公开(公告)号：US20070240234A1

公开(公告)日：2007-10-11

申请号：US11707631

申请日：2007-02-16

申请人： Stephen Watson

发明人： Stephen Watson

IPC分类号： G06F7/04

CPC分类号： H04N7/163 ,  H04N5/913 ,  H04N7/1675 ,  H04N21/23476 ,  H04N21/4181 ,  H04N21/4182 ,  H04N21/4367 ,  H04N21/4405 ,  H04N21/4627 ,  H04N21/8355 ,  H04N2005/91364

摘要： The invention provides a method of recovering from de-synchronization attacks includes registering original and altered digital content using nonlinear transformations to iteratively attempt to provide better-approximated registration. Approximation occurs at more than one level of granularity, by selecting among a greater number of possible transformation functions at each step. Transformations and comparisons might be conducted directly on pixel values, on coefficients for a set of basis wavelets, or on some transformation of the original and altered digital content. A human operator might assist this process, such as by suggesting transformations or providing evaluation of the degree of registration. Upon resynchronization, embedded identifying information in the original digital content is recovered.

公开(公告)号：US20070060596A1

公开(公告)日：2007-03-15

申请号：US10576460

申请日：2004-10-21

申请人： Gerard Giblin ,  Adrian Hall ,  David Hurst ,  Xiao Lewell ,  Olivier Lorthioir ,  Stephen Mickeown ,  Tiziana Scoccitti ,  Stephen Watson

发明人： Gerard Giblin ,  Adrian Hall ,  David Hurst ,  Xiao Lewell ,  Olivier Lorthioir ,  Stephen Mickeown ,  Tiziana Scoccitti ,  Stephen Watson

IPC分类号： A61K31/519

CPC分类号： C04B35/632 ,  C07D207/34 ,  C07D231/14 ,  C07D401/12 ,  C07D409/04

摘要： Compounds of formula (I) or a pharmaceutically acceptable derivative thereof: wherein W, X, Y, Z, R1, R2a, R2b, and Rx, R8 and R9 are as defined in the specification, a process for the preparation of such compounds, pharmaceutical compositions comprising such compounds and the use of such compounds in medicine.

摘要翻译： 式（I）化合物或其药学上可接受的衍生物：其中W，X，Y，Z，R 1，R 2a，R 2b， >，且R x，R 8和R 9如说明书中所定义，制备这些化合物的方法，药物组合物 包括这些化合物和这些化合物在医药中的用途。

公开(公告)号：US20060235074A1

公开(公告)日：2006-10-19

申请号：US10569812

申请日：2004-08-12

申请人： Ian Holmes ,  Stephen Watson

发明人： Ian Holmes ,  Stephen Watson

IPC分类号： A61K31/277 ,  A61K31/195 ,  C07C255/50 ,  C07C237/36

CPC分类号： C07C235/78 ,  C07C233/51 ,  C07C235/34 ,  C07C255/57 ,  C07C2601/14 ,  C07D209/08 ,  C07D333/24

摘要： Compounds of Formula (I): wherein: R1 is optionally substituted —C4-12 alkyl, —C2-10alkylcycloalkyl, —C2-6alkylheterocycloalkyl, —C2-6alkylaryl, optionally substituted 5- or 6-membered aryl or heteroaryl with the proviso that R2 in not pyridinyl; Z is a bond, CH2, O, S, SO, SO2, NR4, OCR4R5 or CR4R5O; or Z, R1 and Q together form an optionally substituted fused tricyclic group; Q is an optionally substituted 5- or 6-membered aryl or heteroaryl ring; X is COR3; R2 is CONH2, CO2H, CO2R7, SO2R7 or SO2NR8R9, with the proviso that R2 is not CO2R7, when X is CONH2; R3is OR6 or NR8R9; R4 and R5 each independently is H, C1-6 alkyl or C1-4 alkylaryl; R6is H or C1-6 alkyl; R7 is C1-6 alkyl; and R8 and R9 each independently is H or C1-6 alkyl; or R8 and R9 together with the nitrogen atom to which they are attached form a 5- or 6-membered ring which may optionally include 1 or more further heteroatoms selected from O, S and N; or physiologically functional derivatives thereof, with the proviso that formula (I) compounds are not: [3-(acetylamino)-4-cyclohexylphenyl]-butanedioic acid and 3-(acetylamino)-4-cyclohexylphenyl]-butanedioic acid diethyl ether; butanedioic acid [3-methoxy-4-(phenylmethoxy)phenyl]; or butanedioic acid [4-(phenylmethoxy)phenyl]; and with the proviso that when R1 is C4-12alkyl, Z is other than a bond, O or CH2; and physiologically functional derivatives thereof, processes for their preparation, pharmaceutical formulations containing them and their use as inhibitors of matrix metallproteinase enzymes (MMPs) are described.

公开(公告)号：US5891617A

公开(公告)日：1999-04-06

申请号：US380099

申请日：1995-01-30

申请人： Stephen Watson ,  Mehmet Toner

发明人： Stephen Watson ,  Mehmet Toner

IPC分类号： F25D17/02 ,  A01N1/02 ,  B65D55/06 ,  B65D77/04 ,  B65D77/20 ,  B65D85/50

CPC分类号： A01N1/02 ,  A01N1/0221 ,  A01N1/0263 ,  A01N1/0284 ,  B65D55/06 ,  B65D77/0486 ,  B65D85/50

摘要： This invention is directed to cryopreservation of harvested mammalian tissues and living cultured tissue equivalents made by in vitro technology. The invention involves immersing a mammalian tissue or cultured tissue equivalent in a cryoprotectant solution, agitating the cryoprotectant solution and the immersed tissue to achieve effective penetration of the cryoprotectant solution into the tissue, and then freezing the tissue at a very slow freezing rate at 0.3.degree. C. or less/min. In the freezing step, extracellular ice formation is initiated by seeding. The cryopreserved tissue may be stored for indefinite periods of time prior to use. The cultured tissue equivalent is an in vitro model of the equivalent human tissue, such as skin or cornea, which, when retrieved from storage can be used for transplantation or implantation in vivo or for screening compounds in vitro.

摘要翻译： 本发明涉及通过体外技术制备的收获的哺乳动物组织和活的培养组织等同物的低温保存。 本发明涉及将哺乳动物组织或培养组织当量浸入冷冻保护剂溶液中，搅拌冷冻保护剂溶液和浸入的组织以实现冷冻保护剂溶液有效穿透到组织中，然后以非常低的冷冻速率在0.3℃下冷冻组织 C.或更少/分钟。 在冷冻步骤中，通过播种开始细胞外冰的形成。 冷冻保存的组织可以在使用前储存无限期。 培养的组织等价物是等效人体组织的体外模型，例如皮肤或角膜，当从储存中取出时可以用于体内移植或植入或用于体外筛选化合物。

公开(公告)号：US08154886B2

公开(公告)日：2012-04-10

申请号：US12056989

申请日：2008-03-27

申请人： Mark Hendrix ,  Stephen Watson ,  Chuck Mann

发明人： Mark Hendrix ,  Stephen Watson ,  Chuck Mann

IPC分类号： H02B1/20

CPC分类号： H05K7/20563

摘要： A cable organization unit includes a housing. A tray is attached to the housing by at least one slide, and is movable between a first position and a second position relative to the housing. A hood is removably secured to the tray. A user may remove the hood from the tray to access adapters attached to a bulkhead on the tray. The tray may include a latch for securing the tray to the housing in the first position, and the hood may be removed from the tray while the tray is in the first or second positions. A retainer is optionally attached to the housing. The retainer includes an adjustable opening which may be reduced in size such that edges of the opening frictionally engage and hold a jacket of a cable passing therethrough.

摘要翻译： 电缆组织单元包括外壳。 托盘通过至少一个滑块附接到壳体，并且可相对于壳体在第一位置和第二位置之间移动。 罩可拆卸地固定在托盘上。 用户可以从托盘上取下机罩，以便访问连接到托盘上的隔板的适配器。 托盘可以包括用于在第一位置将托盘固定到壳体的闩锁，并且当托盘处于第一或第二位置时，罩可以从托盘移除。 保持器可选地附接到壳体。 保持器包括可调节的开口，其可以减小尺寸，使得开口的边缘摩擦地接合并保持穿过其中的电缆的护套。

公开(公告)号：US20080239693A1

公开(公告)日：2008-10-02

申请号：US12056989

申请日：2008-03-27

申请人： Mark Hendrix ,  Stephen Watson ,  Chuck Mann

发明人： Mark Hendrix ,  Stephen Watson ,  Chuck Mann

IPC分类号： H02B1/20

CPC分类号： H05K7/20563

摘要： A cable organization unit includes a housing. A tray is attached to the housing by at least one slide, and is movable between a first position and a second position relative to the housing. A hood is removably secured to the tray. A user may remove the hood from the tray to access adapters attached to a bulkhead on the tray. The tray may include a latch for securing the tray to the housing in the first position, and the hood may be removed from the tray while the tray is in the first or second positions. A retainer is optionally attached to the housing. The retainer includes an adjustable opening which may be reduced in size such that edges of the opening frictionally engage and hold a jacket of a cable passing therethrough.

摘要翻译： 电缆组织单元包括外壳。 托盘通过至少一个滑块附接到壳体，并且可相对于壳体在第一位置和第二位置之间移动。 罩可拆卸地固定在托盘上。 用户可以从托盘上取下机罩，以便访问连接到托盘上的隔板的适配器。 托盘可以包括用于在第一位置将托盘固定到壳体的闩锁，并且当托盘处于第一或第二位置时，罩可以从托盘移除。 保持器可选地附接到壳体。 保持器包括可调节的开口，其可以减小尺寸，使得开口的边缘摩擦地接合并保持穿过其中的电缆的护套。

公开(公告)号：US20080195661A1

公开(公告)日：2008-08-14

申请号：US11704174

申请日：2007-02-08

申请人： Stephen Watson ,  Elliott Pearl

发明人： Stephen Watson ,  Elliott Pearl

IPC分类号： G06F17/30

CPC分类号： G06F16/634 ,  G06F16/68

摘要： Digital media recognition without substantial user interaction, using information from personal digital libraries, or about users. Digital media recognition ambiguities resolved using that information, including: a preponderance of entries in the user's personal library, including specific songs, authors, or genres; a similarity relationship between the user's personal library and the corpus of a collective library; demographic or specific information about the user; equality to a song already present; earlier results in resolving ambiguities; location of a mobile system in a designated region; location in a designated place within a house; existence of any parental controls; whether the imported digital entertainment information is being imported in bulk as part of a collection; whether, according to a selected similarity metric for digital entertainment information, the imported digital entertainment information would be “closer” to one or more elements of the user's personal library.

摘要翻译： 数字媒体识别，无需实质的用户交互，使用个人数字图书馆或用户的信息。 使用该信息解决数字媒体识别模糊度，包括：用户个人图书馆中的条目优势，包括特定歌曲，作者或流派; 用户个人图书馆与集体图书馆语料库之间的相似关系; 有关用户的人口统计信息或特定信息; 已经存在的歌曲平等 较早的结果解决了歧义; 移动系统在指定地区的位置; 位于房屋内指定的地点; 存在任何家长控制; 导入的数字娱乐信息是否作为收集的一部分批量进口; 根据数字娱乐信息的选择的相似性度量，导入的数字娱乐信息将“更接近”到用户的个人图书馆的一个或多个元素。

公开(公告)号：US20070242862A1

公开(公告)日：2007-10-18

申请号：US11707634

申请日：2007-02-16

申请人： Stephen Watson ,  Daniel Collens ,  Kevin Hui ,  Michael Malcolm

发明人： Stephen Watson ,  Daniel Collens ,  Kevin Hui ,  Michael Malcolm

IPC分类号： G06K9/00

CPC分类号： H04N1/32187 ,  G06T1/0035 ,  H04N1/32165 ,  H04N1/32277 ,  H04N19/467 ,  H04N21/2383 ,  H04N21/23892 ,  H04N21/4348 ,  H04N21/8358 ,  H04N2201/324

摘要： A method of embedding information in digital content representing media streams. The method includes (1) selecting a set of locations within that digital content representing the media stream to embed information, (2) selecting a set of possible alterations to make at those locations, and (3) making a subset of the possible alterations. The set of locations and possible alterations is herein sometimes called a “watermark.” The subset of actual alterations that are made is herein sometimes called a “fingerprint.” The method determines a set of locations at which there are alternative versions of digital content representing the same media stream, such as one being the original and one being an alternative version of the same digital content, herein sometimes called the “original movie” and the “alt-movie,” or herein sometimes called the “original block” and the “alt-block” for a particular block in the digital content representing the media stream.

摘要翻译： 一种在表示媒体流的数字内容中嵌入信息的方法。 该方法包括（1）选择表示媒体流的数字内容中的一组位置以嵌入信息，（2）选择在这些位置处进行的一组可能的改变，以及（3）制作可能的改变的子集。 这里的位置和可能的改变在这里有时被称为“水印”。 所做的实际改变的子集有时称为“指纹”。 该方法确定一组位置，其中存在代表相同媒体流的数字内容的替代版本，例如一个是原始的，一个是相同数字内容的替代版本，在此有时称为“原始电影”，并且 “alt-movie”，或有时称为“原始块”的“alt-block”和表示媒体流的数字内容中的特定块的“alt-block”。

公开(公告)号：US20070174623A1

公开(公告)日：2007-07-26

申请号：US11406066

申请日：2006-04-18

申请人： Stephen Watson

发明人： Stephen Watson

IPC分类号： G06Q99/00 ,  H04L9/00 ,  G06F12/14 ,  H04L9/32 ,  G06F11/30 ,  H04K1/00

CPC分类号： G06Q90/00 ,  G06F21/10 ,  G06F2221/0737

摘要： Embedding fingerprinting or watermarking information includes delivering information in-band within digital content representing a media stream, so unauthorized distributors must choose between degrading the media stream, or leaving sufficient information detectable that unauthorized distribution can be detected. For fingerprinting, the method provides a relatively high degree of confidence of both detecting at least one colluding unauthorized distributor, and not falsely accusing any innocent party of being an unauthorized distributor. Embedding fingerprinting or watermarking information includes selecting a sequence of locations within digital content, and embedding information in the form of a sequence of one or more bits at each of those locations, thus representing a set of marking symbols. Marking symbols cannot be readily manufactured without at least one colluding unauthorized distributor having received it, so any distributed digital content includes at least some marking symbols traceable to at least one colluding unauthorized distributor.

摘要翻译： 嵌入指纹或水印信息包括在表示媒体流的数字内容内带内传送信息，因此，未经授权的分发者必须在降级媒体流之间进行选择，或者留下足够的信息，可以检测到未经授权的分发。 对于指纹识别，该方法提供了相对较高的置信度，既检测到至少一个共谋的未经授权的分发者，也不会虚假地指责任何无辜方是未经授权的分发者。 嵌入指纹或水印信息包括选择数字内容中的位置序列，并且以这些位置中的每一个的一个或多个位的序列的形式嵌入信息，从而表示一组标记符号。 标记符号不能容易地被制造而没有至少一个共同未经授权的分配器已经收到它，所以任何分布式数字内容包括至少一些可追溯到至少一个未经授权的分配器的勾结的标记符号。

公开(公告)号：US07036024B2

公开(公告)日：2006-04-25

申请号：US10378046

申请日：2003-02-28

申请人： Stephen Watson

发明人： Stephen Watson

IPC分类号： G06F1/24

CPC分类号： H04N5/913 ,  H04N7/163 ,  H04N7/1675 ,  H04N21/23476 ,  H04N21/4181 ,  H04N21/4182 ,  H04N21/4367 ,  H04N21/4405 ,  H04N21/4627 ,  H04N21/8355 ,  H04N2005/91364

摘要： Embedding fingerprinting or watermarking information includes delivering information in-band within digital content representing a media stream, so unauthorized distributors must choose between degrading the media stream, or leaving sufficient information detectable that unauthorized distribution can be detected. For fingerprinting, the method provides a relatively high degree of confidence of both detecting at least one colluding unauthorized distributor, and not falsely accusing any innocent party of being an unauthorized distributor. Embedding fingerprinting or watermarking information includes selecting a sequence of locations within digital content, and embedding information in the form of a sequence of one or more bits at each of those locations, thus representing a set of marking symbols. Marking symbols cannot be readily manufactured without at least one colluding unauthorized distributor having received it, so any distributed digital content includes at least some marking symbols traceable to at least one colluding unauthorized distributor.

摘要翻译： 嵌入指纹或水印信息包括在表示媒体流的数字内容内带内传送信息，因此，未经授权的分发者必须在降级媒体流之间进行选择，或者留下足够的信息，可以检测到未经授权的分发。 对于指纹识别，该方法提供了相对较高的置信度，既检测到至少一个共谋的未经授权的分发者，也不会虚假地指责任何无辜方是未经授权的分发者。 嵌入指纹或水印信息包括选择数字内容中的位置序列，并且以这些位置中的每一个的一个或多个位的序列的形式嵌入信息，从而表示一组标记符号。 标记符号不能容易地被制造而没有至少一个共同未经授权的分配器已经收到它，所以任何分布式数字内容包括至少一些可追溯到至少一个未经授权的分配器的勾结的标记符号。