公开(公告)号：US20130307952A1

公开(公告)日：2013-11-21

申请号：US13950376

申请日：2013-07-25

Applicant: OLYMPUS CORPORATION

Inventor： Yasushige ISHIHARA

IPC: G01N21/64

CPC classification number: G01N21/6456 ,  A61B1/00006 ,  A61B1/00009 ,  A61B1/043 ,  A61B5/0071 ,  G01N21/6486 ,  H04N5/2353 ,  H04N5/347 ,  H04N2005/2255

Abstract: Observation is performed at a more appropriate sensitivity without causing deterioration of the image quality. Provided is a fluorescence observation apparatus including an excitation light source that emits excitation light to be radiated onto an imaging subject; a fluorescence-image acquisition portion that is provided with an imaging device that acquires fluorescence images by capturing fluorescence generated at the imaging subject due to the irradiation with the excitation light emitted from the excitation light source; and a sensitivity adjusting portion that adjusts an number of pixels for binning summing and/or an exposure time for the imaging device on the basis of luminance information of the fluorescence image acquired by the imaging device of the fluorescence-image acquisition portion so that an SN ratio of the fluorescence image becomes equal to or higher than a predetermined threshold.

Abstract translation: 以更适当的灵敏度进行观察，而不会导致图像质量的劣化。 本发明提供一种荧光观察装置，其包括：发射激发光的激发光源，照射到摄像对象上; 荧光图像获取部分，其设置有成像装置，其通过从由激发光源发射的激发光的照射捕获在成像对象产生的荧光来获取荧光图像; 以及灵敏度调整部，其基于由所述荧光图像获取部的摄像装置获取的荧光图像的亮度信息，调整所述摄像装置的叠加加和/或曝光时间的像素数，使得SN 荧光图像的比例变得等于或高于预定阈值。