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31.发明授权Apparatus for treating venous insufficiency using directionally applied energy 失效使用定向施加能量治疗静脉功能不全的装置公开(公告)号：US06981972B1
公开(公告)日：2006-01-03
申请号：US09483969
申请日：2000-01-18
IPC分类号： A61B17/38
CPC分类号： A61B18/1492 , A61B17/00008 , A61B2017/22051 , A61B2017/22097 , A61B2018/00011 , A61B2018/00029 , A61B2018/00083 , A61B2018/00154 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00285 , A61B2018/00404 , A61B2018/00488 , A61B2018/00702 , A61B2018/00744 , A61B2018/00755 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00875 , A61B2018/1253 , A61B2018/126 , A61B2018/1465 , A61B2018/1497
摘要： A catheter introduces electrodes in a vein for a minimally invasive treatment of venous insufficiency by the application of energy to cause selective heating of the vein. The catheter is positioned within the vein to be treated, and the electrodes on the catheter are moved toward one side of the vein. RF energy is applied in a directional manner from the electrodes at the working end of the catheter to cause localized heating and corresponding shrinkage of the adjacent venous tissue, which may include commissures, leaflets and ostia. Fluoroscopy or ultrasound may be used to detect shrinkage of the vein. After treating one section of the vein, the catheter can be repositioned to place the electrodes to treat different sections of the vein until all desired venous valves are repaired and rendered functionally competent.
摘要翻译： 导管通过施加能量来引起静脉的选择性加热，将电极引入静脉中用于微创治疗静脉功能不全。 将导管定位在待治疗的静脉内，导管上的电极向静脉的一侧移动。 射频能量以定向方式从导管的工作端处的电极施加，以引起相邻静脉组织的局部加热和相应的收缩，其可以包括连合，小叶和口。 荧光透视或超声可用于检测静脉的收缩。 在治疗静脉的一部分之后，可以重新定位导管以放置电极来治疗静脉的不同部分，直到所有期望的静脉瓣被修复并且具有功能上的能力。
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公开(公告)号：US06263248B1
公开(公告)日：2001-07-17
申请号：US09394773
申请日：1999-09-10
IPC分类号： A61F700
CPC分类号： A61B18/1492 , A61B2018/00214 , A61B2018/00404 , A61B2018/00488 , A61B2018/00797 , A61B2018/126
摘要： A catheter having expandable electrodes for applying energy to a vein for a minimally invasive treatment of venous insufficiency, and having expandable stent members for limiting vein shrinkage to a final desired vein diameter. The catheter includes a set of expandable arms that are pre-formed into an outwardly bowed configuration. An electrode is mounted on each arm. When uncovered by sliding a control sleeve proximally, the electrode arms expand outwardly into apposition with the vein wall for applying energy to the vein wall to heat and shrink the vein. The catheter further includes a set of expandable stent arms deployed to the final desired diameter of the vein. The electrode arms and the stent arms are decoupled so that each is separately controllable. In a method, the stent arms are expanded outward to the desired final diameter of the vein. The electrode arms are then expanded into apposition with the vein wall and energy is applied to shrink the vein into contact with the stent arms. The application of energy is ceased at that time.
摘要翻译： 一种导管，其具有用于向静脉施加能量以用于静脉功能不全的微创治疗的可扩张电极，并且具有用于将静脉收缩限制到最终所需静脉直径的可扩张支架构件。 导管包括预先形成为向外弓形构型的一组可扩张臂。 电极安装在每个臂上。 当通过向近侧滑动控制套筒而露出时，电极臂向外扩展成与静脉壁相连，用于向静脉壁施加能量以加热和收缩静脉。 该导管还包括一组可展开的支架臂，其部署到静脉的最终期望直径。 电极臂和支架臂被去耦合，使得每个电极臂和支架臂都是可分离的。 在一种方法中，支架臂向外扩张到所需静脉的最终直径。 然后将电极臂扩大成与静脉壁相配合并施加能量以收缩静脉以与支架臂接触。 那时候，能源的应用就不复存在了。
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33.发明授权Method and apparatus for treating venous insufficiency using directionally applied energy 失效使用定向施加能量治疗静脉功能不全的方法和装置
公开(公告)号：US6033398A
公开(公告)日：2000-03-07
申请号：US811820
申请日：1997-03-04
CPC分类号： A61B18/1492 , A61B17/00008 , A61B2017/22051 , A61B2017/22097 , A61B2018/00011 , A61B2018/00029 , A61B2018/00083 , A61B2018/00154 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00285 , A61B2018/00404 , A61B2018/00488 , A61B2018/00702 , A61B2018/00744 , A61B2018/00755 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00875 , A61B2018/1253 , A61B2018/126 , A61B2018/1465 , A61B2018/1497
摘要： A catheter introduces electrodes in a vein for a minimally invasive treatment of venous insufficiency by the application of energy to cause selective heating of the vein. The catheter is positioned within the vein to be treated, and the electrodes on the catheter are moved toward one side of the vein. RF energy is applied in a directional manner from the electrodes at the working end of the catheter to cause localized heating and corresponding shrinkage of the adjacent venous tissue, which may include commissures, leaflets and ostia. Fluoroscopy or ultrasound may be used to detect shrinkage of the vein. After treating one section of the vein, the catheter can be repositioned to place the electrodes to treat different sections of the vein until all desired venous valves are repaired and rendered functionally competent.
摘要翻译： 导管通过施加能量来引起静脉的选择性加热，将电极引入静脉中用于微创治疗静脉功能不全。 将导管定位在待治疗的静脉内，导管上的电极向静脉的一侧移动。 射频能量以定向方式从导管的工作端处的电极施加，以引起相邻静脉组织的局部加热和相应的收缩，其可以包括连合，小叶和口。 荧光透视或超声可用于检测静脉的收缩。 在治疗静脉的一部分之后，可以重新定位导管以放置电极来治疗静脉的不同部分，直到所有期望的静脉瓣被修复并且具有功能上的能力。
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34.发明申请Apparatus for Treating Venous Insufficiency Using Directionally Applied Energy 有权使用定向应用能量治疗静脉功能不全的装置公开(公告)号：US20110202047A1
公开(公告)日：2011-08-18
申请号：US13095335
申请日：2011-04-27
IPC分类号： A61B18/22
CPC分类号： A61B18/1492 , A61B17/00008 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00404 , A61B2018/1253 , A61B2018/126
摘要： A catheter introduces electrodes in a vein for a minimally invasive treatment of venous insufficiency by the application of energy to cause selective heating of the vein. The catheter is positioned within the vein to be treated, and the electrodes on the catheter are moved toward one side of the vein. RF energy is applied in a directional manner from the electrodes at the working end of the catheter to cause localized heating and corresponding shrinkage of the adjacent venous tissue, which may include commissures, leaflets and ostia. Fluoroscopy or ultrasound may be used to detect shrinkage of the vein. After treating one section of the vein, the catheter can be repositioned to place the electrodes to treat different sections of the vein until all desired venous valves are repaired and rendered functionally competent.
摘要翻译： 导管通过施加能量来引起静脉的选择性加热，将电极引入静脉中用于微创治疗静脉功能不全。 将导管定位在待治疗的静脉内，导管上的电极向静脉的一侧移动。 射频能量以定向方式从导管的工作端处的电极施加，以引起相邻静脉组织的局部加热和相应的收缩，其可以包括连合，小叶和口。 荧光透视或超声可用于检测静脉的收缩。 在治疗静脉的一部分之后，可以重新定位导管以放置电极来治疗静脉的不同部分，直到所有期望的静脉瓣被修复并且具有功能上的能力。
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公开(公告)号：US6014589A
公开(公告)日：2000-01-11
申请号：US968630
申请日：1997-11-12
CPC分类号： A61B18/1492 , A61B2018/00214 , A61B2018/00404 , A61B2018/00488 , A61B2018/00797 , A61B2018/126
摘要： A catheter having expandable electrodes for applying energy to a vein for a minimally invasive treatment of venous insufficiency, and having expandable stent members for limiting vein shrinkage to a final desired vein diameter. The catheter includes a set of expandable arms that are pre-formed into an outwardly bowed configuration. An electrode is mounted on each arm. When uncovered by sliding a control sleeve proximally, the electrode arms expand outwardly into apposition with the vein wall for applying energy to the vein wall to heat and shrink the vein. The catheter further includes a set of expandable stent arms deployed to the final desired diameter of the vein. The electrode arms and the stent arms are decoupled so that each is separately controllable. In a method, the stent arms are expanded outward to the desired final diameter of the vein. The electrode arms are then expanded into apposition with the vein wall and energy is applied to shrink the vein into contact with the stent arms. The application of energy is ceased at that time.
摘要翻译： 一种导管，其具有用于向静脉施加能量以用于静脉功能不全的微创治疗的可扩张电极，并且具有用于将静脉收缩限制到最终所需静脉直径的可扩张支架构件。 导管包括预先形成为向外弓形构型的一组可扩张臂。 电极安装在每个臂上。 当通过向近侧滑动控制套筒而露出时，电极臂向外扩展成与静脉壁相连，用于向静脉壁施加能量以加热和收缩静脉。 该导管还包括一组可展开的支架臂，其部署到静脉的最终期望直径。 电极臂和支架臂被去耦合，使得每个电极臂和支架臂都是可分离的。 在一种方法中，支架臂向外扩张到所需静脉的最终直径。 然后将电极臂扩大成与静脉壁相配合并施加能量以收缩静脉以与支架臂接触。 那时候，能源的应用就不复存在了。
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公开(公告)号：US5181920A
公开(公告)日：1993-01-26
申请号：US624855
申请日：1990-12-10
CPC分类号： A61B17/3207 , A61M2025/1097 , A61M25/104
摘要： An atherectomy device for reducing stenosis material from a vascular vessel is provided. The atherectomy device includes an elongated flexible tubular member having at least one lumen extending therethrough and having proximal and distal extremities. A flexible drive means disposed within the tubular members is free to move both rotationally and axially therein. A cutting assembly is carried by the distal extremity of the flexible tubular member with a cutter being carried by the distal extremity of the flexible drive means for removing a portion of the stenosis from the vessel wall. An inflatable dilation balloon is carried by the tubular member proximally of the cutter for further reducing the stenosis after initial reduction by the cutter. A perfusion channel maintains blood flow past the dilation balloon. Methods of the present invention include cutting and dilating a stenosis, cutting then immediately dilating a stenosis, and dilating then immediately cutting a stenosis.
摘要翻译： 提供了用于从血管容器减少狭窄物质的粥样斑块切除装置。 粥样斑块切除装置包括细长的柔性管状构件，其具有延伸穿过其中并具有近端和远端的至少一个内腔。 设置在管状构件内的柔性驱动装置自由地在其中旋转地和轴向地移动。 切割组件由柔性管状构件的远端承载，切割器由柔性驱动装置的远端承载，用于从血管壁去除一部分狭窄。 可膨胀的膨胀气囊由切割器的近侧的管状构件承载，以进一步减少由切割器初始还原之后的狭窄。 灌注通道保持血液流过扩张气球。 本发明的方法包括切割和扩张狭窄，切割然后立即扩张狭窄，并且立即扩张然后立即切开狭窄。
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37.发明授权Method and apparatus for treating venous insufficiency using directionally applied energy 有权使用定向施加能量治疗静脉功能不全的方法和装置公开(公告)号：US08291915B2
公开(公告)日：2012-10-23
申请号：US13095335
申请日：2011-04-27
IPC分类号： A61B19/00
CPC分类号： A61B18/1492 , A61B17/00008 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00404 , A61B2018/1253 , A61B2018/126
摘要： A catheter introduces electrodes in a vein for a minimally invasive treatment of venous insufficiency by the application of energy to cause selective heating of the vein. The catheter is positioned within the vein to be treated, and the electrodes on the catheter are moved toward one side of the vein. RF energy is applied in a directional manner from the electrodes at the working end of the catheter to cause localized heating and corresponding shrinkage of the adjacent venous tissue, which may include commissures, leaflets and ostia. Fluoroscopy or ultrasound may be used to detect shrinkage of the vein. After treating one section of the vein, the catheter can be repositioned to place the electrodes to treat different sections of the vein until all desired venous valves are repaired and rendered functionally competent.
摘要翻译： 导管通过施加能量来引起静脉的选择性加热，将电极引入静脉中用于微创治疗静脉功能不全。 将导管定位在待治疗的静脉内，导管上的电极向静脉的一侧移动。 射频能量以定向方式从导管的工作端处的电极施加，以引起相邻静脉组织的局部加热和相应的收缩，其可以包括连合，小叶和口。 荧光透视或超声可用于检测静脉的收缩。 在治疗静脉的一部分之后，可以重新定位导管以放置电极来治疗静脉的不同部分，直到所有期望的静脉瓣被修复并具有功能上的能力。
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公开(公告)号：US6139527A
公开(公告)日：2000-10-31
申请号：US720209
申请日：1996-09-26
申请人： Michael D. Laufer , Brian E. Farley
发明人： Michael D. Laufer , Brian E. Farley
CPC分类号： A61B18/1492 , A61B18/08 , A61B2017/22051 , A61B2017/22097 , A61B2018/00083 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00285 , A61B2018/00404 , A61B2018/00488 , A61B2018/00702 , A61B2018/00755 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00875 , A61B2018/1253 , A61B2018/126 , A61B2018/1465 , A61B2018/1497
摘要： A catheter delivers an electrode within a vein for a minimally invasive treatment of hemorrhoids using RF energy. The catheter is introduced into a patient and positioned within the section of the vein to be treated. The electrode radiates high frequency energy towards the vein, and the surrounding venous tissue becomes heated and begins to shrink. The catheter includes a controllable member for limiting the amount of shrinkage of the vein to the diameter of the member. The electrode remains active until there has been sufficient shrinkage of the vein. The extent of shrinkage of the vein can be detected by fluoroscopy. After treating one section of the vein, the catheter and the electrode can be repositioned within the hemorrhoidal venous system to treat different sections until all desired venous sections and valves are repaired and rendered functionally competent. Shrinkage of the vein further thickens and stiffens the vein wall which reduces the potential for the hemorrhoid vein to dilate.
摘要翻译： 导管在静脉内输送电极，以使用RF能量对痔疮进行微创治疗。 将导管引入患者并定位在待治疗的静脉的部分内。 电极向静脉辐射高频能量，周围静脉组织变热并开始收缩。 导管包括可控制的构件，用于限制静脉的收缩量与构件的直径。 电极保持活动，直到静脉充分收缩。 静脉收缩程度可通过荧光透视法检测。 在治疗静脉的一部分之后，可以在痔静脉系统内重新定位导管和电极以治疗不同的部分，直到所有期望的静脉部分和瓣膜被修复并且具有功能上的能力。 静脉收缩进一步增厚并硬化静脉壁，减少痔疮静脉扩张的可能性。
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公开(公告)号：US6033397A
公开(公告)日：2000-03-07
申请号：US717994
申请日：1996-09-26
申请人： Michael D. Laufer , Brian E. Farley
发明人： Michael D. Laufer , Brian E. Farley
CPC分类号： A61B18/08 , A61B18/1492 , A61B2017/22051 , A61B2017/22097 , A61B2018/00083 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00285 , A61B2018/00404 , A61B2018/00488 , A61B2018/00755 , A61B2018/00797 , A61B2018/00875 , A61B2018/1253 , A61B2018/126 , A61B2018/1465 , A61B2018/1497
摘要： A catheter delivers an electrode within a vein for a minimally invasive treatment of esophageal varices using RF energy. The catheter is introduced into and positioned within the section of the vein to be treated. The electrode radiates high frequency energy towards the vein, and the surrounding venous tissue becomes heated and begins to shrink. The extent of shrinkage of the vein is detected by fluoroscopy. The electrode remains active until there has been sufficient shrinkage of the vein. The electrode may remain active for an extended period of time so as to promote a thickening of the immediately surrounding esophageal tissue. The catheter includes a controllable member for limiting the amount of shrinkage of the vein to the diameter of the member. After treating one section of the vein, the catheter and the electrode are repositioned within the venous system to treat different sections until all desired venous sections are rendered functionally competent.
摘要翻译： 导管在静脉内输送电极，以利用RF能量进行食管静脉曲张的微创治疗。 将导管引入并定位在待治疗的静脉的部分内。 电极向静脉辐射高频能量，周围的静脉组织变热并开始收缩。 通过荧光透视法检测静脉收缩程度。 电极保持活动，直到静脉充分收缩。 电极可以长时间保持活性，以促进立即周围食管组织的增厚。 导管包括可控制的构件，用于限制静脉的收缩量与构件的直径。 在处理静脉的一部分之后，将导管和电极重新定位在静脉系统内以处理不同部分，直到所有期望的静脉部分具有功能上的能力。
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公开(公告)号：US6135997A
公开(公告)日：2000-10-24
申请号：US193319
申请日：1998-11-16
申请人： Michael D. Laufer , Brian E. Farley
发明人： Michael D. Laufer , Brian E. Farley
CPC分类号： A61B18/1492 , A61B18/08 , A61B2017/22051 , A61B2017/22097 , A61B2018/00083 , A61B2018/00214 , A61B2018/0022 , A61B2018/00267 , A61B2018/00285 , A61B2018/00404 , A61B2018/00488 , A61B2018/00702 , A61B2018/00755 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00875 , A61B2018/1253 , A61B2018/126 , A61B2018/1465 , A61B2018/1497
摘要： A catheter delivers an electrode within a vein for a minimally invasive treatment of hemorrhoids using RF energy. The catheter is introduced into a patient and positioned within the section of the vein to be treated. The electrode radiates high frequency energy towards the vein, and the surrounding venous tissue becomes heated and begins to shrink. The catheter includes a controllable member for limiting the amount of shrinkage of the vein to the diameter of the member. The electrode remains active until there has been sufficient shrinkage of the vein. The extent of shrinkage of the vein can be detected by fluoroscopy. After treating one section of the vein, the catheter and the electrode can be repositioned within the hemorrhoidal venous system to treat different sections until all desired venous sections and valves are repaired and rendered functionally competent. Shrinkage of the vein further thickens and stiffens the vein wall which reduces the potential for the hemorrhoid vein to dilate.
摘要翻译： 导管在静脉内输送电极，以使用RF能量对痔疮进行微创治疗。 将导管引入患者并定位在待治疗的静脉的部分内。 电极向静脉辐射高频能量，周围静脉组织变热并开始收缩。 导管包括可控制的构件，用于限制静脉的收缩量与构件的直径。 电极保持活动，直到静脉充分收缩。 静脉收缩程度可通过荧光透视法检测。 在治疗静脉的一部分之后，可以在痔静脉系统内重新定位导管和电极以治疗不同的部分，直到所有期望的静脉部分和瓣膜被修复并且具有功能上的能力。 静脉收缩进一步增厚并硬化静脉壁，减少痔疮静脉扩张的可能性。
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