公开(公告)号：US20120295268A1

公开(公告)日：2012-11-22

申请号：US13473010

申请日：2012-05-16

Applicant: Alan Furlan

Inventor： Alan Furlan

IPC: C12M1/34 ,  G01N21/64

CPC classification number: G01N21/6428 ,  C12Q1/686 ,  G01N21/253 ,  G01N21/255 ,  G01N21/645 ,  G01N21/6486 ,  G01N2021/6441 ,  G01N2021/6471 ,  G01N2201/0423 ,  G01N2201/0668 ,  G02B7/006

Abstract: The present disclosure provides instruments and methods for detecting an analyte which are capable of exciting a plurality of luminescence labels and detecting light emitted therefrom. The instrument includes a filter carrier adapted for carrying a plurality of filter portion pairs, each pair related to a luminescence label and comprising a first filter portion for transmitting excitation light, and a second filter portion for transmitting emitted light. The first filter portion of a pair comprises a second filter portion of another pair. Also, the filter portions are arranged such that a pair can be brought into an operative condition whereby a first filter portion is in the excitation beam path and a second filter portion is in the emission beam path. The filter carrier and beam paths may be moved with respect to each other by a moving mechanism so as to bring a pair into operative condition.

Abstract translation: 本公开提供了用于检测能够激发多个发光标签并检测从其发射的光的分析物的仪器和方法。 仪器包括适于承载多个过滤器部分对的过滤器载体，每一对与发光标签相关，并且包括用于传递激发光的第一过滤器部分和用于传输发射光的第二过滤器部分。 一对的第一过滤器部分包括另一对的第二过滤器部分。 此外，滤光器部分被布置成使得一对可以进入操作状态，由此第一滤光器部分处于激发光束路径中，并且第二滤光器部分处于发射光束路径中。 过滤器载体和梁路径可以通过移动机构相对于彼此移动，以使一对成为操作状态。

公开(公告)号：USRE31150E

公开(公告)日：1983-02-15

申请号：US296780

申请日：1981-08-27

Applicant: Guenter Ginsberg ,  Thomas Horne ,  Robert L. Kreiselman

Inventor： Guenter Ginsberg ,  Thomas Horne ,  Robert L. Kreiselman

IPC: G01N21/25

CPC classification number: G01N21/253 ,  G01N2201/0423

Abstract: Apparatus for measuring progressively the absorbance changes of a large number of aliquots from a plurality of different samples. The sample introduction, testing instructions, aliquot preparation, reagent dispensing, absorbance measuring and data recording all can be accomplished in a continuous mode of processing. Stat and batch operation also can be accomplished. The aliquots are in an array of cuvettes which is advanced slowly along a circular path. Photometer means, preferably having several photometric detectors, are mounted in fixed orientation on a common support that advances rapidly along a similar circular path, such that radiation passing through each of the cuvettes is monitored many times by a specific photometric detector by the time that cuvette completes one circuit of its path. The photometric detectors can operate at several different wavelengths. Many different chemical reactions can be monitored at the same time. The radiant energy passing through each cuvette is received by the continuously moving photometer means, is converted electrically into a digitized value proportional to absorbance and is transmitted digitally from the moving assemblage of photometric detectors, cuvettes and electrical components to a stationary receiver. In one embodiment, the digital transmission is in the form of a pulsed train of light signals. In another embodiment, one or more slip rings transmit electric signals from the moving assemblage to the stationary portion. Suitable drive elements, sample and reagent storage and transfer mechanisms as well as cuvette laundry means may be provided as part of the complete apparatus.