公开(公告)号：US20100279233A1

公开(公告)日：2010-11-04

申请号：US12738598

申请日：2008-10-08

申请人： Tae-Su Kim ,  Jae-Jin Kim ,  Hyun-Woo Shin

发明人： Tae-Su Kim ,  Jae-Jin Kim ,  Hyun-Woo Shin

IPC分类号： G03F7/20

CPC分类号： G03F7/70408 ,  G02B5/1809 ,  G02B5/1814

摘要： A method for laser interference lithography using a diffraction grating includes (a) forming a photoresist layer on a work substrate to which a repeated fine pattern is to be formed; (b) forming a refractive index matching material layer on the photoresist layer; (c) forming on the refractive index matching material layer a diffraction grating layer having a period of diffraction grating within the range from λ/ng to λ/n0 (λ is a wavelength of laser beam, ng is a refractive index of the diffraction grating, and n0 is a refractive index in the air or in vacuum); and (d) exposing the photoresist layer by means of mutual interference of positive and negative diffracted lights with the same absolute value by inputting a laser beam perpendicularly to the diffraction grating layer. This method allows to realize an interference pattern with higher resolution and to use a laser source with lower coherence.

摘要翻译： 使用衍射光栅的激光干涉光刻方法包括：（a）在要形成重复精细图案的工件基板上形成光致抗蚀剂层; （b）在光致抗蚀剂层上形成折射率匹配材料层; （c）在折射率匹配材料层上形成具有λ/ ng至λ/ n0范围内的衍射光栅周期的衍射光栅层（λ为激光束的波长，ng为衍射光栅的折射率 ，n0是空气中或真空中的折射率）; 和（d）通过垂直于衍射光栅层输入激光束，通过相同绝对值的正和负衍射光的相互干涉来使光致抗蚀剂层曝光。 该方法允许实现具有更高分辨率的干涉图案并且使用具有较低相干性的激光源。

公开(公告)号：US20100098762A1

公开(公告)日：2010-04-22

申请号：US12573037

申请日：2009-10-02

申请人： Dong Keun Han ,  Kwideok Park ,  Jae-Jin Kim

发明人： Dong Keun Han ,  Kwideok Park ,  Jae-Jin Kim

IPC分类号： A61K9/10 ,  A61K38/18 ,  A61K38/06 ,  A61K38/07 ,  A61K38/08 ,  A61P19/04

CPC分类号： A61K9/06 ,  A61K47/10 ,  A61K47/60

摘要： The present invention relates to a thermosensitive pluronic derivative hydrogel for tissue regeneration in which a biodegradable polymer is introduced at one end or both ends of a pluronic polymer, a methacryloxyethyl trimellitic acid anhydride is conjugated to the biodegradable polymer, and a physiologically active substance is fixed to the methacryloxyethyl trimellitic acid anhydride, as well as a method for the preparation thereof. The pluronic derivative hydrogel according to the present invention exhibits high biodegradability due to the introduction of a biodegradable polymer while still maintaining the themosensitivity of the pluronic polymer itself and shows good biocompatibility owing to the coupling with a physiologically active substance capable of improving cell adhesion, proliferation and differentiation. Therefore, the pluronic derivative hydrogel according to the present invention can be effectively used in the regeneration of various kinds of tissues and organs.

摘要翻译： 本发明涉及用于组织再生的热敏普朗尼克衍生物水凝胶，其中在聚醚聚合物的一端或两端引入可生物降解的聚合物，将甲基丙烯酰氧基乙基偏苯三酸酐与可生物降解的聚合物缀合，并且将生理活性物质固定 到甲基丙烯酰氧基乙基偏苯三酸酐，以及其制备方法。 本发明的聚醚衍生物水凝胶由于引入生物可降解聚合物而具有高生物降解性，同时仍然保持了普鲁隆聚合物本身的敏感性，并且由于与能够改善细胞粘附，增殖的生理活性物质的偶联而显示出良好的生物相容性 和分化。 因此，根据本发明的普流纶衍生物水凝胶可以有效地用于各种组织和器官的再生。

公开(公告)号：US06463790B1

公开(公告)日：2002-10-15

申请号：US09678829

申请日：2000-10-04

申请人： Myung-Suk Chun ,  Jae-Jin Kim ,  Sang-Yup Lee

发明人： Myung-Suk Chun ,  Jae-Jin Kim ,  Sang-Yup Lee

IPC分类号： G01N1104

CPC分类号： B01D65/102 ,  B01D61/22 ,  G01N15/0826 ,  G01N2015/0088 ,  G01N2015/086

摘要： A membrane filtration method and an apparatus for continuously monitoring the state of a membrane during the filtration, particularly for membrane fouling due to cake or gel layers of solutes developed on the surfaces of a filtered membrane, by estimating a membrane potential and a membrane solute rejection while making measurements of a set of physical properties of feed, variations of a streaming potential difference across pores of the membrane, variation in pressure differences between an upstream side and a downstream side of the membrane, and concentration differences between the feed and permeate filtered through the membrane.

摘要翻译： 一种膜过滤方法和用于连续监测过滤期间膜的状态的装置，特别是由于滤膜表面上形成的溶质的饼状物或凝胶层而导致的膜污染，通过估计膜电位和膜溶质排斥 同时测量饲料的一组物理性质，穿过膜孔的流动电位差的变化，膜的上游侧和下游侧之间的压力差的变化以及通过过滤的进料和渗透物之间的浓度差异 膜。