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公开(公告)号：US20210147841A1
公开(公告)日：2021-05-20
申请号：US17089284
申请日：2020-11-04
Applicant: The Regents of the University of California
Inventor： Alexander Marson , Jeffrey A. Bluestone , Kathrin Schumann
IPC: C12N15/113 , C12N9/22 , C12N5/0783
Abstract: The disclosure features methods directed to modifying regulatory T (Treg) cell stability by inhibiting the expression of one or more transcription factors and/or inhibiting one or more genes or gene products regulated by the transcription factors. The disclosure also features compositions comprising the Treg cells having modified stability.
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