公开(公告)号：US5104982A

公开(公告)日：1992-04-14

申请号：US498262

申请日：1990-03-23

申请人： Randall L. Halcomb ,  Samuel J. Danishefsky ,  Mark D. Wittman

发明人： Randall L. Halcomb ,  Samuel J. Danishefsky ,  Mark D. Wittman

IPC分类号： C07D307/30 ,  C07D309/10 ,  C07D309/28 ,  C07D309/30 ,  C07D407/04 ,  C07D407/14 ,  C07H1/00 ,  C07H11/00 ,  C07H15/14 ,  C07H15/18 ,  C07H15/203 ,  C07H17/00

CPC分类号： C07H15/14 ,  C07D309/10 ,  C07D309/30 ,  C07H11/00 ,  C07H15/203 ,  C07H17/00

摘要： Axial anomeric sulfoxides generated via thiophenol Ferrier rearrangement of glucal and galactal derivatives are used to synthesize glycals of the gulal and allal series. An application of the method led to the synthesis of the esperamicin thiosugar.