公开(公告)号：US20220026361A1

公开(公告)日：2022-01-27

申请号：US17297427

申请日：2018-12-18

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Fausto D'Apuzzo ,  Steven Barcelo ,  Raghuvir N. Sengupta

IPC: G01N21/64 ,  G01N21/65

Abstract: In an example method, an ordered array of microdots including an analyte printed on a surface of a surface-enhanced substrate of an analysis chip is probed with an excitation beam of electromagnetic radiation. Emitted radiation is detected from a number of microdots of the ordered array of microdots. Calibration data is generated for the analysis chip with respect to the analyte based on a detected shift in the emitted radiation as compared to the excitation beam.

公开(公告)号：US20210080323A1

公开(公告)日：2021-03-18

申请号：US16611968

申请日：2017-07-19

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Steven Barcelo ,  Anita Rogacs

IPC: G01J3/44 ,  G01N21/65 ,  G01N21/64

Abstract: A spectroscopic device is provided. The spectroscopic device includes a plurality of design groups on a substrate. Each design group includes a plurality of collapsed groups separated by bare regions of substrate, wherein the edges of each design group is configured to enhance the pinning of a solvent drying line at the edge of the design group. Each collapsed group comprises at least 2 flexible columnar structures, and each flexible columnar structure comprises a metal cap.

公开(公告)号：US10828637B2

公开(公告)日：2020-11-10

申请号：US15792732

申请日：2017-10-24

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Steven Barcelo ,  Anita Rogacs ,  Viktor Shkolnikov ,  Milo Overbay

IPC: B01L3/00 ,  G01N21/64 ,  B29C39/00 ,  B01L9/00 ,  A61K49/00 ,  G01N21/65

Abstract: A microfluidic chip may include a substrate, chamber supported by the substrate, a sacrificial material in the chamber, a spectroscopically active nano particle assembly anchored within the chamber by the sacrificial material and a fluid supply port connected to the chamber. Each spectroscopically active nano particle assembly may include a cluster of nanoparticles.

公开(公告)号：US20200256800A1

公开(公告)日：2020-08-13

申请号：US16606429

申请日：2017-10-24

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Steven Barcelo ,  Anita Rogacs ,  Raghuvir N. Sengupta

IPC: G01N21/65 ,  B82Y15/00

Abstract: A surface enhanced luminescence analyte nano pillar stage may include a substrate, an array of closable pillars extending from the substrate and a fluid supply connected to the array of pillars. The fluid supply is to at least partially replenish fluid amongst the pillars of the array that has evaporated to maintain a level of the fluid amongst the pillars of the array below tops of the pillars.

公开(公告)号：US10724959B2

公开(公告)日：2020-07-28

申请号：US15764322

申请日：2015-11-13

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Ning Ge ,  Steven Barcelo ,  Anita Rogacs ,  Helen A Holder

IPC: G01J3/44 ,  G01N21/65 ,  G01N27/22 ,  G01N33/04 ,  G01N21/64 ,  G01N1/44 ,  B01L3/00 ,  G01N33/22

Abstract: In an example implementation, a substance detection method includes sensing for fluid in a chamber of a substance detection device. When fluid is sensed in the chamber, the method includes sensing again for fluid in the chamber. When no fluid is sensed in the chamber, the method includes initiating a substance detection process.