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21.发明授权N, n'-bis(trifluoroacetyl)actinospectacin and the 9-trifluoroacetyl thereof 失效N，N'-双（三氟乙酰基）荧光亮氨酸及其9-三氟乙酰基
公开(公告)号：US3184478A
公开(公告)日：1965-05-18
申请号：US18495462
申请日：1962-04-04
Applicant: UPJOHN CO
Inventor： BIRKENMEYER ROBERT D , HERMAN HOEKSEMA
IPC: C07D493/04
CPC classification number: A61K31/70 , C07D493/04
Abstract: N, N1-bis (trifluoroacetyl) actinospectacin and N, N1-bis (trifluoroacetyl) actinospectacin 9-trifluoroacetate may be prepared by reacting actinospectacin with two or three moles respectively of trifluoroacetic anhydride or a trifluoroacetyl halide in the presence of an acid acceptor such as pyridine or a tertiary amine. Specification 959,675 is referred to.ALSO:The compounds N,N1-bis (trifluoroacetyl) actinospectacin 9-trifluoroacetate (see Division C2) may be used (a) to prevent or minimize liquefaction in packed yeast caused by Proteus vulgaris or (b) for treating breeding places of silkworms to prevent or minimize infections 959,675 is referred to.ALSO:The compounds N, N1-bis (trifluoroacetyl) actinospectacin and N, N1-bis (trifluoroacetyl) actinospectacin 9-trifluoroacetate (see Division C2) may be used to prevent the formation of slime in papermill systems caused by the organism Escherichia coli. Specification 959,675 is referred to.
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22.发明授权Process for the preparation of 16alpha-hydroxylated steroids and novel intermediates 失效制备16α-羟基化类固醇和新型中间体的方法
公开(公告)号：US3068251A
公开(公告)日：1962-12-11
申请号：US142360
申请日：1960-01-11
Applicant: UPJOHN CO
Inventor： MAGERLEIN BARNEY J , BIRKENMEYER ROBERT D , FRED KAGAN
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公开(公告)号：US2995576A
公开(公告)日：1961-08-08
申请号：US81673459
申请日：1959-05-29
Applicant: UPJOHN CO
Inventor： FRED KAGAN , BIRKENMEYER ROBERT D
IPC: C07F9/655
CPC classification number: C07F9/65515
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公开(公告)号：US2865951A
公开(公告)日：1958-12-23
申请号：US43205454
申请日：1954-05-24
Applicant: UPJOHN CO
Inventor： BIRKENMEYER ROBERT D , HEINZELMAN RICHARD V
CPC classification number: C08G18/10
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公开(公告)号：US2827489A
公开(公告)日：1958-03-18
申请号：US56195156
申请日：1956-01-27
Applicant: UPJOHN CO
Inventor： BIRKENMEYER ROBERT D , SPEETER MERRILL E
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Patent Agency Ranking
公开(公告)号：US3549615A
公开(公告)日：1970-12-22
申请号：US3549615D
申请日：1968-10-17
Applicant: UPJOHN CO
Inventor： BIRKENMEYER ROBERT D
CPC classification number: C07H15/16 , Y02P20/55 , Y10S516/07
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公开(公告)号：US3496163A
公开(公告)日：1970-02-17
申请号：US3496163D
申请日：1968-01-09
Applicant: UPJOHN CO
Inventor： BIRKENMEYER ROBERT D , KAGAN FRED
CPC classification number: C07D207/22 , C07H15/16 , C12P19/64 , Y10S516/06
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公开(公告)号：US3475407A
公开(公告)日：1969-10-28
申请号：US3475407D
申请日：1967-12-22
Applicant: UPJOHN CO
Inventor： BIRKENMEYER ROBERT D
CPC classification number: C07H15/16
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29.发明授权7-deoxylincomycin and analogs and isomers thereof and process for making the same 失效7-去氧吗啉蛋白及其类似物及其制备方法及其制备方法
公开(公告)号：US3435025A
公开(公告)日：1969-03-25
申请号：US3435025D
申请日：1966-03-18
Applicant: UPJOHN CO
Inventor： BIRKENMEYER ROBERT D
CPC classification number: C07H15/16 , Y10S516/06
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公开(公告)号：US3282957A
公开(公告)日：1966-11-01
申请号：US35948764
申请日：1964-04-13
Applicant: UPJOHN CO
Inventor： MAGERLEIN BARNEY J , BIRKENMEYER ROBERT D
IPC: C07D207/16
CPC classification number: C07D207/16 , Y10S514/944
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