明人： Mathai Mammen , Yu-Hua Ji , YongQi Mu , Craig Husfeld , Li Li
IPC分类号： A61K31/445 , C07D211/26 , C07D211/46 , C07D401/12 , C07D405/12 , C07D409/12
CPC分类号： C07D211/46 , C07D401/12 , C07D405/12 , C07D409/12
摘要： This invention provides compounds of formula I: wherein a, b, c, m, p, s, t, W, Ar1, X1, R1, R2, R3, R4, R6, and R7 are as defined in the specification. The compounds of formula I are muscarinic receptor antagonists. The invention also provides pharmaceutical compositions containing such compounds, processes and intermediates for preparing such compounds and methods of using such compounds to treat pulmonary disorders.
-
公开(公告)号：US20050203133A1
公开(公告)日：2005-09-15
申请号：US11077433
申请日：2005-03-10
申请人： Mathai Mammen , Yu-Hua Ji , YongQi Mu , Craig Husfeld , Li Li
发明人： Mathai Mammen , Yu-Hua Ji , YongQi Mu , Craig Husfeld , Li Li
IPC分类号： A61K31/4545 , C07D211/62 , C07D41/02
CPC分类号： C07D211/62 , A61K9/124 , A61K9/1623 , A61K9/1652 , A61K31/4545 , A61K45/06 , C07D401/12
摘要： This invention provides compounds of formula I: wherein a, b, c, d, m, n, p, s, t, W, Ar1, R1, R2, R3, R4, R6, R7, and R8 are as defined in the specification. The compounds of formula I are muscarinic receptor antagonists. The invention also provides pharmaceutical compositions containing such compounds, processes and intermediates for preparing such compounds and methods of using such compounds to treat pulmonary disorders.
摘要翻译： 本发明提供式I化合物：其中a，b，c，d，m，n，p，s，t，W，Ar 1，R 1，R R 2，R 3，R 4，R 6，R 7和/或R 4， R 8如本说明书中所定义。 式I化合物是毒蕈碱受体拮抗剂。 本发明还提供含有这些化合物的药物组合物，用于制备这些化合物的方法和中间体以及使用这些化合物治疗肺部疾病的方法。
-
公开(公告)号：US07521041B2
公开(公告)日：2009-04-21
申请号：US11974318
申请日：2007-10-12
申请人： Mathai Mammen , Yu-Hua Ji , YongQi Mu , Craig Husfeld , Li Li
发明人： Mathai Mammen , Yu-Hua Ji , YongQi Mu , Craig Husfeld , Li Li
CPC分类号： C07D211/62 , A61K9/124 , A61K9/1623 , A61K9/1652 , A61K31/4545 , A61K45/06 , C07D401/12
摘要： This invention provides compounds of formula I: wherein a, b, c, d, m, n, p, s, t, W, Ar1, R1, R2, R3, R4, R6, R7, and R8 are as defined in the specification. The compounds of formula I are muscarinic receptor antagonists. The invention also provides pharmaceutical compositions containing such compounds, processes and intermediates for preparing such compounds and methods of using such compounds to treat pulmonary disorders.
-
公开(公告)号：US20060205946A1
公开(公告)日：2006-09-14
申请号：US11372251
申请日：2006-03-09
申请人： Yu-Hua Ji , Craig Husfeld , Mathai Mammen , YongQi Mu , Eric Stangeland
发明人： Yu-Hua Ji , Craig Husfeld , Mathai Mammen , YongQi Mu , Eric Stangeland
IPC分类号： A61K31/496 , A61K31/454 , C07D403/02
CPC分类号： C07D211/58 , C07D211/46 , C07D211/62 , C07D401/06 , C07D401/12 , C07D401/14 , C07D405/12 , C07D405/14 , C07D487/08 , C07D487/10
摘要： The invention provides compounds of formula I: wherein a, b, c, d, f, W, Q, Y, R1, R2, and R3 are as defined in the specification. The compounds of formula I are muscarinic receptor antagonists. The invention also provides pharmaceutical compositions containing such compounds, processes and intermediates for preparing such compounds and methods of using such compounds to treat pulmonary disorders.
摘要翻译： 本发明提供式I化合物：其中a，b，c，d，f，w，Q，Y，R 1，R 2和R 2， 3 如说明书中所定义。 式I化合物是毒蕈碱受体拮抗剂。 本发明还提供含有这些化合物的药物组合物，用于制备这些化合物的方法和中间体以及使用这些化合物治疗肺部疾病的方法。
-
公开(公告)号：US07550595B2
公开(公告)日：2009-06-23
申请号：US11880002
申请日：2007-07-19
申请人： Mathai Mammen , Yu-Hua Ji , YongQi Mu , Craig Husfeld , Li Li
发明人： Mathai Mammen , Yu-Hua Ji , YongQi Mu , Craig Husfeld , Li Li
IPC分类号： C07D221/02 , C07D405/00 , C07D211/00
CPC分类号： C07D211/62 , A61K9/124 , A61K9/1623 , A61K9/1652 , A61K31/4545 , A61K45/06 , C07D401/12
摘要： This invention provides compounds of formula I: wherein a, b, c, d, m, n, p, s, t, W, Ar1, R1, R2, R3, R4, R6, R7, and R8 are as defined in the specification. The compounds of formula I are muscarinic receptor antagonists. The invention also provides pharmaceutical compositions containing such compounds, processes and intermediates for preparing such compounds and methods of using such compounds to treat pulmonary disorders.
-
公开(公告)号：US20070265310A1
公开(公告)日：2007-11-15
申请号：US11880048
申请日：2007-07-19
申请人： Mathai Mammen , Yu-Hua Ji , YongQi Mu , Craig Husfeld , Li Li
发明人： Mathai Mammen , Yu-Hua Ji , YongQi Mu , Craig Husfeld , Li Li
IPC分类号： A61K31/445 , A61K31/4525 , A61K31/4535 , A61K31/4545 , A61P11/06 , A61P11/08 , C07D211/44
CPC分类号： C07D211/46 , C07D401/12 , C07D405/12 , C07D409/12
摘要： This invention provides compounds of formula I: wherein a, b, c, m, p, s, t, W, Ar1, X1, R1, R2, R3, R4, R6, and R7 are as defined in the specification. The compounds of formula I are muscarinic receptor antagonists. The invention also provides pharmaceutical compositions containing such compounds, processes and intermediates for preparing such compounds and methods of using such compounds to treat pulmonary disorders.
-
公开(公告)号：US07910608B2
公开(公告)日：2011-03-22
申请号：US11879835
申请日：2007-07-19
申请人： Mathai Mammen , Yu-Hua Ji , YongQi Mu , Craig Husfeld , Li Li
发明人： Mathai Mammen , Yu-Hua Ji , YongQi Mu , Craig Husfeld , Li Li
IPC分类号： A61K31/445 , C07D221/08
CPC分类号： C07D211/62 , A61K9/124 , A61K9/1623 , A61K9/1652 , A61K31/4545 , A61K45/06 , C07D401/12
摘要： This invention provides compounds of formula I: wherein a, b, c, d, m, n, p, s, t, W, Ar1, R1, R2, R3, R4, R6, R7, and R8 are as defined in the specification. The compounds of formula I are muscarinic receptor antagonists. The invention also provides pharmaceutical compositions containing such compounds, processes and intermediates for preparing such compounds and methods of using such compounds to treat pulmonary disorders.
摘要翻译： 本发明提供式I化合物：其中a，b，c，d，m，n，p，s，t，W，Ar1，R1，R2，R3，R4，R6，R7和R8如 规范。 式I化合物是毒蕈碱受体拮抗剂。 本发明还提供含有这些化合物的药物组合物，用于制备这些化合物的方法和中间体以及使用这些化合物治疗肺部疾病的方法。
-
-
-
-
-
-
-
-
-
搜索结果
187 条记录 (耗时 0.04 秒)
