公开(公告)号：US20120126800A1

公开(公告)日：2012-05-24

申请号：US13388108

申请日：2010-08-02

申请人： Peter Vernickel ,  Ulrich Katscher ,  Bernhard Gleich ,  Jurgen Erwin Rahmer

发明人： Peter Vernickel ,  Ulrich Katscher ,  Bernhard Gleich ,  Jurgen Erwin Rahmer

IPC分类号： G01N27/72

CPC分类号： A61B5/05 ,  A61B5/0515 ,  A61B5/7221 ,  A61B2562/0223

摘要： The present invention relates to an apparatus (100) for determining at least one electromagnetic quantity characterizing an electromagnetic property of an object, in particular a human body, wherein said object contains magnetic particles. The apparatus (100) applying the known principle of Magnetic Particle Imaging (MPI) comprises selection means for generating a magnetic selection field (50) having the known field pattern showing a field free point (FFP), drive means for changing the position in space of the FFP by means of a magnetic drive field, receiving means for acquiring detection signals depending on the magnetization of the magnetic particles within a field of view (28) and a reconstruction unit (152) for reconstructing a particle distribution quantity depending on the detection signals. The apparatus (100) further comprises a control unit (150) for controlling the receiving means for acquiring a first set of detection signals corresponding to a first drive field frequency and a second set of detection signals corresponding to a second drive field frequency, with both drive field frequencies differing from each other. The control unit (15) further controls the reconstruction unit (152) for reconstructing a first particle distribution quantity depending on the first set of detection signals and a second particle distribution quantity depending on the second set of detection signals. The apparatus (100) further comprises a determination unit (160) for determining the electromagnetic quantity depending on the first and second particle distribution quantity. The present invention further relates to a corresponding method as well as to a computer program.

摘要翻译： 本发明涉及一种用于确定表征物体特别是人体的电磁特性的至少一个电磁量的装置（100），其中所述物体包含磁性颗粒。 应用已知的磁性粒子成像原理（MPI）的装置（100）包括选择装置，用于产生具有示出场自由点（FFP）的已知场模式的磁选择场（50），用于改变空间位置的驱动装置 通过磁驱动场的FFP的接收装置，用于根据视场内的磁性粒子的磁化获取检测信号的接收装置（28）和用于根据检测重建粒子分布量的重建单元（152） 信号。 该设备（100）还包括控制单元（150），用于控制接收装置，用于获取对应于第一驱动场频率的第一组检测信号和对应于第二驱动场频率的第二组检测信号，两者 驱动场频率彼此不同。 控制单元（15）进一步控制重建单元（152），用于根据第一组检测信号重建第一粒子分布量，并根据第二组检测信号控制第二粒子分布量。 所述设备（100）还包括用于根据第一和第二粒子分布量来确定电磁量的确定单元（160）。 本发明还涉及相应的方法以及计算机程序。

公开(公告)号：US20110133729A1

公开(公告)日：2011-06-09

申请号：US13058547

申请日：2009-08-07

申请人： Peter Vernickel ,  Peter Mazurkewitz ,  Daniel Wirtz ,  Christoph Leussler ,  Ulrich Katscher

发明人： Peter Vernickel ,  Peter Mazurkewitz ,  Daniel Wirtz ,  Christoph Leussler ,  Ulrich Katscher

IPC分类号： G01R33/14

CPC分类号： A61B5/0536 ,  A61B5/0522

摘要： A method and a monitoring device for performing an RF-safe MIT scan is disclosed in which it is prevented that an RF exposure, especially a specific absorption rate (SAR), imposed on an examination object, especially a patient, exceeds certain limit values during a magnetic induction tomography (MIT) scan. This is achieved on the one hand by an RF simulation method for simulating intended MIT operating parameters and calculating a resulting RF exposure of the object, and on the other hand by a monitoring device for monitoring the RF power which is applied to the object.

摘要翻译： 公开了用于执行RF安全MIT扫描的方法和监视装置，其中防止施加在检查对象，特别是患者上的RF暴露，特别是特定吸收率（SAR）超过某些限制值 磁感应断层扫描（MIT）扫描。 这一方面通过用于模拟预期的MIT操作参数并计算所得到的对象的RF曝光的RF模拟方法，另一方面由用于监视施加到对象的RF功率的监视装置来实现。

公开(公告)号：US07653228B2

公开(公告)日：2010-01-26

申请号：US10510005

申请日：2003-03-24

申请人： Ulrich Katscher ,  Thomas Koehler ,  Thomas Schmidt

发明人： Ulrich Katscher ,  Thomas Koehler ,  Thomas Schmidt

IPC分类号： G06K9/00

CPC分类号： A61B6/032 ,  A61B5/055 ,  A61B6/037 ,  A61B6/5235 ,  A61B6/5247 ,  G01R33/481 ,  G06T11/005

摘要： A method for selective imaging of body structures includes acquiring first image data set by a first tomography method, acquiring a second image data set by a second tomography method which has a resolution which is higher than that of the first method, the image data of the first and the second image data set coinciding at least partly in space, reconstructing an image from the first image data set, and selecting the image data to be reconstructed from the first image data set using the second image data set. In order to achieve a higher imaging quality while using a low-resolution tomography method, image reconstruction of the image data selected from the first image data set at least one image region to be imaged is selected from the second image data set, and subsequently the image reconstruction is calculated from the image data of the first image data set which are situated in the selected image region.

摘要翻译： 一种用于身体结构的选择性成像的方法包括获取通过第一层析成像方法设置的第一图像数据，通过具有比第一方法的分辨率高的分辨率的第二断层摄影方法获取第二图像数据集， 第一和第二图像数据集合至少部分地在空间中重合，从第一图像数据集重建图像，以及使用第二图像数据集从第一图像数据集中选择要重建的图像数据。 为了在使用低分辨率断层摄影方法时获得更高的成像质量，从第二图像数据集中选择从要成像的至少一个图像区域的第一图像数据中选择的图像数据的图像重建，随后 从位于所选择的图像区域中的第一图像数据组的图像数据计算图像重建。

公开(公告)号：US20080077006A1

公开(公告)日：2008-03-27

申请号：US11573897

申请日：2005-08-19

申请人： Ulrich Katscher ,  Hannes Dahnke

发明人： Ulrich Katscher ,  Hannes Dahnke

IPC分类号： A61B5/055

CPC分类号： G01R33/50 ,  G01R33/58

摘要： The invention relates to an MR method of determining local relaxation time values (T1, T2) of an examination object (5). Firstly, two or more MR images (3, 4) of the examination object (5) are recorded, each with different time parameter sets (TR1, TE1, TR2, TE2) of an imaging sequence. MR images (6, 7) of a phantom are likewise recorded, wherein the same time parameter sets (TR1, TE1, TR2, TE2) of the imaging sequence are used and wherein the phantom has a known spatial distribution of relaxation time values (T1, T2). The local relaxation time values (T1, T2) of the examination object (5) are determined by comparing image values of the MR images (3, 4) of the examination object (5) with image values of the MR images (6, 7) of the phantom and by assigning image values of the MR images of the phantom to relaxation time values (T1, T2) according to the known spatial distribution of relaxation time values (T1, T2) of the phantom.

摘要翻译： 本发明涉及一种用于确定检查对象（5）的局部弛豫时间值（T 1，T 2> 2）的MR方法。 首先，记录检查对象（5）的两个或更多个MR图像（3,4），每个具有不同的时间参数组（TR <1> 1，TE 1，TR 2/2，TE 2 2）。 同样地记录了体模的MR图像（6,7），其中相同的时间参数组（TR＆lt; 1＆gt;，TE＆lt; 1＆gt;，TR＆lt; 2＆ ，TE 2 2），并且其中，所述体模具有已知的弛豫时间值的空间分布（T 1，T 2，N 2， ）。 通过比较检查对象（5）的MR图像（3,4）的图像值来确定检查对象（5）的局部弛豫时间值（T 1，T 2，2） 检查对象（5），其具有所述体模的MR图像（6,7）的图像值，并且通过将所述体模的MR图像的图像值分配给弛豫时间值（T 1>，T

公开(公告)号：US07123007B2

公开(公告)日：2006-10-17

申请号：US09995439

申请日：2001-11-27

申请人： Ulrich Katscher ,  Johannes Jacobus Van Vaals

发明人： Ulrich Katscher ,  Johannes Jacobus Van Vaals

IPC分类号： G01V3/00

CPC分类号： G01R33/5611 ,  G01R33/4835 ,  G01R33/56509

摘要： The invention relates to an MR imaging method in which the parallel acquisition of the MR data, for example in conformity with the SMASH or SENSE methods, is performed by means of a plurality of receiving coils. The different spatial sensitivity profiles of the receiving coils are used for the image reconstruction. When the sensitivity data used during the image reconstruction do not correspond to the position in space of the receiving coils during the image acquisition, undesirable image artifacts will occur. In accordance with the invention such artifacts are eliminated by (virtually) adapting the spatial sensitivity profiles automatically during the image reconstruction.

公开(公告)号：US20060013459A1

公开(公告)日：2006-01-19

申请号：US10510005

申请日：2003-03-24

申请人： Ulrich Katscher ,  Thomas Koehler ,  Thomas Schmidt

发明人： Ulrich Katscher ,  Thomas Koehler ,  Thomas Schmidt

IPC分类号： G06K9/00

CPC分类号： A61B6/032 ,  A61B5/055 ,  A61B6/037 ,  A61B6/5235 ,  A61B6/5247 ,  G01R33/481 ,  G06T11/005

摘要： The invention relates to a method for the selective imaging of body structures, in which method—a first image data set is acquired by means of a first tomography method,—a second image data set is acquired by means of a second tomography method which has a resolution which is higher than that of the first method, the image data of the first and the second image data set coinciding at least partly in space,—an image is reconstructed from the first image data set, and—the image data to be imaged is selected from the first image data set by means of the second image data set. In order to achieve a higher imaging quality while using a low-resolution tomography method, in accordance with the invention it is proposed that for the image reconstruction from the first image data set—first at least one image region to be imaged is selected from the second image data set, and—subsequently the image reconstruction is calculated from the image data of the first image data set which are situated in the selected image region.

摘要翻译： 本发明涉及一种用于身体结构选择性成像的方法，其中通过第一层析成像方法获取第一图像数据集，通过第二层析成像方法获得第二图像数据集， 分辨率高于第一方法的分辨率，第一和第二图像数据组的图像数据至少部分地在空间中重合， - 从第一图像数据集重建图像，并且将图像数据设置为 通过第二图像数据集从第一图像数据集中选择成像。 为了在使用低分辨率断层摄影方法时获得更高的成像质量，根据本发明，提出了对于从第一图像数据集进行的图像重建，首先从至少一个要成像的图像区域中选择要成像的图像区域 第二图像数据组，并且随后根据位于所选择的图像区域中的第一图像数据组的图像数据计算图像重建。

公开(公告)号：US08812078B2

公开(公告)日：2014-08-19

申请号：US13388108

申请日：2010-08-02

申请人： Peter Vernickel ,  Ulrich Katscher ,  Bernhard Gleich ,  Jurgen Erwin Rahmer

发明人： Peter Vernickel ,  Ulrich Katscher ,  Bernhard Gleich ,  Jurgen Erwin Rahmer

IPC分类号： A61B5/05 ,  G01V3/00

CPC分类号： A61B5/05 ,  A61B5/0515 ,  A61B5/7221 ,  A61B2562/0223

摘要： The present invention relates to an apparatus (100) for determining at least one electromagnetic quantity characterizing an electromagnetic property of an object, in particular a human body, wherein said object contains magnetic particles. The apparatus (100) applying the known principle of Magnetic Particle Imaging (MPI) comprises selection means for generating a magnetic selection field (50) having the known field pattern showing a field free point (FFP), drive means for changing the position in space of the FFP by means of a magnetic drive field, receiving means for acquiring detection signals depending on the magnetization of the magnetic particles within a field of view (28) and a reconstruction unit (152) for reconstructing a particle distribution quantity depending on the detection signals. The apparatus (100) further comprises a control unit (150) for controlling the receiving means for acquiring a first set of detection signals corresponding to a first drive field frequency and a second set of detection signals corresponding to a second drive field frequency, with both drive field frequencies differing from each other. The control unit (15) further controls the reconstruction unit (152) for reconstructing a first particle distribution quantity depending on the first set of detection signals and a second particle distribution quantity depending on the second set of detection signals. The apparatus (100) further comprises a determination unit (160) for determining the electromagnetic quantity depending on the first and second particle distribution quantity. The present invention further relates to a corresponding method as well as to a computer program.

摘要翻译： 本发明涉及一种用于确定表征物体特别是人体的电磁特性的至少一个电磁量的装置（100），其中所述物体包含磁性颗粒。 应用已知的磁性粒子成像原理（MPI）的装置（100）包括选择装置，用于产生具有示出场自由点（FFP）的已知场模式的磁选择场（50），用于改变空间位置的驱动装置 通过磁驱动场的FFP的接收装置，用于根据视场内的磁性粒子的磁化获取检测信号的接收装置（28）和用于根据检测重建粒子分布量的重建单元（152） 信号。 该设备（100）还包括控制单元（150），用于控制接收装置，用于获取对应于第一驱动场频率的第一组检测信号和对应于第二驱动场频率的第二组检测信号，两者 驱动场频率彼此不同。 控制单元（15）进一步控制重建单元（152），用于根据第一组检测信号重建第一粒子分布量，并根据第二组检测信号控制第二粒子分布量。 所述设备（100）还包括用于根据第一和第二粒子分布量来确定电磁量的确定单元（160）。 本发明还涉及相应的方法以及计算机程序。

公开(公告)号：US20110163749A1

公开(公告)日：2011-07-07

申请号：US13063477

申请日：2009-09-15

申请人： Ulrich Katscher ,  Ingmar Graesslin

发明人： Ulrich Katscher ,  Ingmar Graesslin

IPC分类号： G01R33/44

CPC分类号： G01R33/3415 ,  G01R33/288 ,  G01R33/5612 ,  G01R33/5659

摘要： A magnetic resonance system comprises: a magnetic resonance scanner (12) including a multi-channel RF transmit system (32, 34); an RF shimming processor (50) configured to compute complex amplitude values for operative channels of the multi-channel RF transmit system based on a figure-of-merit (70) comprising a weighted combination of a B1 uniformity measure and a total power measure; and an RF transmit sub-system (30) configured to drive the multi-channel RF transmit system to excite magnetic resonance using the complex amplitude values computed by the RF shimming processor for the operative channels of the multi-channel RF transmit system.

摘要翻译： 磁共振系统包括：包括多通道RF发射系统（32,34）的磁共振扫描仪（12）; RF匀场处理器（50），被配置为基于包括B1均匀度测量和总功率测量的加权组合的品质因数（70）来计算所述多通道RF发射系统的操作信道的复振幅值; 以及RF发射子系统（30），其被配置为使用由所述RF匀场处理器为所述多声道RF发射系统的操作信道计算的复振幅值来驱动所述多声道RF发射系统来激励磁共振。

公开(公告)号：US20100136929A1

公开(公告)日：2010-06-03

申请号：US12598448

申请日：2008-04-25

申请人： Peter Vernickel ,  Ulrich Katscher

发明人： Peter Vernickel ,  Ulrich Katscher

IPC分类号： H04B1/02

CPC分类号： G01R33/5612 ,  G01R33/246 ,  G01R33/34076 ,  G01R33/3415 ,  G01R33/3678

摘要： A multi-channel RF transmitter arrangement in the form of, or comprising, a plurality RF antennas, antenna elements, coils or coil elements (11 to 16), for generating an RF field, especially for use in a magnetic resonance imaging (MRI) system for exciting nuclear magnetic resonances (NMR), and a method for generating such an RF field is disclosed. Furthermore, a multi-channel RF transmit system comprising a plurality of RF waveform generators (31, 32, . . . 3n) and RF amplifiers (21, 22, . . . 2n) for generating RF transmit signals for feeding such a multi-channel RF transmitter arrangement, especially for use as an RF excitation system in an MRI system is disclosed.

摘要翻译： 天线元件，线圈或线圈元件（11至16）形式的或包括多个RF天线的多通道RF发射器装置，用于产生RF场，特别是用于磁共振成像（MRI） 公开了用于激发核磁共振（NMR）的系统，以及用于产生这种RF场的方法。 此外，包括多个RF波形发生器（31,32 ...，3n）和RF放大器（21,22 ...，2n）的多通道RF发射系统，用于产生RF发射信号， 公开了一种特别用作MRI系统中的RF激励系统的射频发射机布置。

公开(公告)号：US07701211B2

公开(公告)日：2010-04-20

申请号：US11721544

申请日：2005-12-19

申请人： Ulrich Katscher ,  Christian Findeklee ,  Peter Vernickel ,  Christoph Leussler

发明人： Ulrich Katscher ,  Christian Findeklee ,  Peter Vernickel ,  Christoph Leussler

IPC分类号： G01V3/00

CPC分类号： G01R33/3607 ,  G01R33/5611

摘要： The present invention relates to a magnetic resonance imaging system (1) comprising a plurality of RF coils (4) forming a multi-coil array and furthermore to a magnetic resonance imaging method for such a system. In order to provide an MR imaging system and method in which a desired excitation pattern is achieved in a simple way, it is suggested to utilize an analytical procedure how to combine the single coil elements to obtain the most homogeneous B1 excitation possible with a given coil array. In other words, the homogeneity of the B1 field is improved in a very simple way. The sensitivity of each RF coil (4) of the coil array is scaled or weighted by a complex factor, i.e. phase and amplitude of each coil drive signal is adjusted accordingly. These complex factors are determined analytically utilizing the sensitivities S(8) of the coil elements (4) and the desired excitation pattern P (IO, 11). The invention allows an optimized control of the field distribution (RF shimming) for arbitrary RF coil arrays. With the invention a fast and easy independent phase and amplitude control of the coil elements (4) is provided for reducing body-induced RF non-uniformities, which appear in high field MR systems.

摘要翻译： 本发明涉及包括形成多线圈阵列的多个RF线圈（4）以及此类系统的磁共振成像方法的磁共振成像系统（1）。 为了提供以简单的方式实现期望的激励模式的MR成像系统和方法，建议使用分析程序如何组合单个线圈元件以获得可用于给定线圈的最均匀的B1激励 数组。 换句话说，B1场的均匀性以非常简单的方式得到改善。 线圈阵列的每个RF线圈（4）的灵敏度被复合因子缩放或加权，即相应地调整每个线圈驱动信号的相位和幅度。 利用线圈元件（4）的灵敏度S（8）和期望的激励模式P（IO，11）来分析地确定这些复杂因素。 本发明允许对任意RF线圈阵列的场分布（RF匀场）的优化控制。 利用本发明，提供线圈元件（4）的快速且容易的独立相位和幅度控制，用于减少出现在高场MR系统中的体引起的RF不均匀性。