公开(公告)号：US20080077006A1

公开(公告)日：2008-03-27

申请号：US11573897

申请日：2005-08-19

申请人： Ulrich Katscher ,  Hannes Dahnke

发明人： Ulrich Katscher ,  Hannes Dahnke

IPC分类号： A61B5/055

CPC分类号： G01R33/50 ,  G01R33/58

摘要： The invention relates to an MR method of determining local relaxation time values (T1, T2) of an examination object (5). Firstly, two or more MR images (3, 4) of the examination object (5) are recorded, each with different time parameter sets (TR1, TE1, TR2, TE2) of an imaging sequence. MR images (6, 7) of a phantom are likewise recorded, wherein the same time parameter sets (TR1, TE1, TR2, TE2) of the imaging sequence are used and wherein the phantom has a known spatial distribution of relaxation time values (T1, T2). The local relaxation time values (T1, T2) of the examination object (5) are determined by comparing image values of the MR images (3, 4) of the examination object (5) with image values of the MR images (6, 7) of the phantom and by assigning image values of the MR images of the phantom to relaxation time values (T1, T2) according to the known spatial distribution of relaxation time values (T1, T2) of the phantom.

摘要翻译： 本发明涉及一种用于确定检查对象（5）的局部弛豫时间值（T 1，T 2> 2）的MR方法。 首先，记录检查对象（5）的两个或更多个MR图像（3,4），每个具有不同的时间参数组（TR <1> 1，TE 1，TR 2/2，TE 2 2）。 同样地记录了体模的MR图像（6,7），其中相同的时间参数组（TR＆lt; 1＆gt;，TE＆lt; 1＆gt;，TR＆lt; 2＆ ，TE 2 2），并且其中，所述体模具有已知的弛豫时间值的空间分布（T 1，T 2，N 2， ）。 通过比较检查对象（5）的MR图像（3,4）的图像值来确定检查对象（5）的局部弛豫时间值（T 1，T 2，2） 检查对象（5），其具有所述体模的MR图像（6,7）的图像值，并且通过将所述体模的MR图像的图像值分配给弛豫时间值（T 1>，T

公开(公告)号：US07123007B2

公开(公告)日：2006-10-17

申请号：US09995439

申请日：2001-11-27

申请人： Ulrich Katscher ,  Johannes Jacobus Van Vaals

发明人： Ulrich Katscher ,  Johannes Jacobus Van Vaals

IPC分类号： G01V3/00

CPC分类号： G01R33/5611 ,  G01R33/4835 ,  G01R33/56509

摘要： The invention relates to an MR imaging method in which the parallel acquisition of the MR data, for example in conformity with the SMASH or SENSE methods, is performed by means of a plurality of receiving coils. The different spatial sensitivity profiles of the receiving coils are used for the image reconstruction. When the sensitivity data used during the image reconstruction do not correspond to the position in space of the receiving coils during the image acquisition, undesirable image artifacts will occur. In accordance with the invention such artifacts are eliminated by (virtually) adapting the spatial sensitivity profiles automatically during the image reconstruction.

公开(公告)号：US20060013459A1

公开(公告)日：2006-01-19

申请号：US10510005

申请日：2003-03-24

申请人： Ulrich Katscher ,  Thomas Koehler ,  Thomas Schmidt

发明人： Ulrich Katscher ,  Thomas Koehler ,  Thomas Schmidt

IPC分类号： G06K9/00

CPC分类号： A61B6/032 ,  A61B5/055 ,  A61B6/037 ,  A61B6/5235 ,  A61B6/5247 ,  G01R33/481 ,  G06T11/005

摘要： The invention relates to a method for the selective imaging of body structures, in which method—a first image data set is acquired by means of a first tomography method,—a second image data set is acquired by means of a second tomography method which has a resolution which is higher than that of the first method, the image data of the first and the second image data set coinciding at least partly in space,—an image is reconstructed from the first image data set, and—the image data to be imaged is selected from the first image data set by means of the second image data set. In order to achieve a higher imaging quality while using a low-resolution tomography method, in accordance with the invention it is proposed that for the image reconstruction from the first image data set—first at least one image region to be imaged is selected from the second image data set, and—subsequently the image reconstruction is calculated from the image data of the first image data set which are situated in the selected image region.

摘要翻译： 本发明涉及一种用于身体结构选择性成像的方法，其中通过第一层析成像方法获取第一图像数据集，通过第二层析成像方法获得第二图像数据集， 分辨率高于第一方法的分辨率，第一和第二图像数据组的图像数据至少部分地在空间中重合， - 从第一图像数据集重建图像，并且将图像数据设置为 通过第二图像数据集从第一图像数据集中选择成像。 为了在使用低分辨率断层摄影方法时获得更高的成像质量，根据本发明，提出了对于从第一图像数据集进行的图像重建，首先从至少一个要成像的图像区域中选择要成像的图像区域 第二图像数据组，并且随后根据位于所选择的图像区域中的第一图像数据组的图像数据计算图像重建。

公开(公告)号：US09638777B2

公开(公告)日：2017-05-02

申请号：US13522367

申请日：2011-01-13

申请人： Tobias Ratko Voigt ,  Ulrich Katscher ,  Thomas Hendrik Rozijn ,  Paul Royston Harvey ,  Hanno Homann ,  Christian Findeklee ,  Eberhard Sebastian Hansis

发明人： Tobias Ratko Voigt ,  Ulrich Katscher ,  Thomas Hendrik Rozijn ,  Paul Royston Harvey ,  Hanno Homann ,  Christian Findeklee ,  Eberhard Sebastian Hansis

IPC分类号： G01R33/54 ,  G01R33/341 ,  G01R33/48 ,  A61B5/053 ,  A61B5/055 ,  G01R33/24 ,  G01R33/44

CPC分类号： G01R33/48 ,  A61B5/0536 ,  A61B5/055 ,  G01R33/246 ,  G01R33/443

摘要： A magnetic resonance method of electric properties tomography imaging of an object includes applying an excitation RF field to the object via a coil at a first spatial coil position (402), acquiring resulting magnetic resonance signals via a receiving channel from the object, determining from the acquired magnetic resonance signals a first phase distribution and a first amplitude of a given magnetic field component of the excitation RF field of the coil at the first coil position (402), repeating these steps with a coil at a second different spatial coil position (404), to obtain a second phase distribution, determining a phase difference between the first and second phase distribution, determining a first and a second complex permittivity of the object, the first complex permittivity comprising the first amplitude of the given magnetic field component and the second complex permittivity comprising the second amplitude of the given magnetic field component and the phase difference, equating the first complex permittivity and the second complex permittivity for receiving a final equation and determining from the final equation a phase of the given magnetic field component for the first coil position (402).

公开(公告)号：US08941380B2

公开(公告)日：2015-01-27

申请号：US12936540

申请日：2009-04-13

申请人： Ingmar Graesslin ,  Sven Biederer ,  Ulrich Katscher ,  Ferdinand Schweser ,  Peter Boernert ,  Paul Royston Harvey ,  Wilhelmus Reinerius Maria Mens

发明人： Ingmar Graesslin ,  Sven Biederer ,  Ulrich Katscher ,  Ferdinand Schweser ,  Peter Boernert ,  Paul Royston Harvey ,  Wilhelmus Reinerius Maria Mens

IPC分类号： G01R33/44 ,  G01R33/58 ,  G01R33/561 ,  G01R33/28 ,  G01R33/565

CPC分类号： G01R33/583 ,  G01R33/288 ,  G01R33/5612 ,  G01R33/5659

摘要： In a method and apparatus to enable increased RF duty cycle in high field MR scans, a specific energy absorption rate (SAR) calculation processor calculates the local and global SAR or even a spatial SAR map. By incorporating additional information as, e.g. patient position, the SAR calculation accuracy can be increased as well as by using more patient specific pre-calculated information (e.g. based on different bio meshes), the so called Q-matrices. A sequence controller maybe provided to create a global SAR optimal RF pulse. After the optimal RF pulse is applied, the SAR and its spatial distribution are determined. SAR hotspots are also determined. Q-matrices within an appropriate radius around the hotspots are averaged and added to a global Q-matrix in a weighted fashion. After the global Q-matrix is updated, a new optimal RF pulse is created.

摘要翻译： 在能够在高场MR扫描中增加RF占空比的方法和装置中，比能量吸收率（SAR）计算处理器计算局部和全局SAR或甚至空间SAR图。 通过引入附加信息，例如。 患者位置，SAR计算精度以及通过使用更多患者特定的预先计算的信息（例如，基于不同的生物网格），即所谓的Q矩阵。 可以提供序列控制器以创建全局SAR最优RF脉冲。 在施加最佳RF脉冲之后，确定SAR及其空间分布。 SAR热点也是决定的。 在热点周围的适当半径内的Q矩阵被平均，并以加权的方式加到全局Q矩阵上。 在更新全局Q矩阵之后，创建一个新的最优RF脉冲。

公开(公告)号：US08812078B2

公开(公告)日：2014-08-19

申请号：US13388108

申请日：2010-08-02

申请人： Peter Vernickel ,  Ulrich Katscher ,  Bernhard Gleich ,  Jurgen Erwin Rahmer

发明人： Peter Vernickel ,  Ulrich Katscher ,  Bernhard Gleich ,  Jurgen Erwin Rahmer

IPC分类号： A61B5/05 ,  G01V3/00

CPC分类号： A61B5/05 ,  A61B5/0515 ,  A61B5/7221 ,  A61B2562/0223

摘要： The present invention relates to an apparatus (100) for determining at least one electromagnetic quantity characterizing an electromagnetic property of an object, in particular a human body, wherein said object contains magnetic particles. The apparatus (100) applying the known principle of Magnetic Particle Imaging (MPI) comprises selection means for generating a magnetic selection field (50) having the known field pattern showing a field free point (FFP), drive means for changing the position in space of the FFP by means of a magnetic drive field, receiving means for acquiring detection signals depending on the magnetization of the magnetic particles within a field of view (28) and a reconstruction unit (152) for reconstructing a particle distribution quantity depending on the detection signals. The apparatus (100) further comprises a control unit (150) for controlling the receiving means for acquiring a first set of detection signals corresponding to a first drive field frequency and a second set of detection signals corresponding to a second drive field frequency, with both drive field frequencies differing from each other. The control unit (15) further controls the reconstruction unit (152) for reconstructing a first particle distribution quantity depending on the first set of detection signals and a second particle distribution quantity depending on the second set of detection signals. The apparatus (100) further comprises a determination unit (160) for determining the electromagnetic quantity depending on the first and second particle distribution quantity. The present invention further relates to a corresponding method as well as to a computer program.

摘要翻译： 本发明涉及一种用于确定表征物体特别是人体的电磁特性的至少一个电磁量的装置（100），其中所述物体包含磁性颗粒。 应用已知的磁性粒子成像原理（MPI）的装置（100）包括选择装置，用于产生具有示出场自由点（FFP）的已知场模式的磁选择场（50），用于改变空间位置的驱动装置 通过磁驱动场的FFP的接收装置，用于根据视场内的磁性粒子的磁化获取检测信号的接收装置（28）和用于根据检测重建粒子分布量的重建单元（152） 信号。 该设备（100）还包括控制单元（150），用于控制接收装置，用于获取对应于第一驱动场频率的第一组检测信号和对应于第二驱动场频率的第二组检测信号，两者 驱动场频率彼此不同。 控制单元（15）进一步控制重建单元（152），用于根据第一组检测信号重建第一粒子分布量，并根据第二组检测信号控制第二粒子分布量。 所述设备（100）还包括用于根据第一和第二粒子分布量来确定电磁量的确定单元（160）。 本发明还涉及相应的方法以及计算机程序。

公开(公告)号：US08698495B2

公开(公告)日：2014-04-15

申请号：US12933897

申请日：2009-03-26

申请人： Kay Nehrke ,  Peter Boernert ,  Tobias Ratko Voigt ,  Ulrich Katscher

发明人： Kay Nehrke ,  Peter Boernert ,  Tobias Ratko Voigt ,  Ulrich Katscher

IPC分类号： G01V3/00

CPC分类号： G01R33/586 ,  G01R33/246 ,  G01R33/3415 ,  G01R33/5612 ,  G01R33/56518 ,  G01R33/5659

摘要： A magnetic resonance method includes performing a plurality of magnetic resonance excitation operations each using a different sub-set of a set of radio frequency transmit coils (30), each sub-set including more than one radio frequency transmit coil, acquiring magnetic resonance data responsive to each said magnetic resonance excitation operation, and computing a B1 or flip angle map for each radio frequency transmit coil of the set of radio frequency transmit coils based on the acquired magnetic resonance data. A magnetic resonance method includes performing an actual flip angle mapping (AFI) sequence using a radio frequency transmit coil (32) with a ratio TR1:TR2 of the TR times of the AFI sequence selected to be rational, acquiring magnetic resonance data responsive to said AFI sequence, and computing a B1 or flip angle map for the radio frequency transmit coil based on the acquired magnetic resonance data.

摘要翻译： 磁共振方法包括使用一组射频发射线圈（30）的不同子集执行多个磁共振激励操作，每个子集包括多于一个射频发射线圈，响应于磁共振数据 到每个所述磁共振激励操作，以及基于所获取的磁共振数据计算所述射频发射线圈组中的每个射频发射线圈的B1或翻角图。 磁共振方法包括使用射频发射线圈（32）执行实际的翻转角映射（AFI）序列，其中AFI序列的TR次的比值TR1：TR2被选择为合理，获取响应于所述的 AFI序列，并且基于获取的磁共振数据计算用于射频发射线圈的B1或翻转角图。

公开(公告)号：US20110163749A1

公开(公告)日：2011-07-07

申请号：US13063477

申请日：2009-09-15

申请人： Ulrich Katscher ,  Ingmar Graesslin

发明人： Ulrich Katscher ,  Ingmar Graesslin

IPC分类号： G01R33/44

CPC分类号： G01R33/3415 ,  G01R33/288 ,  G01R33/5612 ,  G01R33/5659

摘要： A magnetic resonance system comprises: a magnetic resonance scanner (12) including a multi-channel RF transmit system (32, 34); an RF shimming processor (50) configured to compute complex amplitude values for operative channels of the multi-channel RF transmit system based on a figure-of-merit (70) comprising a weighted combination of a B1 uniformity measure and a total power measure; and an RF transmit sub-system (30) configured to drive the multi-channel RF transmit system to excite magnetic resonance using the complex amplitude values computed by the RF shimming processor for the operative channels of the multi-channel RF transmit system.

摘要翻译： 磁共振系统包括：包括多通道RF发射系统（32,34）的磁共振扫描仪（12）; RF匀场处理器（50），被配置为基于包括B1均匀度测量和总功率测量的加权组合的品质因数（70）来计算所述多通道RF发射系统的操作信道的复振幅值; 以及RF发射子系统（30），其被配置为使用由所述RF匀场处理器为所述多声道RF发射系统的操作信道计算的复振幅值来驱动所述多声道RF发射系统来激励磁共振。

公开(公告)号：US20100136929A1

公开(公告)日：2010-06-03

申请号：US12598448

申请日：2008-04-25

申请人： Peter Vernickel ,  Ulrich Katscher

发明人： Peter Vernickel ,  Ulrich Katscher

IPC分类号： H04B1/02

CPC分类号： G01R33/5612 ,  G01R33/246 ,  G01R33/34076 ,  G01R33/3415 ,  G01R33/3678

摘要： A multi-channel RF transmitter arrangement in the form of, or comprising, a plurality RF antennas, antenna elements, coils or coil elements (11 to 16), for generating an RF field, especially for use in a magnetic resonance imaging (MRI) system for exciting nuclear magnetic resonances (NMR), and a method for generating such an RF field is disclosed. Furthermore, a multi-channel RF transmit system comprising a plurality of RF waveform generators (31, 32, . . . 3n) and RF amplifiers (21, 22, . . . 2n) for generating RF transmit signals for feeding such a multi-channel RF transmitter arrangement, especially for use as an RF excitation system in an MRI system is disclosed.

摘要翻译： 天线元件，线圈或线圈元件（11至16）形式的或包括多个RF天线的多通道RF发射器装置，用于产生RF场，特别是用于磁共振成像（MRI） 公开了用于激发核磁共振（NMR）的系统，以及用于产生这种RF场的方法。 此外，包括多个RF波形发生器（31,32 ...，3n）和RF放大器（21,22 ...，2n）的多通道RF发射系统，用于产生RF发射信号， 公开了一种特别用作MRI系统中的RF激励系统的射频发射机布置。

公开(公告)号：US07701211B2

公开(公告)日：2010-04-20

申请号：US11721544

申请日：2005-12-19

申请人： Ulrich Katscher ,  Christian Findeklee ,  Peter Vernickel ,  Christoph Leussler

发明人： Ulrich Katscher ,  Christian Findeklee ,  Peter Vernickel ,  Christoph Leussler

IPC分类号： G01V3/00

CPC分类号： G01R33/3607 ,  G01R33/5611

摘要： The present invention relates to a magnetic resonance imaging system (1) comprising a plurality of RF coils (4) forming a multi-coil array and furthermore to a magnetic resonance imaging method for such a system. In order to provide an MR imaging system and method in which a desired excitation pattern is achieved in a simple way, it is suggested to utilize an analytical procedure how to combine the single coil elements to obtain the most homogeneous B1 excitation possible with a given coil array. In other words, the homogeneity of the B1 field is improved in a very simple way. The sensitivity of each RF coil (4) of the coil array is scaled or weighted by a complex factor, i.e. phase and amplitude of each coil drive signal is adjusted accordingly. These complex factors are determined analytically utilizing the sensitivities S(8) of the coil elements (4) and the desired excitation pattern P (IO, 11). The invention allows an optimized control of the field distribution (RF shimming) for arbitrary RF coil arrays. With the invention a fast and easy independent phase and amplitude control of the coil elements (4) is provided for reducing body-induced RF non-uniformities, which appear in high field MR systems.

摘要翻译： 本发明涉及包括形成多线圈阵列的多个RF线圈（4）以及此类系统的磁共振成像方法的磁共振成像系统（1）。 为了提供以简单的方式实现期望的激励模式的MR成像系统和方法，建议使用分析程序如何组合单个线圈元件以获得可用于给定线圈的最均匀的B1激励 数组。 换句话说，B1场的均匀性以非常简单的方式得到改善。 线圈阵列的每个RF线圈（4）的灵敏度被复合因子缩放或加权，即相应地调整每个线圈驱动信号的相位和幅度。 利用线圈元件（4）的灵敏度S（8）和期望的激励模式P（IO，11）来分析地确定这些复杂因素。 本发明允许对任意RF线圈阵列的场分布（RF匀场）的优化控制。 利用本发明，提供线圈元件（4）的快速且容易的独立相位和幅度控制，用于减少出现在高场MR系统中的体引起的RF不均匀性。