公开(公告)号：US4883765A

公开(公告)日：1989-11-28

申请号：US91218

申请日：1987-08-28

Applicant: Ilana Tamir ,  Ben-Zion Kidron ,  Lynn Wang ,  Michael Inbar

Inventor： Ilana Tamir ,  Ben-Zion Kidron ,  Lynn Wang ,  Michael Inbar

IPC: B01D15/00 ,  C12Q1/60 ,  G01N33/92

CPC classification number: B01D15/00 ,  C12Q1/60 ,  G01N33/92 ,  G01N2800/044 ,  Y10T436/106664

Abstract: A method, device and kit for the quantitative determination of lipoprotein components, especially cholesterol and triglycerides, in body fluids, especially human serum, plasma or whole blood utilizing the selective adsorption of lipoproteins on particulate silica. This selective adsorption is also useful for the quantitative separation of lipoproteins from samples of whole blood for diagnostic purposes.

Abstract translation: 一种利用脂蛋白在颗粒状二氧化硅上选择性吸附来定量测定体液，特别是人血清，血浆或全血中脂蛋白成分，特别是胆固醇和甘油三酯的方法，装置和试剂盒。 这种选择性吸附也可用于从全血样品中定量分离脂蛋白用于诊断目的。

公开(公告)号：US4131800A

公开(公告)日：1978-12-26

申请号：US774215

申请日：1977-03-03

Applicant: Avraham Bruck ,  Michael Inbar

Inventor： Avraham Bruck ,  Michael Inbar

IPC: G01N21/64 ,  G01N21/38

CPC classification number: G01N21/6445

Abstract: The normality of a cell labelled with a lipid soluble fluorescent dye and excited with a beam of polarized light can be evaluated by measuring the time dependence of the state of polarization of fluorescence emitted by the cell which is determined by simultaneously measuring the intensities of fluorescence polarized in directions parallel and perpendicular to the direction of polarization of the excitation beam.The state of polarization of a cell changes markedly as a function of excitation time when the cell is abnormal (i.e., malignant), while the state of polarization of a cell remains substantially constant when the cell is normal. Classification of cells in a population by way of the stability of the state of polarization provides guidance in determining the presence of malignancy in the population.

Abstract translation: 用脂质可溶性荧光染料标记并用偏振光束激发的细胞的正常性可以通过测量由细胞发射的荧光的偏振态的时间依赖性来评估，其通过同时测量荧光极化强度 在与激发光束的偏振方向平行且垂直的方向上。