公开(公告)号：US20060247234A1

公开(公告)日：2006-11-02

申请号：US11412014

申请日：2006-04-26

申请人： Arwinder Nagi ,  Ramarao Chatlapalli ,  Shamim Hasan ,  Rolland Carson ,  Mohamed Ghorab

发明人： Arwinder Nagi ,  Ramarao Chatlapalli ,  Shamim Hasan ,  Rolland Carson ,  Mohamed Ghorab

IPC分类号： A61K31/536 ,  A61K9/48

CPC分类号： A61K31/575 ,  A61K9/145 ,  A61K9/1641 ,  A61K9/1652 ,  A61K9/4858 ,  A61K9/4866 ,  A61K31/536 ,  A61K45/00 ,  A61K45/06

摘要： Compositions, preferably pharmaceutical compositions, containing micronized tanaproget, or pharmaceutically acceptable salt thereof, microcrystalline cellulose, croscarmellose sodium, sodium lauryl sulfate, butylated hydroxyanisole, povidone, and magnesium stearate, are provided. The compositions are useful in contraception and hormone replacement therapy and in the treatment and/or prevention of uterine myometrial fibroids, benign prostatic hypertrophy, benign and malignant neoplastic disease, dysfunctional bleeding, uterine leiomyomata, endometriosis, polycystic ovary syndrome, and carcinomas and adenocarcinomas of the pituitary, endometrium, kidney, ovary, breast, colon, and prostate and other hormone-dependent tumors, and in the preparation of medicaments useful therefor. Additional uses include stimulation of food intake.