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32 条记录 (耗时 0.03 秒)

    MULTIPARTICULATE 5-HTP COMPOSITIONS AND RELATED METHODS
    22.
    发明申请
    MULTIPARTICULATE 5-HTP COMPOSITIONS AND RELATED METHODS 审中-公开
    多重5-HTP组合物及相关方法

    公开(公告)号：US20120315337A1

    公开(公告)日：2012-12-13

    申请号：US13490144

    申请日：2012-06-06

    申请人： Syed Shah ,  Noreen Hassan

    发明人： Syed Shah ,  Noreen Hassan

    IPC分类号： A61K31/405 ,  B05D7/00 ,  A61K9/16

    CPC分类号： A61K9/5073 ,  A61K9/5026 ,  A61K9/5047 ,  A61K31/4045 ,  A61K31/405

    摘要： Enteric coated multiparticulate compositions that use 5-HTP as an active ingredient are disclosed. The multiparticulates have a spheroidal core comprising 5-HTP, microcrystalline cellulose, and hydroxypropyl methylcellulose; a sub-coat comprising hydroxypropyl methylcellulose on the spheroidal core; and an enteric coat on the sub-coated spheroidal core. The average diameter of the particulates is about 0.1-3 mm. Other aspects of the invention include methods of making and methods of using the multiparticulate compositions.

    摘要翻译： 公开了使用5-HTP作为活性成分的肠溶衣多颗粒组合物。 多颗粒具有包含5-HTP，微晶纤维素和羟丙基甲基纤维素的球状核; 在球状核上包含羟丙基甲基纤维素的底涂层; 并在亚涂层球状核上涂上肠衣。 颗粒的平均直径约为0.1-3mm。 本发明的其它方面包括制备方法和使用多微粒组合物的方法。

    Power generation system and method
    25.
    发明授权
    Power generation system and method 有权

    公开(公告)号：US12025107B1

    公开(公告)日：2024-07-02

    申请号：US18496853

    申请日：2023-10-28

    申请人： Syed Shah

    发明人： Syed Shah

    IPC分类号： F03G3/00 ,  F03G7/10

    CPC分类号： F03G3/094 ,  F03G3/097 ,  F03G7/115 ,  F05B2220/70646

    摘要： A system to generate power, the system comprising a shaft configured for one-directional rotation around a horizontal axis, an inertial object coupled to the shaft where the inertial object has an uneven distribution of mass around the shaft, an electric generator configured to extract rotational kinetic energy from the shaft, and an electric motor configured to provide restorative energy to the shaft. The power generation method comprises steps of providing a power generation system, placing the shaft in an initial position, and inducing shaft rotation. Once shaft rotation is induced, the method alternates between steps of power generation and power consumption. More power is generated than consumed, resulting in a surplus of power supplied to the grid.

    Dry powder compound formulations and uses thereof
    26.
    发明申请
    Dry powder compound formulations and uses thereof 审中-公开
    干粉复合制剂及其用途

    公开(公告)号：US20080064743A1

    公开(公告)日：2008-03-13

    申请号：US11899724

    申请日：2007-09-07

    申请人： Syed Shah ,  Christian Ofslager

    发明人： Syed Shah ,  Christian Ofslager

    IPC分类号： A61K31/343 ,  A61P43/00

    CPC分类号： A61K31/485 ,  A61K9/0019 ,  A61K9/19 ,  A61K47/26

    摘要： The present invention provides lyophilized formulations comprising methylnaltrexone, and processes for preparation of provided formulations. Additionally provided are compositions and products containing the methylnaltrexone formulation, as well as methods for producing formulations, compositions and products. Provided formulations as well as compositions and products containing methylnaltrexone formulations are useful for preventing, treating delaying, diminishing or reducing the severity and/or incidence of side effects resulting from administration of analgesic opioids.

    摘要翻译： 本发明提供了包含甲基纳曲酮的冻干制剂，以及制备所提供的制剂的方法。 另外提供了含有甲基纳曲酮制剂的组合物和产品，以及用于制备制剂，组合物和产品的方法。 提供的制剂以及含有甲基纳曲酮制剂的组合物和产品可用于预防，治疗延迟，减少或降低由施用镇痛阿片样物质引起的副作用的严重性和/或发生率。

    Topical formulations containing O-Desmethyl Venlafaxine (ODV) or its salts
    28.
    发明申请
    Topical formulations containing O-Desmethyl Venlafaxine (ODV) or its salts 审中-公开
    含有O-去甲基文拉法辛（ODV）或其盐的局部制剂

    公开(公告)号：US20070054964A1

    公开(公告)日：2007-03-08

    申请号：US11515702

    申请日：2006-09-05

    申请人： Rao Tatapudy ,  Syed Shah

    发明人： Rao Tatapudy ,  Syed Shah

    IPC分类号： A61K31/138

    CPC分类号： A61K9/0014 ,  A61K31/135 ,  A61K31/138

    摘要： The present invention provides topical compositions comprising O-desmethylvenlafaxine (ODV), a selective serotonin and norepinephrine re-uptake inhibitor, or a pharmaceutically acceptable salt thereof. In certain embodiments, the inventive topical formulations contain one or more percutaneous/permucosal absorption enhancers. Also provided are methods of preparing and using these compositions for the treatment of diseases or conditions where a localized therapeutic effect is sought, such as vasomotor symptoms and pain.

    摘要翻译： 本发明提供了包含O-去甲基文拉法辛（ODV），选择性5-羟色胺和去甲肾上腺素再摄取抑制剂或其药学上可接受的盐的局部组合物。 在某些实施方案中，本发明的局部制剂含有一种或多种经皮/粘膜吸收增强剂。 还提供了制备和使用这些组合物用于治疗需要局部治疗效果的疾病或病症如血管舒缩症状和疼痛的方法。