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公开(公告)号：US09790201B2
公开(公告)日：2017-10-17
申请号：US14910377
申请日：2014-08-07
Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
Inventor： Sarah Bousba , Anne Goldby , Kerry Jenkins , Natasha Kinsella , Martin Teall
IPC: A61K31/4439 , A61K31/444 , A61K31/55 , C07D401/06 , C07D403/06 , A61K31/454 , A61K31/4545 , A61K31/501 , C07D401/14
CPC classification number: C07D401/06 , A61K31/454 , A61K31/4545 , A61K31/501 , A61K31/55 , C07D401/14 , C07D403/06
Abstract: The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof (Formula (I)) in which m, X, R1, R2, R3 and R5 are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.
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22.发明申请SULFONYL PIPERIDINE DERIVATIVES AND THEIR USE FOR TREATING PROKINETICIN MEDIATED DISEASES 审中-公开磺酰哌啶衍生物及其用于治疗原代介导性疾病的用途公开(公告)号：US20160376256A1
公开(公告)日：2016-12-29
申请号：US15262436
申请日：2016-09-12
Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
Inventor： Colm Carroll , Anne Goldby , Martin Teall
IPC: C07D401/12 , C07D401/14 , A61K31/4545 , A61K31/454
CPC classification number: C07D401/12 , A61K31/454 , A61K31/4545 , A61K45/06 , C07D211/96 , C07D401/14
Abstract: The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof in which q, R11, R12, R13 and R14 are as defined in the specification, for use in therapy.
Abstract translation: 其中q，R11，R12，R13和R14如说明书中所定义，用于治疗。
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23.发明授权Sulfonyl piperidine derivatives and their use for treating prokineticin mediated diseases 有权磺酰哌啶衍生物及其用于治疗促动动因素介导的疾病的用途公开(公告)号：US09475795B2
公开(公告)日：2016-10-25
申请号：US14402751
申请日：2013-05-29
Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
Inventor： Colm Carroll , Anne Goldby , Martin Teall
IPC: C07D401/12 , C07D401/14 , A61K31/454 , A61K31/4545 , A61K45/06 , C07D211/96
CPC classification number: C07D401/12 , A61K31/454 , A61K31/4545 , A61K45/06 , C07D211/96 , C07D401/14
Abstract: The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof: (I) in which m, n, W, X, Y, Z, R1, R2, R3 and R4 are as defined in the specification, for use in the treatment or prevention of a diseases o conition mediated by a prokineticin, such as psychiatric and neurological conditions.
Abstract translation: 本发明提供式（I）化合物及其药学上可接受的盐：（I）其中m，n，w，X，Y，Z，R 1，R 2，R 3和R 4如本说明书中所定义， 治疗或预防由促运动素介导的疾病，如精神病学和神经病学疾病。
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24.发明申请1-SULFONYL PIPERIDINE DERIVATIVES AS MODULATORS OF PROKINETICIN RECEPTORS 审中-公开作为孕激素受体调节剂的1-磺基哌啶衍生物公开(公告)号：US20160122317A1
公开(公告)日：2016-05-05
申请号：US14893148
申请日：2014-06-20
Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
Inventor： Martin Teall
IPC: C07D401/12 , A61K31/454
CPC classification number: C07D401/12 , A61K31/454
Abstract: The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof in which m, n, W, X, Y, Z, R1, R2, R3, R4 and R5 are as defined in the specification, compositions containing them and their use in therapy.
Abstract translation: 本发明提供式（I）化合物及其药学上可接受的盐，其中m，n，W，X，Y，Z，R 1，R 2，R 3，R 4和R 5如本说明书中所定义，含有它们的组合物及其 用于治疗。
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