公开(公告)号：US10646321B2

公开(公告)日：2020-05-12

申请号：US15384435

申请日：2016-12-20

Applicant: Sofradim Production

Inventor： Sebastien Francois ,  Michel Therin ,  Nicolas Prost

IPC: A61F2/00

Abstract: The present invention relates to a prosthesis (1) for hernia repair comprising a reinforcement layer (2), a first barrier layer (3) of anti-adhesion material covering at least a part of a surface of the reinforcement layer, and a second barrier layer of anti-adhesion material covering a remaining part of the surface of the reinforcement layer, the second barrier layer being formed of one or more flap member(s) (4).

公开(公告)号：US10549015B2

公开(公告)日：2020-02-04

申请号：US15503758

申请日：2015-09-23

Applicant: Sofradim Production

Inventor： Nicolas Prost ,  Delphine Petit ,  Xavier Bourges

IPC: A61L31/04 ,  A61L31/10 ,  A61F2/00 ,  A61L27/34 ,  A61L27/58 ,  A61L31/14 ,  C08J5/18 ,  C08J7/04 ,  B29C41/12 ,  B29C41/22 ,  B29C41/24 ,  B29C41/02

Abstract: The present invention relates to a method for preparing a surgical anti-adhesion barrier film comprising the following steps: a°) a first solution, comprising an oxidized collagen is prepared, b) a polyphosphate compound is added to the solution of a) in a quantity so as to obtain a concentration of polyphosphate ranging from 0.007 to 0.7 %, by weight, with respect to the total weight of the solution, c) the pH of the solution obtained in b) is adjusted to about 9 by addition of a base or to about 5.1 by addition of an acid, d) a diluted solution is prepared by adding water to solution of c), e) a first layer of solution obtained in c) is casted on an inert support, f) before complete gelation of the layer obtained in d), a second layer, of diluted solution obtained in d) is applied on top of said first layer and let to gelify, g) the gelified first and second layers are dried to obtain a film. The invention further relates to a film obtainable by such a method and to a surgical implant comprising a prosthetic fabric and such a film.

公开(公告)号：US20180243067A1

公开(公告)日：2018-08-30

申请号：US15963388

申请日：2018-04-26

Applicant: Sofradim Production

Inventor： Sébastien Ladet ,  Sebastien Francois ,  Nicolas Prost

IPC: A61F2/00

Abstract: Prosthesis (1) comprising a patch (2) made of biocompatible material, said patch having a generally plane geometric shape that defines two opposite faces, a centre, a length and a width of said patch, characterized in that said patch is provided, on one (2a) of its faces, with a single marking means (3) designed to indicate both the centre (C) of the patch and also the longitudinal direction of said patch.

公开(公告)号：US20170209251A1

公开(公告)日：2017-07-27

申请号：US15384435

申请日：2016-12-20

Applicant: Sofradim Production

Inventor： Sebastien Francois ,  Michel Therin ,  Nicolas Prost

IPC: A61F2/00

CPC classification number: A61F2/0063 ,  A61F2002/0068 ,  A61F2002/009 ,  A61F2210/0076 ,  A61F2220/0058 ,  A61F2230/0019 ,  A61F2240/00 ,  A61F2250/0051

Abstract: The present invention relates to a prosthesis (1) for hernia repair comprising a reinforcement layer (2), a first barrier layer (3) of anti-adhesion material covering at least a part of a surface of the reinforcement layer, and a second barrier layer of anti-adhesion material covering a remaining part of the surface of the reinforcement layer, the second barrier layer being formed of one or more flap member(s) (4).