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31.发明授权公开(公告)号：US07130681B2
公开(公告)日：2006-10-31
申请号：US10435174
申请日：2003-05-09
申请人： Ursula Gebhardt , Michael F. Hess
发明人： Ursula Gebhardt , Michael F. Hess
CPC分类号： A61N1/3622 , A61N1/36542
摘要： A system and method for detecting and discriminating atrial arrhythmias based on mechanical signals of cardiac wall motion and electrical signals of cardiac depolarizations. A mechanical event rate determined from sensed mechanical events is used to corroborate an electrical event rate determined from sensed EGM or ECG signals to classify the heart rhythm. If the event rates are not correlated, other parameterized data from the mechanical signal and electrical signal are evaluated to detect evidence of an arrhythmia. If electrical and mechanical event data do not corroborate a common arrhythmia condition, electrical and mechanical sensing parameters may be adjusted.
摘要翻译： 一种基于心脏壁运动和心脏去极化电信号的机械信号检测和鉴别心房心律失常的系统和方法。 使用从感测的机械事件确定的机械事件速率来确认从感测的EGM或ECG信号确定的电事件速率以分类心律。 如果事件发生率不相关，则评估来自机械信号和电信号的其他参数化数据，以检测心律失常的证据。 如果电气和机械事件数据不能证实常见的心律失常状况，则可以调整电气和机械传感参数。
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公开(公告)号：US6167307A
公开(公告)日：2000-12-26
申请号：US176570
申请日：1998-10-21
申请人： Michael F. Hess
发明人： Michael F. Hess
CPC分类号： A61N1/3627 , A61N1/3682
摘要： An AV search method and apparatus is taught with some variation. It allows a pacemaker to find the appropriate AV interval so as to avoid pacing in the ventricle when it is not necessary, even if there is intermittent AV conduction in the patient. Also, there is an adaptive PVARP method and apparatus that allows the PVARP and AV interval to be adjusted together automatically.
摘要翻译： 教学有AV变体的AV搜索方法和装置。 它允许起搏器找到适当的AV间隔，以避免在不必要的情况下在心室起搏，即使在患者中存在间歇性AV传导。 此外，还有一种自适应PVARP方法和装置，可以将PVARP和AV间隔自动调整在一起。
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公开(公告)号：US5749906A
公开(公告)日：1998-05-12
申请号：US753867
申请日：1996-12-03
申请人： Robert S. Kieval , Michael F. Hess
发明人： Robert S. Kieval , Michael F. Hess
CPC分类号： A61N1/3712 , A61N1/3627 , A61N1/3682
摘要： A dual chamber pacemaker is provided having capability for adjusting the AV escape interval so as to optimize the timing of delivered ventricular pace pulses for therapy of patients with cardiomyopathy. The pacemaker system continually monitors to determine when a delivered pace pulse results in a fusion beat, and periodically adjusts the AV escape interval in accordance with the percentage or rate of incidence of such fusion beats. In one specific embodiment, the pacing system determines the percentage of delivered ventricular pace pulses which are followed by fusion beats over a predetermined number of intervals, and decrements AV escape interval when such percentage is not below a predetermined minimum. The pacing system also periodically increments AV escape interval when the rate of fusion beats is acceptable, thereby providing a closed loop system for maintaining the AV interval at an optimally long value consistent with maximizing full capture by delivered ventricular pace pulses. In another embodiment, the V--V escape interval of a non-tracking mode pacemaker is controlled to optimize pre-excitation of the ventricle.
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34.发明授权
公开(公告)号：US5716383A
公开(公告)日：1998-02-10
申请号：US669188
申请日：1996-06-24
申请人： Robert S. Kieval , Michael F. Hess
发明人： Robert S. Kieval , Michael F. Hess
CPC分类号： A61N1/3627 , A61N1/3682
摘要： A dual chamber pacemaker is provided having capability for adjusting the AV escape interval so as to optimize the timing of delivered ventricular pace pulses for therapy of patients with cardiomyopathy. The pacemaker system continually monitors to determine when a delivered pace pulse results in a fusion beat, and periodically adjusts the AV escape interval in accordance with the percentage or rate of incidence of such fusion beats. In one specific embodiment, the pacing system determines the percentage of delivered ventricular pace pulses which are followed by fusion beats over a predetermined number of intervals, and decrements AV escape interval when such percentage is not below a predetermined minimum. The pacing system also periodically increments AV escape interval when the rate of fusion beats is acceptable, thereby providing a closed loop system for maintaining the AV interval at an optimally long value consistent with maximizing full capture by delivered ventricular pace pulses. In another embodiment, the V--V escape interval of a non-tracking mode pacemaker is controlled to optimize pre-excitation of the ventricle.
摘要翻译： 提供了一种双室起搏器，具有调整AV逃逸间隔的能力，从而优化用于治疗心肌病患者的输送心室起搏脉冲的时间。 起搏器系统持续监测以确定何时传送的步态脉冲导致融合节拍，并且根据这种融合节拍的百分比或发生率周期性地调整AV逃逸间隔。 在一个具体实施例中，起搏系统确定所提供的心室起搏脉冲的百分比，随后在预定数量的间隔上进行融合搏动，并且当该百分比不低于预定最小值时减小AV逃逸间隔。 当融合搏动速率可接受时，起搏系统还周期性地增加AV逃逸间隔，从而提供一个闭环系统，用于将AV间隔保持在最佳长度值，与通过传递的心室起搏脉冲最大化完全捕获相一致。 在另一个实施例中，控制非跟踪模式起搏器的V-V逃逸间隔以优化心室的预激发。
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35.发明授权Arrhythmia and fibrillation prevention pacemaker using ratchet up and decay modes of operation 失效心律失常和颤动预防起搏器采用棘轮和衰减手术方式
公开(公告)号：US5713929A
公开(公告)日：1998-02-03
申请号：US642717
申请日：1996-05-03
CPC分类号： A61N1/3622
摘要： New pacing algorithm defines faster than indicated pacing rate during detection of PAC's/PVC's and reduces rate after awhile to a safety rate unless natural depolarizations are detected.
摘要翻译： 新的起搏算法在PAC / PVC检测过程中定义比指定的起搏速度更快，并且在一段时间后将速率降低到安全速率，除非检测到自然去极化。
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公开(公告)号：US5676686A
公开(公告)日：1997-10-14
申请号：US637579
申请日：1996-04-25
CPC分类号： A61N1/36514 , A61N1/365
摘要： A method and apparatus for cardiac pacing, which provides for delivery of pacing pulses at an increased rate in response to a detected rapid drop in heart rate. A rapid drop may be detected in response to a drop of greater than a defined amount from the highest detected heart rate, over a preceding time period. Alternatively, an unbroken sequence of pacing pulses delivered at a base pacing rate may trigger pacing at an increased pacing rate.
摘要翻译： 一种用于心脏起搏的方法和装置，其响应于检测到的心率快速下降而以增加的速率递送起搏脉冲。 可以响应于超过先前时间段的最高检测心率的大于限定量的下降而检测到快速下降。 或者，以基本起搏速率递送的不间断的起搏脉冲序列可以以更高的起搏速率触发起搏。
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