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公开(公告)号:US07026445B2
公开(公告)日:2006-04-11
申请号:US08949904
申请日:1997-10-15
摘要: Purified human SDF-5 proteins and processes for producing them are disclosed. DNA molecules encoding the human SDF-5 proteins are also disclosed. The proteins may be used in regulating the binding of Wnt genes to their receptor. In preferred embodiments, the proteins may be used for inducing formation, growth, differentiation, proliferation and/or maintenance of chondrocytes and/or cartilage tissue, and for other tissue repair, such as pancreatic tissue repair.
摘要翻译: 公开了纯化的人SDF-5蛋白质及其生产方法。 还公开了编码人SDF-5蛋白的DNA分子。 蛋白质可用于调节Wnt基因与其受体的结合。 在优选的实施方案中,蛋白质可用于诱导软骨细胞和/或软骨组织的形成,生长,分化,增殖和/或维持,以及用于其它组织修复,例如胰腺组织修复。