公开(公告)号：US20170163538A1

公开(公告)日：2017-06-08

申请号：US14972062

申请日：2015-12-16

Applicant: Macau University of Science and Technology

Inventor： Li Feng ,  Liang Zhou ,  Zhijun Xu ,  Yujun Zhang

IPC: H04L12/803 ,  H04L12/851 ,  H04L12/707 ,  H04L29/06

CPC classification number: H04L47/125 ,  H04L45/24 ,  H04L47/2483 ,  H04L69/22

Abstract: Compute-intensive packet processing (CIPP) in a computer system comprising a programmable computing platform is accelerated by using a packet I/O engine, implemented on the platform, to perform packet I/O functions, where the packet I/O engine is configured to achieve direct access to a network interface card (NIC) from a user application. For a Linux-based computer system, standard I/O mechanisms of Linux are bypassed and only the packet I/O engine is used in performing the I/O functions. Furthermore, the computer system is configured to: process a batch of packets, instead of packet by packet, in every function call; and when moving a packet between a buffer of an individual user application and a queue of the packet I/O engine, copy a packet descriptor of the packet instead the entire packet. In addition, workflows across different working threads are balanced and parallelism is exploited to fully utilize resources of the platform.

公开(公告)号：US20170095443A1

公开(公告)日：2017-04-06

申请号：US14872198

申请日：2015-10-01

Applicant: Macau University of Science and Technology

Inventor： Pei Luo

IPC: A61K31/357 ,  A61K36/28 ,  A61K31/216

CPC classification number: A61K31/357 ,  A61K31/216 ,  A61K36/28 ,  A61K2300/00

Abstract: A caffeoylquinic acid-rich extract obtained from Erigeron multiradiatus and a method for producing the same. A caffeoylquinic acid-rich extract includes at least 15% by weight of a mixture of certain caffeoylquinic acids. The extract with the mixture of caffeoylquinic acids is highly efficacious in treating and preventing myocardial ischemia or myocardial ischemia reperfusion injuries. A method for treating or preventing a disease caused by myocardial ischemia or myocardial ischemia reperfusion includes administering a therapeutically effective amount of the caffeoylquinic acid-rich extract to a subject. Pharmaceutical compositions including the caffeoylquinic acid-rich extract are also disclosed.

公开(公告)号：US20170083010A1

公开(公告)日：2017-03-23

申请号：US14918564

申请日：2015-10-21

Applicant: Macau University of Science and Technology

Inventor： Naiqi Wu ,  Qinghua Zhu ,  Mengchu Zhou ,  Yan Qiao

IPC: G05B19/418

CPC classification number: G05B19/41865 ,  G05B2219/34418 ,  G05B2219/45031 ,  G05B2219/50391 ,  Y10S901/02 ,  Y10S901/30

Abstract: Recent trends of larger wafer and smaller lot sizes bring cluster tools with frequent lot switches. Practitioners must deal with more transient processes during such switches, including start-up and close-down processes. To obtain higher yield, it is necessary to shorten the duration of transient processes. Much prior effort was poured into the modeling and scheduling for the steady state of cluster tools. In the existing literature, no attention has been turned to optimize the close-down process for single-arm cluster tools with wafer residency constraints. This invention intends to do so by 1) developing a Petri net model to analyze their scheduling properties and 2) proposing Petri net-based methods to solve their close-down optimal scheduling problems under different workloads among their process steps. Industrial examples are used to illustrate the effectiveness and application of the proposed methods.

公开(公告)号：US20170056390A1

公开(公告)日：2017-03-02

申请号：US14925962

申请日：2015-10-28

Applicant: Macau University of Science and Technology

Inventor： Kam Wai WONG ,  Yuen Kwan LAW ,  Liang LIU

IPC: A61K31/4745

CPC classification number: A61K31/4745

Abstract: The present invention discloses a method of treating cancer and/or multidrug-resistant cancer, comprising administering an effective amount of hernandezine or thalidezine. A pharmaceutical composition comprising hernandezine or thalidezine admixed with a pharmaceutical carrier for treating cancers and/or multidrug-resistant cancer is also disclosed.

Abstract translation: 本发明公开了一种治疗癌症和/或多药耐药性癌症的方法，其包括施用有效量的涕灭威或沙利度胺。 还公开了包含与用于治疗癌症和/或多药耐药性癌症的药物载体混合的栀子苷或沙利度胺的药物组合物。

公开(公告)号：US20170019933A1

公开(公告)日：2017-01-19

申请号：US14828159

申请日：2015-08-17

Applicant: Macau University of Science and Technology

Inventor： Qinglin Zhao ,  Fangxin Xu ,  Yu Zeng ,  Jie Yang

IPC: H04W74/08 ,  H04W72/14

CPC classification number: H04W74/0866 ,  H04W74/008 ,  H04W74/02 ,  H04W74/08 ,  H04W74/0816

Abstract: A MAC protocol, useful for wireless local area networks (WLANs), is provided for improving throughput efficiency. The protocol includes three concurrent processes, and the channel is divided into a contention subchannel and a transmission subchannel. In the contention process, all nodes use the standard RTS/CTS mechanism operated on the contention channel to contend for a right of transmission. When one node gains the right, all the nodes store the contention result into their respective contention queue (CQ) buffers. In the transmission process, the nodes sequentially transmit their data over the transmission channel according to the order of the nodes stored in the CQ buffers. When one node finishes data transmission, the CQ buffers are updated. The contention process and the transmission process are connected by the queuing process, where each node dynamically updates its own CQ buffer according to the contention result and each instance of data transmission.

Abstract translation: 提供了一种用于无线局域网（WLAN）的MAC协议，用于提高吞吐量效率。 该协议包括三个并发进程，并且该信道被划分为竞争子信道和传输子信道。 在竞争过程中，所有节点都使用在争用通道上运行的标准RTS / CTS机制来争取传输权。 当一个节点获得权限时，所有节点将争用结果存储到它们各自的争用队列（CQ）缓冲器中。 在传输过程中，节点根据存储在CQ缓冲器中的节点的顺序，依次通过传输信道发送它们的数据。 当一个节点完成数据传输时，更新CQ缓冲区。 竞争过程和传输过程通过排队过程连接，其中每个节点根据竞争结果和每个数据传输实例动态更新自己的CQ缓冲区。

公开(公告)号：US20170019922A1

公开(公告)日：2017-01-19

申请号：US15153748

申请日：2016-05-13

Applicant: Macau University of Science and Technology

Inventor： Qinglin ZHAO ,  Fangxin XU ,  Yu ZENG ,  Jie YANG

IPC: H04W74/08 ,  H04W74/00 ,  H04W72/14

CPC classification number: H04W74/0866 ,  H04W74/008 ,  H04W74/02 ,  H04W74/08 ,  H04W74/0816

Abstract: A MAC protocol, useful for WLANs, is provided for random access over a channel. The protocol includes three concurrent processes. The channel includes a contention subchannel and a transmission subchannel. In the contention process, all nodes use the standard RTS/CTS mechanism operated on the contention subchannel to contend for a transmission right. When one node gains the right, all the nodes store the contention result into their respective contention queue (CQ) buffers. In the transmission process, the nodes sequentially transmit their data over the transmission subchannel according to the order of the nodes stored in the CQ buffers. When one node finishes transmission, the CQ buffers are updated. The contention and transmission processes are connected by the queuing process for dynamically updating each node's CQ buffer. When OFDM is used in a random-access system, numbers of data subcarriers in both subchannels for maximizing the system throughput are given.

Abstract translation: 提供对WLAN有用的MAC协议，用于通过信道进行随机访问。 协议包括三个并发进程。 信道包括争用子信道和传输子信道。 在争用过程中，所有节点都使用在争用子信道上运行的标准RTS / CTS机制来争取发送权。 当一个节点获得权限时，所有节点将争用结果存储到它们各自的争用队列（CQ）缓冲器中。 在传输过程中，节点根据存储在CQ缓冲器中的节点的顺序，依次通过传输子信道发送它们的数据。 当一个节点完成传输时，更新CQ缓冲区。 争用和传输过程通过排队过程连接，动态更新每个节点的CQ缓冲区。 当在随机接入系统中使用OFDM时，给出用于最大化系统吞吐量的两个子信道中的数据子载波的数目。

公开(公告)号：US09526722B1

公开(公告)日：2016-12-27

申请号：US14744042

申请日：2015-06-19

Applicant: Macau University of Science and Technology

Inventor： Xiao Jun Yao ,  Lai Han Leung ,  Lian Xiang Luo ,  Yan Ling Zhou ,  Liang Liu

IPC: A01N43/42 ,  A61K31/444 ,  A61K31/4745

CPC classification number: A61K31/4745

Abstract: The present invention provides a compound that inhibits activity of oncogenic ROS1, a composition comprising said compound. The present invention also provides the use of said composition for treating cancer.

Abstract translation: 本发明提供抑制致癌ROS1活性的化合物，其是包含所述化合物的组合物。 本发明还提供了所述组合物用于治疗癌症的用途。

公开(公告)号：US09333645B1

公开(公告)日：2016-05-10

申请号：US14639960

申请日：2015-03-05

Applicant: Macau University of Science and Technology

Inventor： Naiqi Wu ,  Mengchu Zhou ,  Chunrong Pan ,  Yan Qiao

IPC: G05D3/12 ,  B25J9/00 ,  G05B19/418 ,  G06F17/50

CPC classification number: B25J9/0087 ,  G05B19/41865 ,  G05B2219/32245 ,  G05B2219/45031 ,  G06F17/5013 ,  H01L21/67742 ,  Y02P90/20 ,  Y10S901/02 ,  Y10S901/41

Abstract: A method for scheduling dual-armed cluster tools with wafer revisiting is provided. In order to speed up start-up transient processes, the present invention adopts a program evaluation and review technique for the analysis of start-up transient processes and develops optimization algorithms for their scheduling for dual-arm cluster tools. Then, their complexity is analyzed.

Abstract translation: 提供了一种使用晶片重新访问来调度双机群集工具的方法。 为了加快启动瞬态过程，本发明采用程序评估和审查技术对启动瞬态过程进行分析，并开发了用于双臂集群工具调度的优化算法。 然后分析其复杂性。

公开(公告)号：US20160037757A1

公开(公告)日：2016-02-11

申请号：US14620141

申请日：2015-02-11

Applicant: Macau University of Science and Technology

Inventor： Liang LIU ,  Ting LI ,  Kam Wai WONG ,  Zhihong JIANG ,  Hua ZHOU

IPC: A01K67/027 ,  A61K49/00

CPC classification number: A01K67/0278 ,  A01K2207/12 ,  A01K2227/105 ,  A01K2267/01 ,  A01K2267/0368 ,  A61K49/0008 ,  G01N33/573 ,  G01N33/574 ,  G01N2333/91215 ,  G01N2800/102 ,  G01N2800/44

Abstract: The present invention provides an in vivo platform for identifying and determining therapeutic or prophylactic activity of test compounds in delay-type hypersensitivity (DTH) and other inflammatory or cancerous diseases mediated by activation of IKK-βC46A mutants. The in vivo platform of the present invention is a non-human transgenic mammal, e.g., a mouse model, with a site directed mutagenesis at a cysteine residue replaced by alanine in IKK-β protein kinase. The site directed mutagenesis is introduced by a specially designed targeting vector containing a transversion in exon 3 of the Ikbkb genes encoding the IKK-β. The present invention also provides methods for generating the transgenic mammal and for determining and identifying compounds that can inhibit activation of IKK-βC46A mutants.

Abstract translation: 本发明提供了一种用于鉴定和确定延迟型超敏反应（DTH）和通过IKK-和bgr C46A突变体的活化介导的其它炎性或癌性疾病的测试化合物的治疗或预防活性的体内平台。 本发明的体内平台是非人转基因哺乳动物，例如小鼠模型，在IKK-和bgr中被半胱氨酸残基替换为丙氨酸的位点定向诱变; 蛋白激酶。 通过特异设计的靶向载体引入定点诱变，所述靶向载体在编码IKK-＆bgr的Ikbkb基因的外显子3中含有颠换。 本发明还提供了产生转基因哺乳动物以及用于测定和鉴定可以抑制IKK-Bgr C46A突变体活化的化合物的方法。

公开(公告)号：US09232351B1

公开(公告)日：2016-01-05

申请号：US14658227

申请日：2015-03-15

Applicant: Macau University of Science and Technology

Inventor： Qinglin Zhao

IPC: H04W24/00 ,  H04W4/02 ,  H04W64/00 ,  H04W68/00

CPC classification number: H04W4/02 ,  H04W4/021 ,  H04W60/04 ,  H04W64/003 ,  H04W68/005

Abstract: The present invention provides a method for updating a mobile terminal (MT) for a mobile communication network when the MT crosses a boundary of a first location-update (LA) area. The method comprises determining a second LA to be assigned to the MT for replacing the first LA. The second LA is characterized by a LA center and a LA size, both determined by optimizing them in a sense that a mean total location-management cost is minimized without restricting the LA center to be fixed at the initial position. The initial position is defined as the location where the MT performs a latest location update at the first LA before crossing the boundary. This invention also provides schemes of partitioning the second LA into sub-paging areas for use in paging the MT when a call arrives at the network, so as to minimize the paging cost while satisfying delay requirements.

Abstract translation: 本发明提供一种当MT越过第一位置更新（LA）区域的边界时，为移动通信网络更新移动终端（MT）的方法。 该方法包括确定要分配给MT以用于替换第一LA的第二LA。 第二个LA的特征在于LA中心和LA大小，两者都通过优化它们来确定，即在平均总位置管理成本最小化的意义上，而不将LA中心限制在初始位置。 初始位置被定义为MT在穿过边界之前在第一LA处执行最新位置更新的位置。 本发明还提供了当呼叫到达网络时将第二LA划分为子寻呼区域以用于寻呼MT的方案，以便在满足延迟要求的同时最小化寻呼成本。