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公开(公告)号:US20070267167A1
公开(公告)日:2007-11-22
申请号:US10552496
申请日:2004-04-14
申请人: James Kang
发明人: James Kang
CPC分类号: B22D25/005 , B22D11/0611 , B22D11/0622 , B22D11/0631 , C22C1/08 , C22C2001/086
摘要: Methods and apparatuses for the continuous casting of solid foam structures with varying bubble density from bulk solidifying amorphous alloys are provided. Continuously cast solid foam structures having bubble densities in the range of from 50 percent up to 95% by volume are also provided.
摘要翻译: 提供了从大量固化非晶合金连续铸造具有不同气泡密度的固体泡沫结构的方法和装置。 还提供了具有泡沫密度在50%至95%(体积)范围内的固体泡沫结构。
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公开(公告)号:US20060089346A1
公开(公告)日:2006-04-27
申请号:US10528640
申请日:2003-10-02
申请人: Christopher Becker , Bruce Dembofsky , Robert Jacobs , James Kang , Cyrus Ohnmacht , James Rosamond , Ashokkumar Shenvi , Thomas Simpson , James Woods
发明人: Christopher Becker , Bruce Dembofsky , Robert Jacobs , James Kang , Cyrus Ohnmacht , James Rosamond , Ashokkumar Shenvi , Thomas Simpson , James Woods
IPC分类号: A61K31/554 , A61K31/55 , A61K31/551
CPC分类号: C07K5/06034 , A61K38/00 , C07D223/16 , C07D267/10 , C07D267/14 , C07D281/06 , C07D281/10 , C07D405/04 , C07D417/12 , C07D417/14 , C07K5/06026 , C07K5/06191
摘要: Compounds having the formula (1) pharmaceutical compositions containing them and their methods of use for the treatment of neurological disorders related to amyloid B protein production and neurological disorders such as Alzheimer's disease. These compounds inhibit γ secretase and thereby inhibit the production of amyloid β protein, thereby acting to prevent the formation of neurological deposits of amyloid protein.
摘要翻译: 具有式(1)的药物组合物及其用于治疗与淀粉样蛋白B蛋白质产生和神经障碍如阿尔茨海默病相关的神经障碍的方法。 这些化合物抑制γ分泌酶,从而抑制淀粉样蛋白β蛋白的产生,从而起到防止淀粉样蛋白的神经沉积的形成的作用。
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