摘要:
The present invention provides a nitrogen-containing heterocyclic compound or a pharmaceutically acceptable salt thereof having an inhibitory effect on the production of kynurenine, represented by formula (I): (wherein R6 and R7 may be the same or different and each represent a hydrogen atom or the like, R8, R9, R10, and R11 may be the same or different and each represent a hydrogen atom or the like, R1 represents lower alkyl which may be substituted with cycloalkyl, or the like, and R3 represents optionally substituted aryl or an optionally substituted heterocyclic group).
摘要翻译:本发明提供对由式(I)表示的对犬尿胆碱的产生具有抑制作用的含氮杂环化合物或其药学上可接受的盐:(其中R 6和R 7可以相同或不同,各自表示氢原子 R 8,R 10和R 11可以相同或不同,各自表示氢原子等,R 1表示可以被环烷基取代的低级烷基等,R 3表示任意取代的芳基或 任选取代的杂环基)。
摘要:
Provided is a kynurenine production inhibitor comprising a nitrogen-containing heterocyclic compound represented by formula (I): (wherein R50 and R51 may be the same or different and each represent a hydrogen atom or the like, G1 and G2 may be the same or different and each represent a nitrogen atom or the like, X represents formula (III): (wherein m1 and m2 may be the same or different and each represent an integer of 0 or 1, Y represents an oxygen atom or the like, and R6 and R7 may be the same or different and each represent a hydrogen atom or the like), R1 represents optionally substituted lower alkyl or the like, R2 represents a hydrogen atom or the like, and R3 represents optionally substituted lower alkyl or the like), and the like.
摘要翻译:本发明提供了含有由式(I)表示的含氮杂环化合物的犬尿氨酸生产抑制剂:其中R50和R51可以相同或不同,各自表示氢原子等,G1和G2可以相同或不同 各自表示氮原子等,X表示式(III):(其中,m1和m2可以相同或不同,表示0或1的整数,Y表示氧原子等,R6和 R 7可以相同或不同,各自表示氢原子等),R 1表示任选取代的低级烷基等,R 2表示氢原子等,R 3表示任选取代的低级烷基等),和 类似。
摘要:
A cleaning member includes a cleaning part whose one end portion comes into contact with a surface of an image carrier, and a supporting part that supports the cleaning part and applies a force for pressing the one end portion of the cleaning part to the surface of the image carrier, wherein a surface of a first portion including the one end portion of the cleaning part is bonded to the supporting part with a first adhesive layer, and a surface of a second portion including the other end portion opposite to the one end portion of the cleaning part is bonded to the supporting part with a second adhesive layer having a Type-A durometer hardness which is lower than that of the first adhesive layer.
摘要:
A magnetostrictive torque sensor having a rotating shaft on which at least one magnetostrictive film is formed, and has such a structure that the rotating shaft has small diameter portions and large diameter portions positioned on both end sides of the small diameter portions, and a length in an axial direction of the small diameter portion is determined in relation to a coil width of an induction heating coil to be used at a high frequency heating step and one magnetostrictive film is formed in the small diameter portion.
摘要:
A handle grip member with electric heater can be produced in high yield through simple processing not using any core of synthetic resin and avoiding molding operation. Depressed groove (4) is spirally provided on an external surface of inner part (1) of rubber, and multiple ribs (5) are provided on an internal surface thereof along the direction of length. Electric heater (7) of tape-shaped metal conductor is implanted in the depressed groove (4), and fixed. Electric wires (8a,8b) are connected to two ends of the electric heater (7) and drawn out. The inner part (1) is inserted in outer part (9) of rubber tube, and the outer part (9) is fixed to the inner part (1) with the use of an adhesive, etc.
摘要:
An image forming apparatus includes an image carrying body, a heating unit, a pressure unit for applying pressure, a recording medium supporting member, and a depressing/close-contacting unit. The recording medium supporting member moves in the same direction as the image carrying body moves, from a pressure position where the pressure unit applies pressure to the recording medium and the image carrying body to an exfoliation position where the recording medium is exfoliated from the image carrying body while supporting the recording medium overlapped with the image carrying body. The depressing/close-contacting unit sandwiches and depresses the recording-medium supporting member and the image carrying body in a middle position between the pressure position and the exfoliation position to closely contact the recording medium with the image carrying body.
摘要:
A method of forming an image for transferring, to a predetermined recording medium, a toner image transported to a transfer position by a toner image support for supporting the toner image and transporting the image from a predetermined toner image forming position to a predetermined toner image transfer position, wherein the method comprises the steps of:adhering a transported toner image to the recording medium, and transferring and fixing the image under heating; andusing a recording medium which has a thermoplastic light transmissive resin layer disposed on the surface of a substrate, and in which a tensile modulus of elasticity E (N/mm.sup.2) in a cross direction (CD direction) of the substrate of the recording medium and a thickness (t) mm of the substrate satisfy the following relation (1):E.multidot.t.sup.3 .gtoreq.8(N.multidot.mm)An image forming method and a recording medium used therefor can provide uniform gloss of images identical with that of the recording medium, irrespective of an image density and an image area ratio, without causing color shadow and, particularly, greatly reduce curling in the recording medium after image formation.
摘要:
Provided is an image forming method, in which image glossiness is the same as a recording medium regardless of the values of an image density or an image area percentage, especially an image excellent in not only color reproducibility but granularity is obtained and in addition, no cracks are produced in the surface layer of the recording medium after the image is formed, and a recording medium preferably used in the method.The method comprises the steps of: forming a toner image on an image carrier; placing the image formed on the image carrier on a transparent thermoplastic resin layer of a recording medium in a close contact condition, wherein the transparent thermoplastic resin layer is provided at a surface roughness (Ra) of 1.0 .mu.m or less on an opaque base of the recording medium; and heating the toner image thus placed in the close contact condition to transfer and fix the image on the transparent resin layer. The image carrier is heated to a surface temperature thereof higher than a softening point (Tmt) of a toner before the image carrier reaches a toner image transfer position and the recording medium is preferably separated from the toner image carrier when a temperature of the transparent resin of the surface of the recording medium is lower than the softening point (Tmp) by more than 10.degree. C. at a position downstream of the toner image transfer position.
摘要:
An image forming apparatus heats and presses a toner image retaining medium, with a toner image being formed thereon, and a sheet of print paper in face-contact with each other so that the toner image is transferred and simultaneously fixed onto the print paper, and rectifies the curling of the face-contact medium and paper during the heat-pressing process, thereby attaining a high print quality without creases on the paper which would otherwise emerge due to the heat-pressing process.
摘要:
The present invention provides a nitrogen-containing heterocyclic compound or a pharmaceutically acceptable salt thereof having an inhibitory effect on the production of kynurenine, represented by formula (I): (wherein R6 and R7 may be the same or different and each represent a hydrogen atom or the like, R8, R9, R19, and R11 may be the same or different and each represent a hydrogen atom or the like, R1 represents lower alkyl which may be substituted with cycloalkyl, or the like, and R3 represents optionally substituted aryl or an optionally substituted heterocyclic group).
摘要翻译:本发明提供对由式(I)表示的对犬尿胆碱的产生具有抑制作用的含氮杂环化合物或其药学上可接受的盐:(其中R 6和R 7可以相同或不同,各自表示氢原子 R 8,R 19和R 11可以相同或不同,各自表示氢原子等,R 1表示可被环烷基取代的低级烷基等,R 3表示任意取代的芳基或 任选取代的杂环基)。