公开(公告)号：US09078764B2

公开(公告)日：2015-07-14

申请号：US12450717

申请日：2008-04-08

Applicant: Geraint Davies ,  John Cline ,  Christopher Gregory ,  Alan Cucknell ,  Julian Scarfe ,  Pete Cauwood

Inventor： Geraint Davies ,  John Cline ,  Christopher Gregory ,  Alan Cucknell ,  Julian Scarfe ,  Pete Cauwood

IPC: A61F5/441 ,  A61F5/445 ,  A61F5/44

CPC classification number: A61F5/445 ,  A61F5/4407 ,  A61F5/441

Abstract: A stoma closure that includes a conformable portion for conforming to an individual's stoma. The conformable portion includes a sack containing particles. The conformable portion may include a gel that may be loose or be at least partly contained in a sack. The conformable portion may include foam. The conformable portion may be configured to permit venting of flatus, while obstructing the passage of liquid/solid stool.

Abstract translation: 造口闭合，其包括适合于个体造口的适形部分。 适形部分包括含有颗粒的袋。 适形部分可以包括可能松散或至少部分地包含在袋中的凝胶。 适形部分可以包括泡沫。 适形部分可以被配置为允许排气，同时阻碍液体/固体粪便的通过。

公开(公告)号：US20140107572A1

公开(公告)日：2014-04-17

申请号：US14000384

申请日：2012-02-16

Applicant: Yun Jin ,  Christopher Gregory

Inventor： Yun Jin ,  Christopher Gregory

IPC: A61M25/10

CPC classification number: A61M25/10186 ,  A61F5/4405 ,  A61M5/3134 ,  A61M25/1018 ,  A61M25/10182 ,  A61M25/10184 ,  A61M25/1036 ,  A61M39/22 ,  A61M39/24 ,  A61M39/26 ,  A61M2039/2473 ,  A61M2039/2493 ,  Y10T29/49826

Abstract: The present invention relates to a valve system for an inflatable portion of an indwelling medical device and more particularly to a valve system for fluid regulation of a catheter comprising a fluid inflatable portion that undergoes pressure changes within the body during use. The present invention also relates to methods of treatment using said valve system and indwelling medical devices comprising said valve systems.

Abstract translation: 本发明涉及一种用于留置医疗装置的可膨胀部分的阀系统，更具体地涉及一种用于导管的流体调节的阀系统，该阀系统包括在使用期间在体内经受压力变化的流体可充气部分。 本发明还涉及使用所述阀系统和包括所述阀系统的留置医疗装置的治疗方法。

公开(公告)号：US08323254B2

公开(公告)日：2012-12-04

申请号：US11877691

申请日：2007-10-24

Applicant: Mingliang Lawrence Tsai ,  Christopher Gregory

Inventor： Mingliang Lawrence Tsai ,  Christopher Gregory

IPC: A61M1/00

CPC classification number: B29C63/42 ,  A61F5/44 ,  A61F5/445 ,  A61F2005/4455 ,  B29L2031/753 ,  B32B1/08 ,  B32B7/12 ,  B32B27/08 ,  B32B2307/7248 ,  B32B2319/00

Abstract: A tube assembly for carrying malodoriforous matter from the human body comprises a silicone based tube having a central bore for the malodoriforous matter, and a tubular sleeve member comprising an odor barrier material, the silicone based tube and the tubular sleeve member being arranged one within the other such that the tubular sleeve member provides an odor barrier to obstruct leakage of odors from malodoriforous matter in the bore of the silicone based tube. The tube assembly is especially suitable for use in fecal or bowel management apparatus.

Abstract translation: 用于从人体携带恶臭物质的管组件包括具有用于恶臭物质的中心孔的硅树脂管，以及包含气味阻挡材料的管状套管构件，所述硅基管和管状套筒构件布置在内 另一个使得管状套管构件提供气味屏障以阻止气味从硅氧烷基管的孔中的恶臭物质泄漏。 管组件特别适用于粪便或肠管理装置。

公开(公告)号：US20110256581A1

公开(公告)日：2011-10-20

申请号：US13142046

申请日：2009-12-23

Applicant: Christopher Gregory ,  John Pound

Inventor： Christopher Gregory ,  John Pound

IPC: C12Q1/02 ,  C12N5/02

CPC classification number: G01N33/5032 ,  G01N2400/22

Abstract: In a first aspect, the present invention provides a method of removing non-viable cells from a cell population, said method comprising contacting a cell population with a compound under conditions suitable to permit binding between the compound and any non-viable cells present in the cell culture and removing at least some of the compound from said cell population. The invention further provides compositions suitable for use in these methods, further uses of such compositions and various other systems and kits.

Abstract translation: 在第一方面，本发明提供从细胞群体中除去非活细胞的方法，所述方法包括使细胞群与化合物在适于允许化合物与存在于细胞中的任何非存活细胞之间结合的条件下接触化合物 细胞培养并从所述细胞群中除去至少一些化合物。 本发明还提供适用于这些方法的组合物，这种组合物和各种其它体系和试剂盒的进一步用途。

公开(公告)号：US20100285034A1

公开(公告)日：2010-11-11

申请号：US12746269

申请日：2008-12-05

Applicant: Christopher Gregory

Inventor： Christopher Gregory

IPC: A61K39/395 ,  C07K16/18 ,  G01N33/566 ,  C12N5/07 ,  G01N33/543 ,  A61P17/02 ,  A61P35/00 ,  A61P29/00 ,  A61P37/04

CPC classification number: C07K16/18 ,  A61K2039/505 ,  C07K16/44 ,  C07K2317/567 ,  G01N33/6854 ,  G01N2510/00

Abstract: Described are methods of separating viable cells, apoptotic cells and dead cells and antibodies or use in such methods. The antibodies may also be used in treatment of inflammatory disease, cancer and in wound healing.

Abstract translation: 描述了分离活细胞，凋亡细胞和死细胞和抗体或在这些方法中使用的方法。 抗体也可用于治疗炎性疾病，癌症和伤口愈合。

公开(公告)号：US20100174253A1

公开(公告)日：2010-07-08

申请号：US12664169

申请日：2008-06-11

Applicant: John Cline ,  Bret Weig ,  Christopher Gregory ,  John Blum

Inventor： John Cline ,  Bret Weig ,  Christopher Gregory ,  John Blum

IPC: A61F5/44

CPC classification number: A61F5/445 ,  A61F2005/4455

Abstract: A stoma adapter is described that is especially suited to a recessed stoma or a flush stoma. The stoma adapter effectively extends the discharge passage from the stoma, protects peristomal skin, and forms a bridge at the interface between the stoma and an ostomy appliance. The stoma adapter contains a substantially unobstructed discharge passage, at least for effluent flowing in a discharge direction. The stoma adapter includes a seal for sealing against the bowel wall. The stoma adapter has collapsing, expanding, flexible and reinforced designs.

Abstract translation: 描述了一种特别适用于凹陷造口或冲洗手术的造口适配器。 造口适配器有效地从造口延伸排出通道，保护周围皮肤，并在造口术和造口术器具之间的界面处形成桥。 造口适配器包含基本上无障碍的排放通道，至少对于在排放方向流动的流出物。 造口适配器包括用于密封肠壁的密封件。 造口适配器具有塌缩，膨胀，柔性和增强设计。

公开(公告)号：US20080103463A1

公开(公告)日：2008-05-01

申请号：US11877691

申请日：2007-10-24

Applicant: Mingliang Lawrence Tsai ,  Christopher Gregory

Inventor： Mingliang Lawrence Tsai ,  Christopher Gregory

IPC: A61M1/00 ,  B29C71/02 ,  B32B37/00

CPC classification number: B29C63/42 ,  A61F5/44 ,  A61F5/445 ,  A61F2005/4455 ,  B29L2031/753 ,  B32B1/08 ,  B32B7/12 ,  B32B27/08 ,  B32B2307/7248 ,  B32B2319/00

Abstract: A tube assembly for carrying malodoriforous matter from the human body comprises a silicone based tube having a central bore for the malodoriforous matter, and a tubular sleeve member comprising an odor barrier material, the silicone based tube and the tubular sleeve member being arranged one within the other such that the tubular sleeve member provides an odor barrier to obstruct leakage of odors from malodoriforous matter in the bore of the silicone based tube. The tube assembly is especially suitable for use in fecal or bowel management apparatus.

Abstract translation: 用于从人体携带恶臭物质的管组件包括具有用于恶臭物质的中心孔的硅树脂管，以及包含气味阻挡材料的管状套管构件，所述硅基管和管状套筒构件布置在内 另一个使得管状套管构件提供气味屏障以阻止气味从硅氧烷基管的孔中的恶臭物质泄漏。 管组件特别适用于粪便或肠管理装置。

公开(公告)号：US20080064981A1

公开(公告)日：2008-03-13

申请号：US11857493

申请日：2007-09-19

Applicant: Christopher Gregory

Inventor： Christopher Gregory

IPC: A61B5/053

CPC classification number: A61B5/0536 ,  A61B5/1077

Abstract: An electrical parameter imaging apparatus and method includes the acquisition of a charge distribution pattern on an array of electrodes that surround an object being imaged. In addition the boundaries of regions having differing electrical characteristics within the object are measured by a secondary imaging method. The internal boundary location measurements are employed to provide a quicker method to compute electrical parameters of tissues inside the boundary using the acquired charge distribution pattern.

Abstract translation: 电参数成像装置和方法包括在围绕被成像对象的电极阵列上获取电荷分布图案。 此外，通过二次成像方法测量物体内具有不同电特性的区域的边界。 采用内部边界位置测量来提供使用获取的电荷分布模式来计算边界内的组织的电参数的更快的方法。

公开(公告)号：US20080015405A1

公开(公告)日：2008-01-17

申请号：US11776321

申请日：2007-07-11

Applicant: Geraint Davies ,  John Cline ,  Christopher Gregory ,  Alan Cucknell ,  Julian Scarfe ,  Pete Cauwood

Inventor： Geraint Davies ,  John Cline ,  Christopher Gregory ,  Alan Cucknell ,  Julian Scarfe ,  Pete Cauwood

IPC: A61F5/445

CPC classification number: A61F5/445

Abstract: An ostomy plug is described comprising first and second chambers having adjacent ends coupled to, and in fluid communication with, each other. The first chamber may be for insertion into a stoma. The second chamber may contain fluid for inflating the first chamber when the second chamber is squeezed or otherwise compressed. The plug may have a figure-of-eight configuration. The plug may be configured to permit venting of flatus while obstructing escape of other body waste from the stoma. The plug may incorporate an insertion aid for aiding insertion into a stoma. The plug may also incorporate a device for regulating the inflation pressure of the fluid to avoid undesirably high inflation pressures in the stoma.

Abstract translation: 描述了一种造口术塞子，其包括具有彼此联接并彼此流体连通的相邻端部的第一和第二腔室。 第一腔可以插入造口。 当第二室被挤压或以其它方式被压缩时，第二室可以包含用于使第一室膨胀的流体。 插头可能具有八位配置。 塞子可以被配置为允许排气，同时阻止其他身体废物从造口排出。 插塞可以包括用于辅助插入造口的插入辅助件。 插塞还可以包括用于调节流体的充气压力的装置，以避免造口中不期望的高的充气压力。

公开(公告)号：US20070238647A1

公开(公告)日：2007-10-11

申请号：US11808801

申请日：2007-06-13

Applicant: Richard Bowen ,  Christopher Gregory

Inventor： Richard Bowen ,  Christopher Gregory

IPC: A61K48/00

CPC classification number: A61K38/09

Abstract: Methods are provided for treating prostate cancer, preventing or slowing proliferation of cells of prostate origin, preventing prostate cancer in a patient at risk of contracting prostate cancer, preventing or inhibiting an upregulation of the cell cycle in prostate-derived cells in a patient, and decreasing the level of prostate-specific antigen in a patient.