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公开(公告)号：US20240299752A1
公开(公告)日：2024-09-12
申请号：US18610418
申请日：2024-03-20
CPC分类号： A61N1/36564 , A61N1/36578 , A61F2/2403 , A61F2/2409 , A61N1/36117 , A61N1/36521 , A61N1/36528 , A61N1/36585 , A61N1/3682
摘要： Systems and methods for controlling blood pressure via electrical stimulation of the heart are disclosed. Embodiments may include at least two different stimulation patterns, each configured to reduce blood pressure to a different degree, and may alternate between stimulation patterns based on the need of a patient, for example, alternating between day and night or between periods of strenuous and light activity. Some embodiments may take advantage of a slow baroreflex response that occurs after treatment is stopped, suspending treatment for extended periods, and then resuming treatment before blood pressure levels reach pretreatment values. Embodiments may control blood pressure by controlling atrial pressure and atrial stretch.
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公开(公告)号：US20230372716A1
公开(公告)日：2023-11-23
申请号：US18365908
申请日：2023-08-04
申请人： Medtronic, Inc.
CPC分类号： A61N1/36578 , A61N1/3756 , A61N1/37205 , A61N1/3682 , A61B5/4836 , A61B5/686 , A61B5/7282 , A61B5/1102 , A61B5/352 , A61N1/37217 , A61N1/0573
摘要： A pacemaker having a motion sensor delivers atrial-synchronized ventricular pacing by detecting events from a signal produced by the motion sensor and delivering ventricular pacing pulses at a rate that tracks the rate of the detected events. The pacemaker is configured to confirm atrial tracking of the ventricular pacing pulses by determining if detected events from the motion sensor signal are atrial events. The pacemaker is configured to adjust a control parameter used for detecting events from the motion sensor signal if atrial tracking is not confirmed.
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公开(公告)号：US11752347B2
公开(公告)日：2023-09-12
申请号：US17360648
申请日：2021-06-28
申请人： Medtronic, Inc.
发明人： Subham Ghosh
CPC分类号： A61N1/3682 , A61N1/3688 , A61N1/3706 , A61N1/37512 , A61N1/39622
摘要： The present disclosure relates generally to pacing of the cardiac conduction system of a patient, and more particularly, to providing adaptive cardiac conducting system pacing therapy and to determining selective or non-selective capture of the cardiac conduction system by cardiac conduction system pacing therapy. The adaptive cardiac conduction system pacing therapy may adjust AV delay and VV delay based on various signals and metrics and may switch between cardiac conduction system pacing therapy exclusively and cardiac conduction system pacing therapy in combination with traditional left ventricular pacing therapy.
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公开(公告)号：US11723605B2
公开(公告)日：2023-08-15
申请号：US17825786
申请日：2022-05-26
IPC分类号： A61N1/02 , A61B5/00 , A61B5/02 , A61B7/04 , A61N1/36 , A61N1/365 , A61B5/0205 , G16H50/30 , G16Z99/00 , A61B5/091 , A61N1/368 , A61N1/362
CPC分类号： A61B5/7275 , A61B5/02 , A61B5/0205 , A61B5/091 , A61B5/686 , A61B5/7282 , A61B5/746 , A61B7/04 , A61N1/3682 , A61N1/36114 , A61N1/36139 , A61N1/36585 , G16H50/30 , G16Z99/00 , A61B5/4848 , A61N1/3627
摘要： Systems and methods are described for subject rehospitalization management. In an example, multiple physiologic signals can be obtained from a subject using multiple sensors. In response to a hospitalization event, pre-hospitalization characteristics of the multiple physiologic signals can be identified. Post-hospitalization characteristics of the multiple physiologic signals can be identified, including characteristics that differ from their corresponding pre-hospitalization characteristics. Later subsequent physiologic signals can be further monitored after the hospitalization event, such as using the same multiple sensors, and subsequent physiologic signal characteristics can be identified. In an example, a heart failure diagnostic indication can be determined using information about the pre-hospitalization characteristics, the post-hospitalization characteristics, and the subsequent characteristics. Information about relative changes in signal characteristics from multiple sensors can be used to identify particular subject physiologic signals to monitor during subsequent periods.
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公开(公告)号：US11717691B2
公开(公告)日：2023-08-08
申请号：US17393647
申请日：2021-08-04
申请人： Pacesetter, Inc.
发明人： Xiaoyi Min
CPC分类号： A61N1/3756 , A61N1/3627 , A61N1/3682 , A61N1/3684 , A61N1/36592 , A61B5/352 , A61N1/056 , A61N1/3622 , A61N1/36542 , A61N1/3962
摘要： Cardiac pacing is performed using leadless pacemakers (LPs). An AV delay is determined based on a P-wave duration. When pacing occurs during cardiac cycles starting with intrinsic atrial events, the AV delay is set to the P-wave duration plus a first offset if the P-wave duration is greater than a first threshold duration, and the AV delay is set to the P-wave duration plus a second offset that is greater than the first offset, if the P-wave duration is less than the first threshold duration. When pacing occurs during cardiac cycles starting with paced atrial events, the AV delay is set to the P-wave duration plus a third offset, if the P-wave duration is greater than a second threshold duration, or is set to the P-wave duration plus a fourth offset that is greater than the third offset, if the P-wave duration is less than the second threshold duration.
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公开(公告)号：US11712567B2
公开(公告)日：2023-08-01
申请号：US17205114
申请日：2021-03-18
CPC分类号： A61N1/36564 , A61F2/2412 , A61F2/2424 , A61N1/3682 , A61N1/3684 , A61N1/36117 , A61N1/36514 , A61N1/36528 , A61N1/36571 , A61N1/36578 , A61N1/36585 , A61F2250/0013 , A61N1/36842 , A61N1/36843
摘要： Systems and methods for controlling blood pressure by controlling atrial pressure and atrial stretch are disclosed. In some embodiments, a stimulation circuit may be configured to deliver a stimulation pulse to at least one cardiac chamber of a heart of a patient, and at least one controller may be configured to execute delivery of one or more stimulation patterns of stimulation pulses to the at least one cardiac chamber, wherein at least one of the stimulation pulses stimulates the heart such that an atrial pressure resulting from atrial contraction of an atrium overlaps in time a passive pressure build-up of the atrium, such that an atrial pressure of the atrium resulting from the stimulation is a combination of the atrial pressure resulting from atrial contraction and the passive pressure build-up and is higher than an atrial pressure of the atrium would be without the stimulation, and such that the blood pressure of the patient is reduced.
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公开(公告)号：US20230149717A1
公开(公告)日：2023-05-18
申请号：US17920536
申请日：2021-04-16
发明人： Thomas Doerr , Ingo Weiss , Ulrich Busch
CPC分类号： A61N1/3627 , A61N1/3682 , A61N1/3684
摘要： An implantable device for stimulating a heart to lower blood pressure, comprising: a stimulation unit configured to stimulate a ventricle, and a sensing unit for detecting atrial activity of the heart, wherein the stimulation unit is configured to stimulate the ventricle for at least one cardiac cycle with a predefined delay after detection of an atrial activity or to not stimulate the ventricle for at least one cardiac cycle.
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公开(公告)号：US20190151666A1
公开(公告)日：2019-05-23
申请号：US16198872
申请日：2018-11-22
申请人： CAIRDAC
发明人： Jean-Luc Bonnet
CPC分类号： A61N1/3785 , A61B5/686 , A61B5/6869 , A61N1/025 , A61N1/36507 , A61N1/3682 , A61N1/3684 , A61N1/37512 , A61N1/37518 , A61N1/3756 , A61N1/3956 , H01L41/1136 , H02N2/186
摘要： An energy harvester converts into electrical energy the external stresses applied to the implant at the heartbeat rhythm. This harvester includes an inertial unit and a transducer delivering an oscillating electrical signal that is rectified and regulated for powering the implant and charging an energy storage component. The instantaneous variations of this electrical signal are analyzed in a detection window following or preceding a ventricular contraction, to obtain atrial activity information representative of the atrium contribution to the electric signal, in particular information about the presence/absence of a spontaneous atrial contraction, and/or parameters making it possible to determine an atrioventricular delay to be applied if the ventricle has to be stimulated.
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公开(公告)号：US20180326215A1
公开(公告)日：2018-11-15
申请号：US15975258
申请日：2018-05-09
申请人： Medtronic, Inc.
发明人： Subham GHOSH
CPC分类号： A61N1/3682 , A61N1/0504 , A61N1/0563 , A61N1/057 , A61N1/3621 , A61N1/365 , A61N1/36585 , A61N1/36592 , A61N1/36843 , A61N1/3688 , A61N1/3702 , A61N1/371 , A61N1/3756 , A61N1/3962 , A61N1/39622
摘要： Methods and/or devices may be configured to estimate right ventricular-timings from left ventricular (LV) sensing times for adaptive cardiac therapy using DDD/VDD LV pacing without using a right ventricular (RV) lead. One embodiment employs a subcutaneous device (SD) in a patient and a leadless pacing device (LPD) coupled to a patient's heart. Heart activity including atrial and ventricular events are sensed from the patient's heart using the SD. Left ventricular events (LVS) are sensed using the LPD. The SD is used to determine whether cardiac resynchronization pacing therapy (CRT pacing) is appropriate based upon the heart activity sensed by the SD. The SD is further configured to determine timing of CRT pacing pulses for delivery to cardiac tissue through the LPD.
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公开(公告)号：US20180280695A1
公开(公告)日：2018-10-04
申请号：US15474950
申请日：2017-03-30
申请人： NewStim, Inc.
CPC分类号： A61N1/3627 , A61B5/04012 , A61B5/042 , A61B5/0422 , A61B5/0432 , A61B5/044 , A61B5/0452 , A61B5/04525 , A61B5/046 , A61B5/0464 , A61B5/0472 , A61B5/4836 , A61N1/3622 , A61N1/36507 , A61N1/3682 , A61N1/3684
摘要： Brugada syndrome and related forms of ion channelopathies, including ventricular asynchrony of contraction, originate in the region near the His bundle or para-Hisian regions of the heart. Manifestations of Brugada syndrome can be corrected by delivering endocardial electrical stimulation coincident to the activation wave front propagated from the atrioventricular (AV) node. By performing the start of the activation of the HIS bundle or para-Hisian region early enough, electrical stimulation can be delivered fast enough to compensate for the conduction problems that start in those region, such that the activation wave front, as stimulated, transitions from the AV node to the His bundle in a normal, albeit electrically-supplemented, fashion. This stimulation not only helps resolve the conditions that trigger Brugada syndrome, but also resolves the asynchrony of the contraction of the heart.
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