公开(公告)号：US07904142B2

公开(公告)日：2011-03-08

申请号：US11749283

申请日：2007-05-16

申请人： Jaeho Kim ,  Joseph M. Bocek ,  Dan Li

发明人： Jaeho Kim ,  Joseph M. Bocek ,  Dan Li

IPC分类号： A61B5/0402

CPC分类号： A61B5/0422 ,  A61N1/3622 ,  A61N1/3931 ,  A61N1/3962

摘要： An apparatus comprising an implantable cardiac signal sensing circuit configured for sensing an intrinsic cardiac signal, a memory to store a template of a morphology of normal atrial-ventricular conduction, and a controller that includes a tachyarrhythmia detection circuit and a correlation circuit. The tachyarrhythmia detection circuit is configured for detecting a rhythm with elevated ventricular rate using the sensed intrinsic cardiac signal. The correlation circuit is configured for iteratively calculating a correlation between the sensed intrinsic cardiac signal and the template, and comparing the calculated correlation to a variable correlation threshold to determine whether the detected rhythm correlates to the template. The apparatus also includes a therapy circuit configured for inhibiting a ventricular tachycardia therapy when the detected rhythm correlates to the template. Other apparatuses and methods are described.

摘要翻译： 一种装置，包括被配置为感测本征心脏信号的可植入心脏信号感测电路，存储器以存储正常心室传导形态的模板，以及包括快速性心律失常检测电路和相关电路的控制器。 快速心律失常检测电路被配置为使用感测到的本征心脏信号来检测具有升高的心室率的节律。 相关电路被配置为迭代地计算所感测的本征心脏信号与模板之间的相关性，并将所计算的相关性与可变相关阈值进行比较，以确定检测到的节律是否与模板相关。 该装置还包括治疗电路，其被配置为当检测到的节律与模板相关时抑制室性心动过速治疗。 描述其他设备和方法。

公开(公告)号：US07890170B2

公开(公告)日：2011-02-15

申请号：US12838626

申请日：2010-07-19

申请人： Benjamin Ettori ,  Joseph M. Bocek ,  Jaeho Kim

发明人： Benjamin Ettori ,  Joseph M. Bocek ,  Jaeho Kim

IPC分类号： A61N1/00

CPC分类号： A61B5/04525 ,  A61B5/0464

摘要： A cardiac rhythm management system can be used to detect episode beats associated with cardiac events in a subject's body. These events may be monitored and depolarization morphology information can be derived for candidate arrhythmic beats in an arrhythmia episode. An arrhythmic beat morphology template may be formed from selecting at least one of the candidate arrhythmic beats based upon user's labeling according to specific morphologies of one or more candidate episodes. Methods of use are also presented.

摘要翻译： 可以使用心律管理系统来检测与受试者体内心脏事件相关的发作次数。 可以监测这些事件，并且可以在心律失常发作中为候选心律失常节拍导出去极化形态信息。 可以根据一个或多个候选事件的特定形态，基于用户的标签选择候选心律失常节拍中的至少一个来形成心律失常搏动形态模板。 还介绍了使用方法。

公开(公告)号：US20100298902A1

公开(公告)日：2010-11-25

申请号：US12849714

申请日：2010-08-03

申请人： Jaeho Kim ,  Joseph M. Bocek

发明人： Jaeho Kim ,  Joseph M. Bocek

IPC分类号： A61N1/365

CPC分类号： A61N1/3621 ,  A61N1/3925

摘要： This document discusses, among other things, detection of a sudden onset of a tachyarrhythmia. A sudden onset of tachyarrhythmia is determined by monitoring changes in intrinsic ventricular rate, such as by using one or more sensing channels in the ICD. A lowest tachyarrhythmia rate threshold is accompanied by a slightly lower “hysteresis tachyarrhythmia rate threshold.” If a sudden onset of tachyarrhythmia is declared, the sudden onset status is not reset by the ventricular rate falling below the lowest tachyarrhythmia rate threshold, but is instead reset by the ventricular rate falling below the slightly lower hysteresis tachyarrhythmia rate threshold.

摘要翻译： 本文件尤其涉及突发性快速性心律失常发作的检测。 通过监测内在心室率的变化，例如通过使用ICD中的一个或多个感测通道来确定快速性心律失常的突然发作。 最低的快速性心律失常率阈值伴随着稍低的“滞后快速性心律失常率阈值”。如果宣布出现快速性心律失常发作，则突发发作状态不会因心律失常率低于最低心律失常率阈值而重置，而是重置 由心律失常率低于滞后快速性心律失常率阈值。

公开(公告)号：US20100280400A1

公开(公告)日：2010-11-04

申请号：US12838626

申请日：2010-07-19

申请人： Benjamin Ettori ,  Joseph M. Bocek ,  Jaeho Kim

发明人： Benjamin Ettori ,  Joseph M. Bocek ,  Jaeho Kim

IPC分类号： A61B5/0402

CPC分类号： A61B5/04525 ,  A61B5/0464

摘要： A cardiac rhythm management system can be used to detect episode beats associated with cardiac events in a subject's body. These events may be monitored and depolarization morphology information can be derived for candidate arrhythmic beats in an arrhythmia episode. An arrhythmic beat morphology template may be formed from selecting at least one of the candidate arrhythmic beats based upon user's labeling according to specific morphologies of one or more candidate episodes. Methods of use are also presented.

摘要翻译： 可以使用心律管理系统来检测与受试者体内心脏事件相关的发作次数。 可以监测这些事件，并且可以在心律失常发作中为候选心律失常节拍导出去极化形态信息。 可以根据一个或多个候选事件的特定形态，基于用户的标签选择候选心律失常节拍中的至少一个来形成心律失常搏动形态模板。 还介绍了使用方法。

公开(公告)号：US07774062B2

公开(公告)日：2010-08-10

申请号：US11301440

申请日：2005-12-13

申请人： Jaeho Kim ,  Joseph M. Bocek

发明人： Jaeho Kim ,  Joseph M. Bocek

IPC分类号： A61N1/00

CPC分类号： A61N1/3621 ,  A61N1/3925

摘要： This document discusses, among other things, detection of a sudden onset of a tachyarrhythmia. A sudden onset of tachyarrhythmia is determined by monitoring changes in intrinsic ventricular rate, such as by using one or more sensing channels in the ICD. A lowest tachyarrhythmia rate threshold is accompanied by a slightly lower “hysteresis tachyarrhythmia rate threshold.” If a sudden onset of tachyarrhythmia is declared, the sudden onset status is not reset by the ventricular rate falling below the lowest tachyarrhythmia rate threshold, but is instead reset by the ventricular rate falling below the slightly lower hysteresis tachyarrhythmia rate threshold.

摘要翻译： 本文件尤其涉及突发性快速性心律失常发作的检测。 通过监测内在心室率的变化，例如通过使用ICD中的一个或多个感测通道来确定快速性心律失常的突然发作。 最低的快速性心律失常率阈值伴随着稍低的“滞后快速性心律失常率阈值”。如果宣布出现快速性心律失常发作，则突发发作状态不会因心律失常率低于最低心律失常率阈值而重置，而是重置 由心律失常率低于滞后快速性心律失常率阈值。

公开(公告)号：US20080147132A1

公开(公告)日：2008-06-19

申请号：US12069451

申请日：2008-02-08

申请人： Bijan Elahi ,  Joseph M. Bocek ,  Jaeho Kim

发明人： Bijan Elahi ,  Joseph M. Bocek ,  Jaeho Kim

IPC分类号： A61N1/39

CPC分类号： A61N1/3962 ,  A61N1/3622

摘要： An implantable cardioverter/defibrillator (ICD) executes a rate accuracy enhancement algorithm to select measured atrial and ventricular intervals for classifying a detected tachycardia based on average atrial and ventricular rates calculated from the selected atrial and ventricular intervals. The detected tachycardia is classified as ventricular tachycardia (VT) if the average ventricular rate is substantially higher than the average atrial rate.

公开(公告)号：US6047210A

公开(公告)日：2000-04-04

申请号：US146948

申请日：1998-09-03

申请人： Jaeho Kim ,  Joseph M. Bocek

发明人： Jaeho Kim ,  Joseph M. Bocek

IPC分类号： A61N1/362 ,  A61N1/39 ,  A61N1/05

CPC分类号： A61N1/3962 ,  A61N1/3622

摘要： An atrial cardioverter for cardioverting atria of a heart while sustaining atrial pacing of the heart. The cardioverter includes a pacer for pacing the heart in one of a plurality of modes including an atrial pacing, atrial inhibited mode, and an atrial pacing, ventricular inhibited mode, an atrial tachyarrhythmia detector for detecting an atrial tachyarrhythmia of the heart, and a mode control for changing the mode of the pacer from the atrial pacing, atrial inhibited mode to the atrial pacing, ventricular inhibited mode responsive to the atrial tachyarrhythmia detector detecting an atrial tachyarrhythmia of the heart. A cardioverter stage applies cardioverting energy to the atria responsive to the atrial tachyarrhythmia detector detecting an atrial tachyarrhythmia and after the pacer mode change.

摘要翻译： 一个心脏心律转复者心脏心脏的心脏转移，同时维持心脏的心房起搏。 心脏复律器包括用于将心脏起搏以包括心房起搏，心房抑制模式和心房起搏，心室抑制模式，用于检测心脏心房心动过速的房性快速性心律失常检测器的多种模式之一起搏的起搏器，以及模式 控制将起搏器的模式从心房起搏，心房抑制模式改变为心房起搏，响应于心房快速性心律失常检测器检测心脏心律失常的心室抑制模式。 心律转复阶段对心房颤动检测器检测心房快速性心律失常并且在起搏器模式改变之后对心房施加心脏转复能量。

公开(公告)号：US5486199A

公开(公告)日：1996-01-23

申请号：US278055

申请日：1994-07-20

申请人： Jaeho Kim ,  Harley G. White

发明人： Jaeho Kim ,  Harley G. White

IPC分类号： A61N1/39

CPC分类号： A61N1/3956 ,  A61N1/395 ,  A61N1/3987

摘要： An implantable atrial defibrillator applies cardioverting electrical energy to the atria of a human heart in need of cardioversion after first determining if there is an absence of potential atrial fibrillation. A sensor associated with the atria of the heart senses activity of the heart and generates a cardiac signal and a first detector detects cardiac events from the cardiac signal. A second detector responsive to time spans between immediately successive detected cardiac events which are grater in duration than a preselected interval detects for an absence of potential atrial fibrillation. An atrial fibrillation detector detects for atrial fibrillation if the second detector fails to detect an absence of atrial fibrillation, and a cardiovertor applies cardioverting electrical energy to the atria when the atria are in fibrillation.

摘要翻译： 可植入心房除颤器首先确定是否存在潜在的心房纤维性颤动之后，将心脏转移电能应用于需要心脏复律的人心脏心房。 与心脏心房相关联的传感器感测心脏的活动并产生心脏信号，第一检测器从心脏信号检测心脏事件。 响应时间跨度的第二检测器，其在比预选间隔更长的持续时间检测到的心脏事件之间，检测不存在潜在心房颤动。 心房颤动检测器检测心房颤动如果第二检测器不能检测到心房纤维性颤动，而心房转移器在心房颤动时将心脏电能施加到心房。

公开(公告)号：US08437849B2

公开(公告)日：2013-05-07

申请号：US11668627

申请日：2007-01-30

申请人： Jaeho Kim ,  Joseph M. Bocek ,  Dan Li

发明人： Jaeho Kim ,  Joseph M. Bocek ,  Dan Li

IPC分类号： A61N1/372 ,  A61N1/39

CPC分类号： A61N1/3962 ,  A61B5/0452 ,  A61B5/04525 ,  A61B5/0464 ,  A61B5/7264 ,  A61N1/3925

摘要： An implantable cardioverter/defibrillator (ICD) delivers atrial pacing under several scenarios during a tachyarrhythmia episode that is detected using a ventricular rate. In various embodiments, the atrial pacing terminates the detected tachyarrhythmia and/or enhances the classification of the detected tachyarrhythmia, thus avoiding ineffective and/or unnecessary delivery of a ventricular anti-tachyarrhythmia therapy when the detected tachyarrhythmia has a supraventricular origin.

摘要翻译： 植入式心律转复除颤器（ICD）在使用心室率检测到的快速性心律失常发作期间在几种情况下提供心房起搏。 在各种实施方案中，心房起搏终止所检测到的快速性心律失常和/或增强检测到的快速性心律失常的分类，从而避免了当检测到的快速性心律失常具有室上性起源时，无效和/或不必要地输送室性抗快速性心律失常治疗。

公开(公告)号：US08301244B2

公开(公告)日：2012-10-30

申请号：US12552614

申请日：2009-09-02

申请人： Jaeho Kim ,  Dan Li ,  Joseph M. Bocek

发明人： Jaeho Kim ,  Dan Li ,  Joseph M. Bocek

IPC分类号： A61B5/046

CPC分类号： A61N1/3621 ,  A61B5/0464 ,  A61N1/365 ,  A61N1/3962

摘要： An apparatus comprises an implantable ventricular depolarization sensing circuit configured to provide a sensed ventricular depolarization signal, a timer circuit configured to provide a ventricular time interval between ventricular depolarizations, and a controller circuit communicatively coupled to the ventricular depolarization sensing circuit and the timer circuit. The controller circuit includes a ventricular tachycardia (VT) detection circuit configured to declare an episode of VT when a number of accelerated beats are detected, calculate a hysteresis VT detection threshold interval, and deem whether the episode of VT persists using the hysteresis VT detection threshold interval.

摘要翻译： 一种装置包括可植入心室去极化感测电路，其被配置为提供感测到的心室去极化信号，定时器电路，其被配置为提供心室去极化之间的心室时间间隔，以及通信地耦合到心室去极化感测电路和定时器电路的控制器电路。 所述控制器电路包括心室性心动过速（VT）检测电路，其被配置为当检测到多个加速搏动时声明VT的发作，计算滞后VT检测阈值间隔，并且使用滞后VT检测阈值来确定VT的发作是否持续 间隔。