公开(公告)号：US20220112303A1

公开(公告)日：2022-04-14

申请号：US17560582

申请日：2021-12-23

Applicant: Ichilov Tech Ltd.

Inventor： Nadir ARBER ,  Shiran SHAPIRA ,  Diana KAZANOV

IPC: C07K16/28 ,  A61P35/00

Abstract: An anti-CD24 antibody is provided. Accordingly, there is provided an antibody comprising an antigen recognition domain which specifically binds CD24 and comprises complementarity determining regions (CDRs) as set forth in SEQ ID NOs: 2, 3 and 4 arranged in a sequential order from N to C on a light chain of the antibody and CDRs as set forth in SEQ ID NOs: 6, 7 and 8 arranged in a sequential order from N to C on a heavy chain of said antibody. Also provided are polynucleotides encoding the antibody, host cells expressing the antibody the uses thereof.