Abstract:
A method for transfecting T cells with a nucleic acid molecule comprising a gene such that the gene is expressed in the T cells is described. The T cells are stimulated and proliferating prior to introduction of the nucleic acid molecule.
Abstract:
Methods for protecting a T cell from cell death are described. The methods involve contacting the T cell with an agent which augments the bcl-XL protein level in the T cell such that it is protected from cell death. The invention further pertains to methods for increasing the susceptibility of a T cell to cell death, comprising contacting the T cell with at least one agent which decreases bcl-XL protein level in the T cell. Both in vivo and in vitro methods are described.
Abstract translation:描述了保护T细胞免于细胞死亡的方法。 所述方法包括使T细胞与增加T细胞中的bcl-X L L蛋白水平的试剂接触,使得其被保护免于细胞死亡。 本发明还涉及增加T细胞对细胞死亡的易感性的方法,包括使T细胞与降低T细胞中bcl-XL蛋白水平的至少一种试剂接触。 描述体内和体外方法。
Abstract:
A display board that may be supported on an easel stand includes a panel having a display surface on a front side thereof. A mounting interface is positioned adjacent a top edge of the panel and is configured for engagement with any one of a plurality of unique easel stand securing means.
Abstract:
A method and apparatus for isolating electronic devices from mechanical shock and thermal environments utilizes a metal outer protective shell surrounding the electronic device to be protected. Interposed between the protective shell and the electronic device are a thermal insulating layer, a layer of phase change material and a layer of mechanical shock absorbent material.
Abstract:
A device for mounting an item on a surface includes a base plate having front and rear major surfaces, a fastener for securing the base plate to the surface, and a retaining member removably connected with the base plate front major surface to retain the item on the device.